@aefraley

Assistant professor of medicinal chemistry @ETH Zürich | Deciphering the molecular complexities of nature | Scuba diving, basketball, and yoga enthusiast

Joined May 2019
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  • Followers831
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Looking forward to fostering scientific creativity and innovation in #naturalproducts #biosynthesis, #biocatalysis, and #medchem at @ETH_DCHAB! Thanks to the committee for the opportunity to shape the next generation of scientists in this amazing community at @ETH_en!
ETH Zurich@ETH_en7 Dec 2023
On the proposal of ETH Zurich President @Joel_Mesot , the ETH Board appointed 12 professors and awarded the title "Professor of Practice" once. 👨‍🏫👩‍🏫 brnw.ch/21wF6YH @MortezaAramesh @ellliottt

Twelve professors appointed

At its meeting of 6 and 7 December 2023 and upon application of Joël Mesot, President of ETH Zurich, the ETH Board appointed twelve professors and awarded the title "Professor of Practice" once.  

ethz.ch
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🚨 Keynote speakers announcement 🚨 Happy to share that the keynote seminars of the #CBNP18 will be delivered by Dr. Anna Vagstad (@ETH_en) and Dr. Nico Sbaraini Oliveira (@uwanews). Looking forward to hearing about their excellent work in the natural product field!
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What is the story behind Anna Vagstad's favorite molecule, jawsamycin? @Microbio_ETH, @piel_lab Find out on her #IntroducingAngewandte page xitter.cf/16467437/status/188785… • onlinelibrary.wiley.com/doi/…
Angewandte Chemie@angew_chem7 Feb 2025
Mechanistic Insights Into Post-Translational α-Keto-β-Amino Acid Formation by a Radical S-Adenosyl Methionine Peptide Splicease (Anna L. Vagstad, Jörn Piel and co-workers) @Microbio_ETH @piel_lab • onlinelibrary.wiley.com/doi/…

Mechanistic Insights Into Post‐Translational α‐Keto‐β‐Amino Acid Formation by a Radical S‐Adenosyl...

Noncanonical protein splicing illuminated: Radical S-adenosyl methionine spliceases post-translationally install α-keto-β-amide residues in a widespread family of peptide natural products. Here, we...

onlinelibrary.wiley.com
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Amy Fraley retweeted
D-CHAB@ETH_DCHAB11 Dec 2024
Save the date for the Farewell Lecture of Prof. Karl-Heinz Altmann! In his talk "20 Jahre D-CHAB: Wie es dazu kam und wie es war" he looks back on his time @ETH_en. We hope to see you there! ⭐️Monday, Dec 16, 2024 ⭐️F 30 (Auditorium Maximum), 5.15 pm chab.ethz.ch/en/news-and-eve…
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Another chance to join our group! We are recruiting a PhD student in digital ligand engineering for nanocatalysis. Reposts and spreading the word to interested people in your network appreciated! jobs.ethz.ch/job/view/JOPG_e…
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PhD position open in our group! Email me if you are interested in #biocatalysis 😊 retweet appreciated! Join our team @DCBPunibern in beautiful Bern and meet Bruno too!
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Our group is recruiting a PhD student for a project on combining traditional expert features with deep learning for reaction prediction. Reposts and spreading the word to interested people in your network appreciated! jobs.ethz.ch/job/view/JOPG_e…
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PhD position opening in my research group @UZH_en! Passionate about Natural Products? Join us! The project involves crafting chemical probes to target natural products. Apply now! #PhD #Chemistry #NaturalProducts jobs.uzh.ch/job-vacancies/ph…
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Amy Fraley retweeted
Waser Group@LcsoLab5 Nov 2024
A unique occasion to participate to the Bürgenstock conf. like @BarhamLab @BismutoLab @ML_Contente @stefano_crespi @DumeleLab @aefraley @christine_m_le Jesus Mosquera, Line Naesborg, @MichelRickhaus @FSchaufelberger @NobuyaTsuji Yang Yang, Rong Zhu last year! + 3 industry jsps
Swiss Chemical Society@SwissChemistry5 Nov 2024
Scientific Leaders of the next Generation! 🔔Only 10 days left to apply as a JSP participant for the SCS Bürgenstock Conference 2025 🗓️May 4-8 Brunnen, Switzerland apply now: bc25.scg.ch/jsp-program #bc25 #jsp #scs #switzerland #symposia
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📢 Our lab is hiring! Interested in harnessing the biosynthetic potential of beneficial, human-associated bacteria? We're looking for a passionate #postdoc to engineer gut bacteria for local, in vivo disease detection and drug delivery. Apply now! 👇bit.ly/3T38qIi
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Our team (fraley.ethz.ch/) in D-CHAB and IPW @ETH_en are embarking on some exciting projects with the opening of our lab this year! Consider attending my inaugural lecture this Sept to hear more about how we integrate #naturalproducts and #biocatalysis into #MedChem
D-CHAB@ETH_DCHAB8 Aug 2024
Amy Fraley @aefraley, our new Assistant Professor of Medicinal Chemistry, & her team roam through the kingdoms of life in search of #biosynthetic strategies to produce #therapeutics. Learn more in this article & join the lecture: Sept 18, 2024! @ETH_en chab.ethz.ch/en/news-and-eve…
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📢We are hiring! I am looking for a PhD student to join our young research team which is currently based at @ETH_DCHAB! #PhDposition in Protein Chemistry and Biocatalysis, funded by @snsf_ch Interested? Apply here: benitezmateos.com/phd-protei… RT appreciated!
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JSP program at the Bürgenstock conference 2024 promotes Scientific Leaders of the next Generation from both academia and industry! Class 2024 JSP together with the Bürgenstock president Erick M. Carreira and guest of honor Scott Denmark. #SCS_BC24 #JSPFellow2024 #scs
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Amy Fraley retweeted
Piel Lab@piel_lab22 Mar 2024
An amazing team effort brings us one step closer cracking the nut of #polyketidesynthase reprogramming. In our new paper published in @ScienceMagazine, we shed light on #Engineering these multimodular assembly lines used for #naturalproduct #biosynthesis. science.org/doi/10.1126/scie…

Evolution-guided engineering of trans-acyltransferase polyketide synthases

Single-molecular tension sensors reveal cellular force loading rate during mechanotransduction.

science.org
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Amy Fraley retweeted
TeufelLab@TeufelLab1 Feb 2024
I have one open Postdoc position (100%, natural product biosynthesis, protein biochemistry) & one PhD position (100%, natural products against glioblastoma brain cancer). Join our lab with great colleagues and salaries located in vibrant Basel. Please RT! jobs.unibas.ch/?lang=en
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Pleased to share a postdoc opportunity with us - come join our awesome group in beautiful Switzerland 🇨🇭 Postdoctoral Research in Molecular and Systems Biology & Toxicology @Toxicology_ETH @ETH_en @ETH_BSSE @ETH_DBIOL @ETH_DCHAB jobs.ethz.ch/job/view/JOPG_e…
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Thank you to those who have supported me along this journey starting from an @NSF REU and PhD at @UMichPharmacy and @UMLifeSciences with @davidhsumich and Janet Smith to a postdoc with @piel_lab at @ETH_DBIOL. Truly inspirational mentors and excellent role models!
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Amy Fraley retweeted
Piel Lab@piel_lab6 Dec 2023
Exciting news! Did Acidobacteria also pop-up in your MAGs? In our new paper we identify sponge-type polyketides from this unusual phylum: sciencedirect.com/science/ar… Have a read for more details. We are excited to see where else we can find Acidos!
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We have Postdoc and PhD opportunities in our group to work on projects ranging from medicinal chemistry to DNA damage and aging to in vitro toxicology-check the lab’s post for more details and please spread the word, thanks! 👩🏽‍🔬👨🏽‍🔬🧪🧬🧫🇨🇭
ETH Zurich Laboratory of Toxicology@Toxicology_ETH3 Nov 2023
We are hiring! Please join us in Zurich! Three positions: postdoc in biological and medicinal Chem with a synthesis focus, postdoc with an in vitro toxicology focus. also an opening for PhD student in DNA damage and ageing.
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Amy Fraley retweeted
Piel Lab@piel_lab6 Sep 2023
We are very proud of @clarachepkirui7 giving such a fantastic talk at #MaNaPro and #ECMNP in #Granada! If you fancy talking more about unusual bacteria and their exciting chemistry, she will be around the rest of the week and is happy to talk about her research!
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