Associate professor, Penn State BMB & Chemistry. Computational Biochemist. She/her
Joined February 2016
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Dr. Denise O. retweeted
The nomination period for the 2027 Sloan Research Fellowships is now open!
Established in 1955, the fellowships support fundamental research conducted by early-career scientists.
The deadline for nominations is September 15, 2026.
More info: sloan.org/fellowships
Dr. Denise O. retweeted
One last piece of news to cap off the year.... the Lee lab is now funded by an✨NSF CAREER✨
We'll explore how transgenerational inheritance affects the earliest decisions in C. elegans embryos AND build new CUREs for our first-gen students. 🪱🧬
Funding makes us feel 👇
Dr. Denise O. retweeted
The Booker Lab at the University of Pennsylvania, in Philadelphia, and HHMI is searching for a lab manager. If interested, please apply at the HHMI link below.hhmi.wd1.myworkdayjobs.com/e…
Dr. Denise O. retweeted
Excited to be selected as a Hypothesis Fund awardee! Grateful for the support to pursue bold, early-stage ideas and ask unconventional questions about metabolism, communication, and aging. A reminder to stay curious and authentically yourself in science.
Dr. Denise O. retweeted
Congratulations to ASBMB members @MarmolJosefina (@harvardbrainsci & @hhmi_science) and Denise (@PSUScience), who were recently awarded Sloan Research Fellowships!
Congrats to the 126 early-career scholars awarded a 2026 Sloan Research Fellowship, whose creativity and innovation set them apart as the next generation of scientific leaders! Our Fellows represent 7 fields and 44 institutions across the US and Canada.
sloan.org/fellowships/2026-F…
ALT 2026 Congratulations Sloan Research Fellows!
Dr. Denise O. retweeted
I'm excited to share that @penn_state @cegrPSU is conducting a faculty search this year! It's a fantastic place to work with excellent colleagues, highly talented trainees, interdisciplinary science, and lots of support! Applications are due by October 1st.
Dr. Denise O. retweeted
Remembering David Mangelsdorf, PhD, a 2025 @TheEndoSociety Laureate Award recipient and a much loved leader in the world of endocrine science.
Sharing the Dec. 2024 cover story where he discussed his research with his co-recipient Steven Kliewer, PhD:
endocrinenews.endocrine.org/…
Dr. Denise O. retweeted
In a time as this— I am deeply thankful to be blessed with this honor. As a scientist and educator, the NSF CAREER award allows me to integrate the very core of who I am as a scientist and educator.
Forever grateful to past and present members of the @mcreynolds_lab for helping me accomplish this dream.
Dr. Denise O. retweeted
Super excited to announce today's issue of ACS Bio & Med Chem Au. Please check out our editorial featuring the 2024 Rising Stars in Biological, Medicinal, and Pharmaceutical Chemistry!! #openaccess @ACSBioMed @ALavasanifar pubs.acs.org/doi/10.1021/acs…
Dr. Denise O. retweeted
Now published! Read our newest story! doi.org/10.1038/s41467-025-5…
New-ish @biorxivpreprint from the lab! Ligand efficacy shifts a nuclear receptor conformational ensemble between transcriptionally active and repressive states. Congrats to former postdoc Brian on a great story! Read on for a (slightly) deeper dive 🧵doi.org/10.1101/2024.04.23.5…
Dr. Denise O. retweeted
Congrats to Janine Kwapis, Paul Berg Early Career Professor in the Biological Sciences and assistant professor of biology, for receiving the 2024 McKnight Brain Research Foundation Innovator Award in Cognitive Aging and Memory Loss!
Today is the 5th anniversary of the lab! Thankful for the home I've found at Penn State and the people I've found it with. Happy new year!
I am excited to share our work in @JMolBiol, which is our 7th publication on #nuclearreceptors for the 2024 calendar year! Please read on for a summary of all 7 publications from our lab this year, as well as links to the papers.
6. Simulations Reveal Unique Roles for the FXR Hinge in the FXR–RXR Nuclear Receptor Heterodimer (Nov 2024) in the 2024 Rising Stars in Biological, Medicinal, and Pharmaceutical Chemistry edition of @ACSBioMed ACS Bio & Med Chem Au.
pubs.acs.org/doi/10.1021/acs…
