Kazuhiro Horiba (@cikazda) header
Kazuhiro Horiba (@cikazda) profile picture

Kazuhiro Horiba

@cikazda

Researcher in JPN. ← Postdoc at KI and Nagoya Univ. RIEM. Developer of @pathdet. Pediatrician. InfectiousDisease/Phage/Metagenomics/Bioinformatics.

 Tokyo
orcid.org/0000-0003-3017-299X
Joined August 2021
  • Tweets67
  • Following257
  • Followers74
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Photo by Kazuhiro Horiba (@cikazda)Photo by Kazuhiro Horiba (@cikazda)Photo by Kazuhiro Horiba (@cikazda)Photo by Kazuhiro Horiba (@cikazda)Photo by Kazuhiro Horiba (@cikazda)Photo by Kazuhiro Horiba (@cikazda)
We showed that #nanopore sequencing can be used for both #metagenomic and host #transcriptomic analysis from a single clinical sample with #infectious diseases. @OFIDJournal doi.org/10.1093/ofid/ofac504
Performance of Nanopore and Illumina Metagenomic Sequencing for Pathogen Detection and Transcript...

Performance of Nanopore and Illumina Metagenomic Sequencing for Pathogen Detection and Transcript...

AbstractBackground. Infantile central nervous system infections (CNSIs) can be life-threatening and cause severe sequelae. However, the causative microorga

academic.oup.com
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Our study analyzing both pathogen detection and host gene expression in HLH patients has been published. Cell-free RNA profiling suggested mitochondrial RNAs as potential biomarkers of virus-associated HLH. #mNGS #cfRNA #PATHDET doi.org/10.1002/jmv.71122
Comprehensive Viral Detection and Profiling of Plasma Cell‐Free RNA in Patients With Suspected...

Comprehensive Viral Detection and Profiling of Plasma Cell‐Free RNA in Patients With Suspected...

Hemophagocytic lymphohistiocytosis (HLH) is a severe, rapidly progressive disease. While viral infection is considered a common etiology of pediatric HLH, specific causative viruses other than the...

onlinelibrary.wiley.com
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mNGS found Prevotella spp. in culture-negative pus samples in muscle abscesses.#metagenome #NGS #pathdet sciencedirect.com/science/ar…
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mNGS, using PATHDET pipeline, revealed Fusobacterium arthritis. #ngs #metagenome @pathdet The contribution of metagenomic next-generation sequencing to a diagnosis of gas-producing Fusobacterium-induced septic hip arthritis: A case report sciencedirect.com/science/ar…
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PATHDET detected GAS in a pleural fluid using metagenomic NGS. Severe Parapneumonic Effusion in a Child With Respiratory Syncytial Virus and Streptococcus pyogenes Coinfection cureus.com/articles/327252-s…
Severe Parapneumonic Effusion in a Child With Respiratory Syncytial Virus and Streptococcus...

Severe Parapneumonic Effusion in a Child With Respiratory Syncytial Virus and Streptococcus...

A four-year-old boy with respiratory syncytial virus (RSV) infection and suspected bacterial coinfection deteriorated despite antibiotic treatment. Intensive care and thoracoscopic debridement w...

cureus.com
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Metagenomic Analysis of Lung Microbiome in Patients With Interstitial Lung Diseases and Sarcoidosis: An Experimental Study - Takeuchi - 2025 - Health Science Reports - Wiley Online Library onlinelibrary.wiley.com/doi/…
Metagenomic Analysis of Lung Microbiome in Patients With Interstitial Lung Diseases and Sarcoidos...

Metagenomic Analysis of Lung Microbiome in Patients With Interstitial Lung Diseases and Sarcoidos...

Background and Aims Interactions between the lung microbiome and pulmonary epithelium plays a pivotal role in shaping immunity in the lung. Idiopathic pulmonary fibrosis (IPF) is the most common...

onlinelibrary.wiley.com
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Japanese expert gives seminar on metagenomics | Oswaldo Cruz Institute ioc.fiocruz.br/en/noticias/e…
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A huge thank you to all the team of supporters and collaborators who have stuck with us through part or all of this! @guru_uhuru @cikazda @pathdet Ben Parcell Nick Feasey Nick Leslie Linda Marriott @Amandatron89 @Anamart066 @SepsisUK @ASLM_News @Nsutebu Yoshinori Ito
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Full bloom!!
Image from Kazuhiro Horiba (@cikazda)
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New Selenomonas spp. were found in septic patients. Complete genome sequence of Selenomonas species strain TAMA-11512, isolated from blood culture of a septic patient | Microbiology Resource Announcements journals.asm.org/doi/10.1128… #mra #sepsis #selenomonas #NGS
Complete genome sequence of Selenomonas species strain TAMA-11512, isolated from blood culture of a...

Complete genome sequence of Selenomonas species strain TAMA-11512, isolated from blood culture of a...

Selenomonas species has the properties of anaerobic, Gram-negative, curved, or crescent-shaped rods with flagella originating from the inner curvature of the cell (1). It has been isolated from the...

journals.asm.org
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Kazuhiro Horiba retweeted
Mari Miyamoto (@marimiya_tky) profile picture
Mari Miyamoto@marimiya_tky24 Nov 2023
And his special recipe…
Image from Mari Miyamoto (@marimiya_tky)
Image from Mari Miyamoto (@marimiya_tky)
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Kazuhiro Horiba retweeted
PATHDET (@pathdet) profile picture
PATHDET@pathdet25 Nov 2023
PATHDET's Pathogen Prediction Method receives Japanese Patent, no.7373843.
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We assessed the relationship between gut microbiota and Fontan-associated PLE. doi.org/10.1016/j.ijcard.202…
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日本感染症学会と米国感染症学会(IDSA)のコラボレーションに期待しています😄
IDSA (@IDSAInfo) profile pictureIDSA
@IDSAInfo15 Oct 2023
IDSA leaders and the Japanese Association of Infectious Diseases meet at #IDWeek2023. @yohei_doi
Image from IDSA (@IDSAInfo)
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So @nanopore discovered something a few days ago - and it has to do with light. And they posted this image (sorry, too good not to share off the community). Yes, that’s 469% increased output. So, we decided to give it a shot and …
Image from Mrinalini Watsa (@SurroundScience)
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'A regrettable decision, made without any preceding dialogue with the universities and researchers, - says Annika Östman Wernerson, President of Karolinska Institutet, critisizing the Swedish government’s choice to stop all grants for development research news.ki.se/government-stops-…

Government stops all development research grants

At its meeting of 22 June, the government made the decision to stop all grants disbursed by the Swedish Research Council itemised as development research, effectively pulling the plug on a great deal...

news.ki.se
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Published online! Nanopore sequencing could comprehensively detect RNA viral pathogens in BALF samples with equivalent sensitivity and genome coverage as Illumina sequencing. sciencedirect.com/science/ar… #nanopore #infection #metagenome #respiratory
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#nanopore #illumina #metagenome #clinicalsequence #meningitis #enterovirus nanoporetech.com/resource-ce…
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We found, #Ureaplasma in the newborn's gastric fluid was connected to their mother's chorioamnionitis in cases of #newborn respiratory distress, according to #NGS. #metagenomics doi.org/10.1080/14767058.202…
Next-generation sequencing-based detection of Ureaplasma in the gastric fluid of neonates with...

Next-generation sequencing-based detection of Ureaplasma in the gastric fluid of neonates with...

Respiratory distress is common in neonates admitted to neonatal intensive care units. Additionally, infectious diseases such as intrauterine infections or vertical transmission are important underl...

tandfonline.com
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Our poster presentation about the #bacteriophage genome analysis pipeline for #phagetherapy is at #ECCMID2023. PHINISH pipeline is developed for screening phage genes unsuitable for clinical use. and available for #nanopore, #Illumina, and hybrid seq data.
Image from Kazuhiro Horiba (@cikazda)
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日本臨床微生物学会 一般演題O13−3でナノポアシークエンスによる感染症診断の発表をします。新たな微生物検査法としてのmetagenomic NGSにご興味がある方は是非。#微生物学会34
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