Mechanisms of cancer growth and survival. Odd tyrosine kinases, autophagy, and the dynamic signaling hub of 14-3-3. @huntsmancancer @UUtah
Salt Lake City, UT
Joined March 2015
- Tweets353
- Following278
- Followers310
- Likes2.3K
Josh Andersen retweeted
🚨Out in @MolecularCell, “Molecular Determinants and Signaling Effects of PKA RIα Phase Separation” by @a_hardy_girl establishes that a non-canonical, active PKA R:C complex in RIα condensates sequesters PKA activity from the cytosol. tinyurl.com/MolDetRIa
Josh Andersen retweeted
Flashing the U with @JudithSimcox at #DiscoverBMB and flashing back to our shared time at @UofUBiochem
Josh Andersen retweeted
Our paper on functional discovery of protein degradation and stabilization effectors with proteome-scale induced proximity screens is out in its final version! 1/ nature.com/articles/s41586-0… rdcu.be/dBUju
Josh Andersen retweeted
Targeted protein degradation/ stabilization are of therapeutic value, but only few E3 ligases and deubiquitinases have been of use for this purpose. Work @Nature adds to this repertoire, providing a catalogue of effectors of protein stability. nature.com/articles/s41586-0…
Josh Andersen retweeted
Check out our new review article on ciliary signaling, now online at @NatRevMCB - a great collaboration with @Hilgendorf_Lab and @ReiterLab!
Our latest review article in NRMCB is out on everyone's favorite signaling organelle, the primary cilium!
It was truly a real pleasure to work on this with @Myers_lab and @ReiterLab.
Josh Andersen retweeted
Nature review article: A break in mitochondrial endosymbiosis as a basis for inflammatory diseases go.nature.com/3OAPC0C
Josh Andersen retweeted
Congratulations Alex! Another bit of the ATG9A puzzle
Exploring the ATG9A interactome uncovers interaction with VPS13A journals.biologists.com/jcs/…
Josh Andersen retweeted
We are immensely grateful to @utahcityutah for their generous land donation and for the exciting vision they have created. This new campus in Utah County promises expanded world-class care, breathtaking views, and reduced travel burden for patients: bit.ly/3vTfPkQ
Josh Andersen retweeted
Thanks to the visionary developers of @UtahCityUtah—Woodbury Corporation & Flagship Companies, along with @VineyardCity, we've received an incredible $20 million land donation. This will pave the way for a state-of-the-art HCI campus in Utah County. bit.ly/3vTfPkQ
Josh Andersen retweeted
Our lab at @huntsmancancer @UUtah is hiring a junior-level tech!
Come work on fascinating questions in signaling, development, and cancer with a dynamic and collaborative team.
Great opportunity for future grad or med school applicants. Please RT!
utah.peopleadmin.com/posting…
Josh Andersen retweeted
New @biorxivpreprint from our lab by @Qian37774492 on a covalent 14-3-3 molecular glue with the transcription factors YAP and TAZ and using this glue as a 14-3-3 recruiter to sequester nuclear neo-substrates into the cytosol! Thanks to #AppleTreePartners & @themarkfdn
biorxiv.org/content/10.1101/…
Josh Andersen retweeted
Endometrial cancer is the most common gynecological cancer and high levels of estrogen promote its development. Researchers at HCI, led by @xedbee and @GertzLab, have identified potential new treatment options for people with endometrial cancer. bit.ly/47GqKwn
Josh Andersen retweeted
Thanks to the @TheHurleyLab for the well written highlight, couldn't be happier to have our paper included alongside the exciting work done by the @TJ_MeliaLab .
Spotlight: Cook and @TheHurleyLab @berkeleyMCB preview two related studies (@tjolivas et al. bit.ly/3LBlFg4 & @DavidGBroadbent et al. bit.ly/41NBx4C), examining the role of ATG9A in autophagosome biogenesis in mammalian cells bit.ly/3MOXmuo
#autophagy
Josh Andersen retweeted
Spotlight: Cook and @TheHurleyLab @berkeleyMCB preview two related studies (@tjolivas et al. bit.ly/3LBlFg4 & @DavidGBroadbent et al. bit.ly/41NBx4C), examining the role of ATG9A in autophagosome biogenesis in mammalian cells bit.ly/3MOXmuo
#autophagy
Josh Andersen retweeted
Greetings, curious minds!
Ever wondered how our captivating cover illustrations come to be? Join us on a thrilling journey as we reveal the secrets of our process, collaborating with labs to create visually stunning masterpieces for the world to behold! 🌟✨ #DrawImpacts
Josh Andersen retweeted
The Royal Society, the world’s oldest science academy, has elected Bradley R. Cairns, PhD, to the Fellows of the Royal Society. He is one of eighty new members announced earlier this month. #HCIproud bit.ly/45geb9S
Josh Andersen retweeted
Did you know he didn't start working on genome editing until he was 52? It's never too late to start something world-changing. A well-deserved standing O for Dana Carrroll @UofUBiochem @UofUHealth @UUtah and his incredible career. Learn more: attheu.utah.edu/facultystaff…
Josh Andersen retweeted
Today, MIT celebrates the inauguration of President Sally Kornbluth. The festivities kicked off Saturday with Community Day, featuring a street fair and concert. Today’s events include a symposium, ceremony, and inaugural celebration concert. mitsha.re/XSIu50O4Xzg
ALT Anat Cohen playing the clarinet.
ALT Djuena Tikuna singing into a microphone.
ALT MIT president Sally Kornbluth and her family applauding in Kresge auditorium.
Josh Andersen retweeted
PIKFYVE inhibition mitigates disease in models of diverse forms of ALS: Cell cell.com/cell/fulltext/S0092…