Designer Microbes Inc is a Biotechnology Company with the focus on creating custom microbial strains thru the use of rational design and/or directed evolution.
London, Ontario
Joined October 2014
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DesignerMicrobes Inc retweeted
Huge new work from Japan - radically engineered E.coli genome now half the size of the usual genome. 🧬 🦠
Impressive work… minimising genomes is on the march!
Generating E. coli 0.5 controlled by a half-sized genome biorxiv.org/content/10.64898…
DesignerMicrobes Inc retweeted
Newest paper from our lab lead by @Daniel_Nucifora. We show that the entire genome of A. laidlawii can be transferred directly into yeast by cell fusion. Cloning whole genomes in yeast is a key step toward building and engineering synthetic cells.
pubs.acs.org/doi/10.1021/acs…
DesignerMicrobes Inc retweeted
Excited that our latest diatom engineering research @SchulichMedDent was highlighted by CTV News London! Congrats @ejlwalker and all authors.
ctvnews.ca/london/article/fr…
DesignerMicrobes Inc retweeted
New preprint from Pioneer Labs - BioBloom: a retron-based method for barcoded saturation mutagenesis of the entire E.coli bacterial genome. biorxiv.org/content/10.64898…
DesignerMicrobes Inc retweeted
Seminar on the fascinating coral-algae endosymbiosis, by the experts Professor Virginia Weis and Dr Maria Ruggeri from Oregon State University starts in 10 minutes.
Zoom link: stanford.zoom.us/j/991899049…
DesignerMicrobes Inc retweeted
New Preprint from the Karas Lab: Conjugation-Based CRISPR Antifungals (COBRA). Congrats @VidaNasrollahi
Thank you to our Sponsors @WesternU Western Innovation Fund, @NSERC_CRSNG, Ontario Agri-Food Research Initiative @westernuBiochem
biorxiv.org/content/10.64898…
DesignerMicrobes Inc retweeted
🚨Alert. All domestic students can apply for NSERC Master’s Scholarship
nserc-crsng.gc.ca/Students-E…
We are exploring the frontiers of synthetic biology, building synthetic plants, engineered diatoms, and novel organelles, as well as developing next-generation antifungals
DesignerMicrobes Inc retweeted
Newest preprint from K-lab: Direct Genome Transfer from Acholeplasma laidlawii to Yeast. Congrats to @Daniel_Nucifora Tanveer Saini @SchulichMedDent Thank you for sponsoring this research @NSERC_CRSNG #synbio #GenomeTransfer #SynCell
doi.org/10.1101/2025.10.17.6…
DesignerMicrobes Inc retweeted
Newest preprint from K-lab: Resolving replication incompatibility between chloroplast and conjugative plasmids in E. coli. Congrats @ejlwalker and all authors. @SchulichMedDent Thank you for sponsoring this research @ARIA_research @NSERC_CRSNG biorxiv.org/content/10.1101/…
DesignerMicrobes Inc retweeted
As a wetlab experiments guy, a lot of DL/ML/AI baffles me, so I'm learning a lot supervising @tdsone3 in his PhD to bring AI-based design to synthetic biology in Baker's yeast. His first output 'Yorzoi' is now on BioRxiv. Here are my thoughts on this... biorxiv.org/content/10.1101/…
DesignerMicrobes Inc retweeted
Are you eligible for the NSERC Postdoctoral Fellowships (PDF) program and interested in joining Karas lab? If yes, please send your CV to [email protected] Details & eligibility: nserc-crsng.gc.ca/Students-E…
DesignerMicrobes Inc retweeted
Online now @ Cell is the yeast multicellular engineering paper from @DrFankangMeng - the fruits of his productive PhD. He developed modular synthetic biology tools to bring multicellular behaviours to yeast - adhesion, juxtacrine signalling and more. cell.com/cell/fulltext/S0092…
DesignerMicrobes Inc retweeted
What if crops could grow in poor soil, resist disease and carry more nutrients?
At #SchulichMedDent, @KarasLab is building synthetic plant genomes to make that future possible, with support from the U.K.’s @ARIA_research. schulich.uwo.ca/about/news-e…
DesignerMicrobes Inc retweeted
Excited to share that our lab is part of the @ARIA_uk Programmable Plants initiative! @WesternU @SchulichMedDent @westernuBiochem
The nine teams we’re funding in Synthetic Plants are paving the way for more productive, resilient, and sustainable plants.🌱
Discover how they'll deliver growth in agriculture for the UK + beyond: link.aria.org.uk/sp-c-x
DesignerMicrobes Inc retweeted
Together with Liyam Chitayat and Lorenzo Magni, I co-organized the inaugural edition of the Symbiogenesis Seminar Series, an online event focused on symbiogenesis.
DesignerMicrobes Inc retweeted
1/ 🌟 We've added more results to our preprint‼️ TLDR: diatom in vivo assembly, RNP delivery via electroporation, and a new PEG transformation method... (1/10) biorxiv.org/content/10.1101/…
DesignerMicrobes Inc retweeted
I am looking for a few team members to join our lab at Western University for an exciting new project focused on creating enhanced plant chloroplast genomes. I am looking to hire:
2 Postdoctoral Fellows
1 PhD Student
Additional information:
docs.google.com/document/d/1…
DesignerMicrobes Inc retweeted
Here is our newest preprint "Engineering Conjugative Plasmids for Inducible Horizontal DNA Transfer". Congratulations to @thnjaafar and all the authors. @westernuBiochem @SchulichMedDent @WesternU
doi.org/10.1101/2025.03.12.6…
DesignerMicrobes Inc retweeted
We have three openings in our lab starting as soon as April 1st :
1 Research Associate
1 Postdoctoral Fellow
1 PhD Student
The team will work on a project that aims to create synthetic plant genomes. For more information, email: [email protected] with the title "Syntato"
