Alison Tarke (@aetarke) header
Alison Tarke (@aetarke) profile picture

T cell immunology Postdoc @ljiresearch

Joined September 2012
Photo by Alison Tarke (@aetarke)Photo by Alison Tarke (@aetarke)Photo by Alison Tarke (@aetarke)Photo by Alison Tarke (@aetarke)Photo by Alison Tarke (@aetarke)Photo by Alison Tarke (@aetarke)Photo by Alison Tarke (@aetarke)Photo by Alison Tarke (@aetarke)
Our new study just published in @CellRepMed shows that SARS-CoV-2 vaccine breakthrough infections (BTIs) have a positive effect on T cell responses! 1/8 cell.com/cell-reports-medici… @SetteLab @Alba_Grifoni @profshanecrotty @P1RAD @TertuAPN @LJIresearch
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We also identified novel epitopes recognizing variant-specific mutations, accounting for 9-15% of the total epitope repertoire. This indicates that the T cell response is responding to variant evolution and is able to generate new responses to the evolving virus. 7/8
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Read more about our study in the full manuscript to learn how BTI influences T cell immunity against SARS-CoV-2 variants. cell.com/cell-reports-medici… Stay tuned for updates on our research! 8/8
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Alison Tarke is the North American winner of the “Science, She Says! Award” (ed. 2024) ENG life.unige.it/en/alison-tark… ITA life.unige.it/alison-tarke #UniGe #UniGenova #Immunology Photo credit: Matthew Ellenbogen @ljiresearch @SetteLab @aetarke @mellenbog3n
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I’m honored to receive this award from @ItalyMFA_int recognizing my contributions as a woman in science. It was a great opportunity to meet fellow award winners representing Asia and Africa and discuss our work together. Grazie mille! #scienceshesays
Congratulations to LJI Postdoc Alison Tarke, Ph.D., North American winner of the @ItalyMFA_int “Science, She Says! Award!” Tarke established important U.S.-Italy research collaborations amidst the COVID-19 pandemic bit.ly/44zNlde @aetarke @SetteLab @UniGenova #COVID19
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New findings from @SetteLab, @Alba_Grifoni, and @aetarke! 🔎T cells against alpha or beta common cold #coronaviruses tend to be cross-reactive 🔎These viruses have MANY similarities in epitope sequences 🔎T cells showed cross-reactivity in 89% of tests bit.ly/42nm0bs
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Thank you to Dr. Fauci for sharing important LJI #SARSCoV2 findings at the recent @ImmunologyAAI meeting! This critical research was led by @SetteLab @profshanecrotty @Dani6020 @Alba_Grifoni @aetarke Ricardo Da Silva Antunes and John Sidney 🔬 Watch: youtu.be/Sr7KiOrg2sA
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Recently graduated and interested in viral immunology? We have a full-time open position as a research tech @ljiresearch appy now! Ihttps://www.linkedin.com/jobs/view/3427081522
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Our team is hiring! We're looking for a research technician with interest in COVID-19 and other viral diseases. It's a great opportunity for a recent graduate or early career scientist! And lots of fun working with @SetteLab & @Alba_Grifoni 😄 👀 us63.dayforcehcm.com/Candida…
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Can CD4+ T cells cross-recognize different coronaviruses (CoV), offering immune protection from potential future CoV pandemics? We explore this concept in our new study, just posted in pre-print. biorxiv.org/content/10.1101/… @Alba_Grifoni @SetteLab 1/5
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We found that T cells can recognize different viruses when the coronavirus sequences were conserved. Specifically, if conservation was >67%, we observed cross-reactivity in 89% of the fragments tested. 4/5
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We found limited cross-reactivity in the sarbeco CoV group (containing SARS2) in our samples collected before the SARS2 pandemic, suggesting that exposure may contribute to the ability of T cells to recognize phylogenetically similar viruses. 5/5
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