#MYC_Cancer #systemsbiology at @Uni_WUE with @NevenkaDudvars1 @MV4_11 @_BikashAdhikari @J_Hofstetter1 @ashwin_narain @PranjScripts @EingLorenz
Kiel, Germany
Joined March 2019
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We are recruiting: ERC- and DFG-funded PhD positions in Tumor Biology (Kiel, Germany). We look forward to your application!
Congratulations @_MarkusVogt for delivering a superb PhD defense!!!🍾🥂
Graduate students and postdocs interested in PROTACs and Glues: Register for the AEK workshop November 4-6 in Berlin with outstanding international speakers: aek-conferences.org/autumnsc…
Many thanks to the press office of Kiel University for the press release about our new paper in GUT: uni-kiel.de/de/detailansicht…
We are recruiting: ERC- and DFG-funded PhD positions in Tumor Biology (Kiel, Germany).
We look forward to your application!
Congratulations to @ashwin_narain for delivering an outstanding doctoral defense!!! 🎉
A Celebration-delayed major update: @_BikashAdhikari successfully defended his PhD 🎓Congratulations Bikash! 🥳🥳
Congratulations to @Pol2Runner on an excellent defense of his exceptional doctoral work! Well-deserved success and many more to come!!!
Now, for 🤯 part : SPT6 is essential for recruiting termination factors and preventing replication stress !! We saw that acute SPT6 depletion causes readthrough at protein-coding genes 3/4
Happy to share the latest study from our lab, led by @Pranjscripts @ashwin_narain @Pol2Runner in collaboration with @erhard_lab, now out in @MolecularCell !! Using #TPD #genomics #proteomics and #MathematicalModeling, we found dual roles of SPT6 in #transcription 🧵
Congrats to @J_Hofstetter1 for delivering an outstanding defense for her doctoral work !! May the successful streak continue in future !!!!
Happy to announce that we have developed a new compound, a "cancer shredder", which destroys AURORA-A, a protein which causes #cancer development, all thanks to @grk2243 @Uni_WUE. Details here: rb.gy/czsusb. Link 2 paper from @_BikashAdhikari: rdcu.be/b7QOc
A new paper from @_WolfLab, @_BikashAdhikari developed a bifunctional AURORA-A degrader that induces the fast and specific degradation of this kinase in cancer cell lines resulting in S-phase arrest and rampant apoptosis go.nature.com/2S4eRuD
Congrats @cogiac @IRoeschert @RVidaletal @WortmannLars @Pol2Runner @SuseWalz !!!! Another fantastic story from @MYCGyvers :) Keep up the solid work. Looking forward to the next one....
It’s out! cell.com/molecular-cell/full… Ever wondered how transcription couples with splicing? We show that the PP1-PNUTS phosphatase promotes that. /1
Physico-Medica Colloquium / Movie night @Uni_WUE - one of the few times the lecture hall got completely full !! #CRISPR #medical #gradschool
Last external speaker of the day - Florian Erhard introduces us how to check gene regulation in single cells !
After intense discussions on MYC antibodies, we move into core transcription mechanisms - Pranjali Bhandare now showcases her efforts to find novel TFs using nascent RNA imaging
Revitalized after lunch - now we go to getting to know about microarrays - not for RNA expression analysis, but for protein-#protein interactions - by @HMaricLab from @RVZ_Wuerzburg
