Biotech VC | @OrbiMed | Classic Rocker | Toronto Ex-Pat | Wannabe New-Yorker | World Traveler | Tweets are my own opinion

New York, NY
Joined September 2011
Jonathan Mandelbaum retweeted
Congratulations to our portfolio company, Forte Biosciences, on its agreement to be acquired by @argenxglobal for $2.2 billion. This milestone follows impressive progress for Forte's lead program, FB102, including positive Phase 1b data in both vitiligo and celiac disease. With Phase 2 celiac data expected later this year and the potential to address additional autoimmune diseases such as alopecia areata, FB102 has demonstrated the promise of becoming a true pipeline-in-a-product. We partnered with Forte in 2024, when FB102 had just completed its healthy volunteer study and was entering clinical evaluation in celiac disease. It has been rewarding to watch the program advance, and we look forward to seeing FB102 continue its development and make a difference for patients. fortebiorx.com/investor-rela…
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Jonathan Mandelbaum retweeted
We're excited to announce positive feedback from our end-of-Phase 2 meeting with the FDA, supporting the development path forward for bitopertin in #EPP and highlighting the potential for accelerated approval. Join us for our webcast at 8am ET: ir.discmedicine.com/news-rel…
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Jonathan Mandelbaum retweeted
This #RareDiseaseDay, join us in raising awareness for the 300 million people globally living with a rare disease, including those with erythropoietic porphyria (#EPP) and other hematologic disorders.
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Jonathan Mandelbaum retweeted
OrbiMed is pleased to announce it has raised more than $4.3 billion in commitments for its latest private investment funds, including OrbiMed Private Investments IX, OrbiMed Asia Partners V and OrbiMed Royalty & Credit Opportunities IV. Read more here: orbimed.com/Data/Content/624…
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Jonathan Mandelbaum retweeted
OrbiMed portfolio company Aliada Therapeutics, along with Chiesi Global Rare Diseases, announces a co-development agreement to advance Aliada's blood-brain barrier-crossing platform technology in lysosomal storage disorders. Read more: prnewswire.com/news-releases…
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Jonathan Mandelbaum retweeted
24 years ago today we played Woodstock ‘99. Here’s how we opened our set, with “Grace, Too”...
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Jonathan Mandelbaum retweeted
In data presented at #EHA2023, Disc announced initial positive results from BEACON, our Phase 2 clinical trial for bitopertin in #EPP. Read more: globenewswire.com/news-relea…
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Jonathan Mandelbaum retweeted
Please join Disc as we host a virtual KOL investor event on Tuesday, April 25, 2023, at 1:00 pm ET / 10:00 am PT to provide an overview of our lead indication #EPP, a rare, severe disease caused by mutations in the heme biosynthesis pathway. globenewswire.com/en/news-re…
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Jonathan Mandelbaum retweeted
Disc is pleased to announce the initiation of our Phase 1b/2 clinical study of DISC-0974 in non-dialysis dependent chronic kidney disease (NDD-CKD) patients with #anemia. Thanks to our fantastic R&D team in getting this study off the ground! globenewswire.com/en/news-re…
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Jonathan Mandelbaum retweeted
Given yesterdays news of $AMGN buying $HZN for $28B I’ve been asked to give color to the Tepezza history by a few people in a Tweet Thread. So here it goes. It’s my fist so be kind.
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Jonathan Mandelbaum retweeted
Disc is delighted to announce the initiation of AURORA, our US-based Phase 2 Study of bitopertin in #EPP patients. Learn more: discmedicine.com/news/disc-m… Bitopertin is an experimental agent and is not approved for use as a therapy in any jurisdiction worldwide.