@appletonlab

🇨🇦 Rheumatologist, scientist, dad, he/him, advocate for #healthcare, #rheumatology, #research, #osteoarthritis. Tweets my own

 London, Canada
schulich.uwo.ca/appletonlab
Joined March 2011
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🚨New American College of Rheumatology Recommendations Put Personalized Os... youtu.be/Hpe7JtaIIhc?si=aoHW… via @YouTube #GLP1 #exercise #osteoarthritis @ACRheum

New American College of Rheumatology Recommendations Put Personalized...

In the new 2026 Osteoarthritis Guideline Summary, the ACR provides ...

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🚨Standard scRNA-seq often excludes cells with high mitochondrial RNA content (pMT).🚨 Work by Tran et al. investigates how exclusion of high-pMT cells affects the transcriptional landscape of knee OA synovium and explores their role in disease. 🔗sciencedirect.com/science/ar…
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📢 “When we first started to see the big effects of these blockbuster #GLP1 drugs, people were talking about weight loss from Hollywood to regular people’s homes,” said Dr. Tom Appleton @appletonlab. Read the Healio Exclusive @HealioRheum 👇 vist.ly/4tb3a

From Hollywood to rheumatology: GLP-1s may represent a ‘new chapter’ in health care

Interest in the use and impacts of glucagon-like peptide-1 receptor agonists in rheumatology has exploded over the past year, a trend that appeared to crescendo at ACR Convergence 2025. There,...

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