Arne retweeted
In light of the launch of Cell Press Blue cell.com/cell-press-blue/hom…, I want to let everyone know about @biorxivpreprint Blue
Arne retweeted
David’s life’s work was a disposable prop for MIT to market its virtue to a woke audience.
Some are even arguing that David deserved to lose his career because he was romantically involved with a woman in the workplace. That is an absurd and hypocritical justification for what MIT did to him.
Reducing the destruction of his career to a workplace relationship policy violation is grotesque hypocrisy. A romantic relationship at work is an ordinary part of academic life for administrators and an excuse for destroying a laboratory when it involves someone they don’t like.
His relationship with Knouse even began before Whitehead updated its relationship policies in August 2018.
If a workplace relationship warrants professional destruction, MIT and all universities, for that matter, have a great deal of firing to do. Erin O’Shea, who was instrumental in firing David from HHMI, dated and married someone who earned his PhD in her own laboratory. Ruth Lehmann, who forced David out of Whitehead, has a long-time partner who was a fellow scientist at NYU, where she worked. MIT’s president, Sally Kornbluth, is married to an MIT biology professor. These administrators know perfectly well that scientists form romantic relationships within their professional communities.
Scientists spend enormous portions of their lives in their laboratories and around other scientists. They develop relationships within that world because they devote themselves to their craft and have little social life outside it. Universities know this, and so do their administrators.
The court also rejected Knouse’s claim that she experienced quid pro quo sexual harassment from David. The court found that David did not condition professional benefits or consequences based on sex. She directed her own lab and she went on to obtain a tenure-track position at MIT. Invoking a poorly defined “power imbalance” does not erase the court’s rejection of her claim.
people.com/mit-scientist-dav…
Arne retweeted
Replying to @healthisavibe @LocasaleLab
Looked up the Whitehead policy; it’s crazy restrictive. Originally it matched MIT’s. Aug 2018 amended, taking unusually aggressive stand against workplace romance. New rule explicitly banned faculty, sr managers & PIs from sexual relationships w/any Whitehead employee—even peers
Arne retweeted
MIT claimed that its actions against David were based on findings about the culture in his lab. The $6M verdict invalidates that explanation.
The jury awarded David $6M for damages caused by Knouse’s defamation. This means not only that false statements were made, but that those statements were proven to have caused a huge amount of damage. A causal connection between Knouse’s statements and the harm David suffered was established in court. The damage he endured came from the actions of MIT, Whitehead, and HHMI and their authority over him.
The implication of the court ruling is that those actions occurred because of the false statements, rather than for other reasons such as a vaguely defined lab culture.
A “toxic work environment” is a vague, slippery, often unfalsifiable slur that can be attached to anyone directing a laboratory or any group of people. Falling back on that label was a way to hide the real reasons for their actions from the public and look good to their base. Nobody likes an abusive boss, especially students who like to protest.
But I knew so many people who had worked under his supervision. They did not see him or his lab that way, even though they were not speaking publicly.
Some are saying that because MIT and Whitehead were not held liable, they are exonerated from this mess. Nothing could be further from the truth.
These institutions have sophisticated, eight-figure legal operations and substantial resources devoted to shielding them from liability. They know how to word damaging public statements while protecting themselves against defamation claims. They also know how to invoke attorney-client privilege, work-product protection, and other privileges to shield their dirty business from public scrutiny. Their ability to defend themselves legally should not be confused with institutional integrity.
Faculty employment is generally at will. That means an employer can fire someone for any or no reason. Tenure is a policy, not a legal right. Faculty are sold the promise of its security, but finding out what protections they can actually enforce when push comes to shove can take years and enormous legal fees. Sally Kornbluth, now MIT’s president, even admitted in court once that tenure does not carry the legal protections faculty believe it does (Shaughnessy v. Duke, see her deposition excerpts in the summary judgment materials). Employment law provides no remedy for many destructive decisions universities make.
Civil rights laws offer protection against discrimination, and pursuing those claims is often the only recourse faculty have in court against a university. But proving discrimination is difficult, especially for a scientist with a unique position and record. David pointed to Knouse as someone treated differently. She also ran a laboratory and had NIH funding, but I think the court ruled they were not similarly situated. He did have a more senior rank and a larger lab. So be it.
But discrimination law only addresses discrimination. You can treat people like garbage and run your institution into the ground without committing actionable discrimination. This is where public accountability must come into play.
The jury found that Knouse defamed David and unlawfully interfered with his livelihood. MIT, Whitehead, and HHMI held the authority, and through their actions, the false allegations against him became career-destroying consequences. That is why this verdict demands accountability from those institutions. They bear responsibility for the damage those actions caused.
You know what I love about this video? It’s not just the music, the lyrics, or the joyful scenes. It also reminds us that, for most Americans, our family stories began somewhere else. That’s part of what has always made America so diverse and vibrant.
Arne retweeted
Pleased to share our paper on a force-activated mechanical transition in the “ankle” of human β-cardiac myosin, with implications for hypertrophic cardiomyopathy. Thanks to Surya, our team, and Leslie Leinwand’s lab. #myosin #AFM #singlemolecule
pubs.acs.org/doi/10.1021/acs…
Arne retweeted
📣 Fully funded PhD position available!
Join our group at MRC-LMB in Cambridge to uncover how human cells coordinate RNA transcription and splicing. You’ll use biochemical, structural & cellular approaches, including #cryoEM.
Apply by 14th April. #PhD
mrclmb.ac.uk/careers-and-peo…
Arne retweeted
I will give an oral presentation about Enterococcus hirae V-ATPase in the International Workshop on Bacterial Flagella and BioMachineries held at Taoyuan, Taiwan on 16-19 March 2026. Thank you very much for giving me an opportunity!
sites.google.com/as.edu.tw/f…
Arne retweeted
Replying to @NIHDirector_Jay
@NIHDirector_Jay Dear Dr. Bhattacharya,
With the FY2026 NIH budget approved, when can labs expect Notices of Award? Many are facing planning and staffing uncertainty. Thank you.
Our work is now published in @NatureCellBio! We show that under mechanical load, dynein–dynactin–adaptor complexes recruit a third dynein via a second cargo adaptor, increasing force generation. This reveals an adaptive mechanism that strengthens intracellular transport under load. @EinsteinMed nature.com/articles/s41556-0…
Arne retweeted
Resolving and tracking identical, continuously emitting fluorophores separated by ~10-20 nm *without* ON/OFF switching or spectral separation! Preprint by Hensel et al.
biorxiv.org/content/10.64898…
@mpi_nat @mpi_mr_hd #Imaging #Optics #Waves #Microscopy #Fluorescence
Arne retweeted
📢 2024 #HighlyCited Paper in Cellular Biophysics Section
𝙎𝙩𝙧𝙪𝙘𝙩𝙪𝙧𝙚 𝙖𝙣𝙙 𝙁𝙪𝙣𝙘𝙩𝙞𝙤𝙣 𝙤𝙛 𝘿𝙮𝙣𝙚𝙞𝙣’𝙨 𝙉𝙤𝙣-𝘾𝙖𝙩𝙖𝙡𝙮𝙩𝙞𝙘 𝙎𝙪𝙗𝙪𝙣𝙞𝙩𝙨
📑 Read the full open-access paper here: brnw.ch/21wYCEc
Arne retweeted
Preprint: arxiv.org/abs/2510.15511
Joint work w/ @GiorgosNik02 @tommaso_mncttn @DonatoCrisosto1 @teelinsan Yannis Panagakis @EmanueleRodola
stay tuned!
(6/6)
Arne retweeted
Spotlight in @JCellBiol from Bhattacharyya and Klumpp: Combining two powerful imaging techniques, Renganathan et al. (hubs.la/Q03ckMSG0) provide unprecedented detail of the intermediate filament network in cells. hubs.la/Q03ck_TW0
#Cytoskeleton #Vimentin
Arne retweeted
I am extremely proud to see our work about Hepatitis B now published in @CellCellPress.
From basic research to identifying the key step of infection & a potential first drug for curing this devastating disease. This has been an incredible journey.🧵
cell.com/cell/fulltext/S0092…
Arne retweeted
1/n
Really excited to share our latest pre-print on the role of cohesin in homology search, now available on bioRxiv!
biorxiv.org/content/10.1101/…
Arne retweeted
My lab at Brown University is hiring a postdoctoral fellow! We develop single-molecule imaging technologies to dissect the spatial regulation of gene expression. For more information about my lab, visit weihan-li.com/ Please help spread the word! #RNA #imaging
Arne retweeted
Geometry-based kinetic simulation of DNA-AuNP motor.
nature.com/articles/s41467-0…
Takanori's paper is out in @NatureComms! We rationally engineered artificial DNA-AuNP motor with high speed and long run-length comparable to motor proteins!
We sincerely appreciate reviewers, and hope you enjoy our paper and 59 pages of peer review file!
nature.com/articles/s41467-0…

























