Chromatin in the brain
Ann Arbor, MI
Joined June 2017
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Awesome lab with many deeply interesting projects!
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Looking forward to the session, it will be fun! Thank you @jasonyilab and @Gabel_Lab for organizing this Interest Group:)
Please spread the word! I will be chairing a special Neuroscience Interest Group at the #ASBMB2021 annual meeting with @Gabel_Lab on April 26. asbmb.org/meetings-events/20…
Shigeki Iwase retweeted
pnas.org/content/118/6/e2016… Recent collaborative effort between our group and the Muir/Li labs investigating novel mechanisms of Histone Serotonylation. Congrats everyone!
Shigeki Iwase retweeted
This is groundbreaking and giving hope for many rare neurodevelopmental disorders. What an idea to split cas9 into two parts and let AAV deliver them throughout the body.
Today we report the use of base editing in patient-derived cells and in mice to correct the most common cause of progeria, the devastating rapid aging disease. Progeria is typically caused by a dominant negative C•G-to-T•A point mutation in LMNA. 1/11 drive.google.com/file/d/1oH4…
Shigeki Iwase retweeted
It's been fun engaging with all the prospective grad students during #umichPIBS recruitment weekend! We have open positions for students interested in:
🧬chromatin🧠neurodevelopment⚕️translational research🐭🧫a variety of model systems 🔬💻wet & dry lab
#PIBS #GradSchool
Shigeki Iwase retweeted
Human genetics and genomics over the last 50 years. What a remarkable half century it's been! We've achieved so much and so many exciting possibilities are within reach.
nejm.org/doi/full/10.1056/NE…
Shigeki Iwase retweeted
We found that loss of Kdm1a in mouse neurons lead to premature activation of neuronal activity-dependent enhancers & genes. A #BasicResearch step towards understanding the associated human #KDM1A / #LSD1 neurodevelopmental syndrome & helping those like @milosjourney.
Shigeki Iwase retweeted
Out this month: our paper showing #KDM1A aka #LSD1 maintains optimal enhancer activity by counterbalancing #H3K4 methylation at enhancers.
Project lead by former postdoc Dr. Saurabh Agarwal & @NGPMichigan PhD candidate @KatieBonefas.
pubmed.ncbi.nlm.nih.gov/3341…
Great opportunity! I am going to apply. – at Pittsfield, MI
We are looking to hire 2 postdocs to investigate the new copper reductase function of histone H3 in biology and disease. Visit kurdistanilab.com to learn more about our science. Send inquiries including a CV to [email protected]. Please RT!
Shigeki Iwase retweeted
A discovery by U-M researchers in the @UMRogelCancer @NarlaLabUMich of a compound that activates an enzyme capable of suppressing tumors was included as one of the @ScienceFocus “Top 20 Moments in Science to Make You Feel Better About 2020.” myumi.ch/yKAlW
ALT Text: U-M research featured as a top moment in science by Science Focus
Shigeki Iwase retweeted
Thinking back on this last year, and it wasn't all bad. We achieved a lot despite the many challenges. Here's a look at our #LabYearInReview:
🎓PhD defenses
🤓new hires
📰published manuscripts
🥳and more!
Shigeki Iwase retweeted
Ready for the new year with a new account 🥳 We are the Iwase Lab group at the University of Michigan and we study chromatin dynamics in the brain 🧬🧠
Shigeki Iwase retweeted
Alan Boyle, #RNA featured scientist: bit.ly/3ge1yDd
@realToddLab @NilsWalterLab @smslmoon @ryan_e_mills @BarmadaLab @UM_Genetics
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Awesome lab to study blood disease mechanisms! – at Pittsfield, MI
Please RT. NIH R01 & R35-funded #postdoctoral positions available to study #blood and #cardiovascular disorders using the #zebrafish model. shavitlab.org. #hemotasis #thrombosis #SciTwitter #MedTwitter #AcademicTwitter #postdocjobs #postdoc #sciencejobs #academicjobs
