PhD in Molecular Microbiology and Immunology from Johns Hopkins BSPH Postdoctoral researcher in the Casadevall Lab, Yeast enthusiast
Baltimore, MD
Joined August 2018
- Tweets88
- Following127
- Followers157
- Likes233
Pinned Tweet
Recently upgraded my Cryptococcus capsule measuring script and repackaged it as a single install file that does NOT require matlab. Still need to manually check the result images to ensure accuracy but between me and my undergrad we made 94k measurements with minimal effort.
Updated the bot a little bit so now the image preview includes the whole paper since it wasn't clear to start with that the bot makes a full paper, not just an abstract. Will next try adding figure AI and better cohesion between sections.
Quigly Dragotakes retweeted
The main message in this paper is that Cryptococcus neoformans releases proteins inside macrophages that modify host cell function. Getting this story out took almost a decade and was the work of many. @caipcoelho @dragotakes @Danfqsmith @marclrodrigues
Looking for new #virulence factors from the 🍄 Cryptococcus neoformas? The @caipcoelho lab describes how identify proteins secreted inside macrophages. One example is Yor1, shown here to affect exocytosis, capsule size, and dimension of vesicles.
academic.oup.com/microlife/a…
Finally approved for the DALLE art AI, got some things I want to try but of course I had to start with a rigorous test of its ability. Thus, I present:
"An oil painting of a minion marrying garfield"
I regret it immediately, but am impressed an AI could generate this on its own
Mk I of new pet project to make small/cheap growth curve reader. Test curve looks good, next step to test precision/replicability. Total cost < $200 though I think that can be reduced and size of p1000 tip box. Just stick it on an shaker in an incubator when you need to use it.
Figured out the power issue but I may have switched a couple sensor wires when replacing a board so I'm not sure if the well designations are accurate and can't compare conditions yet (will fix monday). Regardless, all 12 sensors appear to work fine over a 50 hour growth curve.
Quigly Dragotakes retweeted
Strong inverse correlation between the use of convalescent plasma and mortality for hospitalized patients in the USA. If causal, and preprint argues for causality, this implies many lives saved by plasma.
medrxiv.org/content/10.1101/…
A while ago I trained a bag of words to predict if a scientific article came from nature/science/cell based on title alone. It was about 85% accurate. I had it classify the titles of my AI generated papers and it thinks ~60% are good enough for NSC. So proud of my prolific robot.
Printed scopes now have motorized xyz axes and can be controlled remotely while in the incubator. Just need a stronger power supply for all the steppers.
First test run inside the incubator for a couple hours. I think the weird ridge is stray filament I didn't clean out and I think vibrations are shifting the stage, but overall looks good!
3D printed microscope designed by @OpenFlexure! This was my first test print (which went horribly) and already works great. Makes a nice ~$100 alternative to the 15k I would have had to spend on a motorized stage just to look at more macrophages each day.
3D printed microscope designed by @OpenFlexure! This was my first test print (which went horribly) and already works great. Makes a nice ~$100 alternative to the 15k I would have had to spend on a motorized stage just to look at more macrophages each day.