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Cancer Immunometabolism - Professor - Director: Tumor Microenvironment Center - @PittTweet @UPMCHillmanCC - CoFounder:Novasenta - EiC:Immunology - views my own

Pittsburgh, PA
Joined June 2017
Photo by Delgoffe Lab (@DelgoffeLab)Photo by Delgoffe Lab (@DelgoffeLab)Photo by Delgoffe Lab (@DelgoffeLab)Photo by Delgoffe Lab (@DelgoffeLab)Photo by Delgoffe Lab (@DelgoffeLab)Photo by Delgoffe Lab (@DelgoffeLab)Photo by Delgoffe Lab (@DelgoffeLab)Photo by Delgoffe Lab (@DelgoffeLab)Photo by Delgoffe Lab (@DelgoffeLab)Photo by Delgoffe Lab (@DelgoffeLab)
Dearest gentle reader, we are delighted to announce a new story from our lab published in @Nature describing how a meal's systemic metabolic changes are interpreted by your immune system to enhance adaptive immunity. A thread 1/ nature.com/articles/s41586-0…
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Had an awesome time presenting our postprandial data on immunology and immunotherapy at #SITC26, and moderating a stellar and entertaining debate on time-of-day and immunotherapy. Tomorrow I'll be at the Prez Sesh discussing two of our 4 SITC Presidential Talks!
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KaliVir reports preliminary Phase 1/1b STEALTH-001 data at #SITC2026 71% ORR (5/7) in advanced cutaneous cancers Responses in non-injected lesions suggest potential systemic activity Read more: bit.ly/4sKNFBC #VET3TGI #SITC2026
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Congratulations to Dr John Kirkwood ( @jmkirkwood ) inducted today as a 2026 Fellow of the Academy of Immunology-Oncology @sitcancer for his pioneering research in the field of #melanoma as well as his leadership. @UPMCnews @PittHealthSci
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How the diet & microbiome may lead to immune adverse effects. Join immunologist, Dr. Abby Overacre (@OveracreLab ) later today at #SITC2026. Session 106d | Mechanisms of irAEs | 1:45-3:25 pm | North Building | 300 Level | Hall A @UPMCnews @PittHealthSci @PittDeptofMed
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Join us at Tom’s Watch Bar on Friday if you’re at #SITC26!
If you’re attending the #SITC2026 conference in Phoenix this week be sure to stop by and meet up with our team of immunologists for a casual get together on Friday, Nov. 6th. Please register using the QR code below! See you there! @gmdelgoffe @UPMCnews @PittHealthSci
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CRI STARs take the stage at #SITC26 today! 🔹 @j_eyquem (@UCSF): In vivo and Solid Tumor CAR-T Cell Therapies | 3:10 PM 🔹 @gmdelgoffe (@PittTweet): Funding Your Research Through Industry Collaboration | 3:15 PM Explore the sessions: bit.ly/3UmhtYJ
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This is an important issue. Streamlining the bottom 70% instead of 50% removes the grants that actually NEED discussion! A grant that got all 2s needs no discussion; it’s good. But a 2,3,5 (which prob would be discussed at top 50% triage) actually needs expert discussion more.
NIH study sections are in poor shape right now. Reviewing only the top third of preliminary scores lets a single reviewer eliminate a grant with no chance of recovery. This favors conservative, incremental ideas from established PIs and summarily cuts down new entrants at the preliminary stage. Far from “gold standard science,” the process has worsened under this regime even though Congress did not cut the NIH budget. A thorough investigation is needed into the political interference behind these changes and fund allocation. The prior system was imperfect and needed reform, but the outcome from the last 20 months has been wholesale destruction by imbeciles.
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What an incredible night! 🌊 Now, how about a bipartisan bill to double (protect?) the @NIH budget? Let's promote and retain our leadership in global science!
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Delgoffe Lab retweeted
Today is a top 10 Twitter day of all time
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Jean-Luc Picard remains the single most compelling vision of progressive politics I am familiar with — secular, rational, compassionate, egalitarian; a believer in progress & abundance but also duty, hard work, and a constant battle for self-improvement and improving the world.
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Delgoffe Lab retweeted
I’ll never forget how sad I was the week of May 23, 1994 when this aired. I’ll never forget how sad I am today.
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"It is possible to commit no mistakes and still lose. That is not a weakness. That is life." - Captain Jean-Luc Picard 😭
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Delgoffe Lab retweeted
Sorry we’re busy RUNNING flow! Feat our fave @BioLegend antibodies @ItzDipyaman @IshitaBaral02 @allicafferata @hannahjbum4
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Delgoffe and @OveracreLab are RUNNING FLOW this Halloween! @BioLegend
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Delgoffe Lab retweeted
they’re calling it the most Wisconsin night in history
SAUSAGE RACE AT LAMBEAU FIELD!!!!! OH MY GOD THIS NIGHT IS AWESOME
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Delgoffe Lab retweeted
I will never forget the night this aired in 1990. Our jaws were on the floor in shock. And we’d have to wait three months to see how it ended.
El millor final de temporada de la història.
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It may not surprise you that I was a Trekkie as a kid. This one hurts. I was always waiting for the next episode of TNG. Picard was a model of the best of us, the ideal human in the 24th. I met him at a convention in the 90s; I’ll never forget his warmth and love of the material.
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