Building great things
Oklahoma
Joined August 2009
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darrin husmann retweeted
5 major things just happened in medicine this week:
1. A breast cancer drug more than doubled the time before the cancer started growing again in a Phase 3 trial (16.4 mo vs 6.8 mo).
2. The world’s deadliest cancer (lung) was treated with a new therapy that cut the risk of death by 58% in a Phase 3 trial.
3. Chronic Hepatitis B now has a functional cure for certain patients after accelerated FDA-approval.
4. Retatrutide put up huge numbers at a sleep medicine conference showing it cut the amount of sleep apnea events in half on the highest doses, in a Phase 3 trial.
5. The leading cause of cancer death under 50 (colorectal, here specifically rectal) now has an FDA approved therapy allowing certain patients to skip chemo, radiation, and surgery.
darrin husmann retweeted
FT comments never miss.
I don’t think I’ve read such a rational analysis of the situation we’re in for a long time.
I've been in France since 2002 and have never seen the streets so violent nor the politics so extreme. From the sacking of the supermarket on my street to the prospect of Présidente Le Pen, here's me @FT including thoughts from 2 French Nobel laureates as.ft.com/r/addcad57-0f9d-4e…
darrin husmann retweeted
That’s right you should buy some copper, I have a great supply for anyone interested
darrin husmann retweeted
An oldie but a goodie. In 1968 a bunch of entitled hippy bastards sent a letter detailing their specious demands to the Warden and Fellows of Wadham College, Oxford. This was their letter of reply, which speaks to how far the academy has since fallen.
darrin husmann retweeted
And here are some photos of the monumental statue of Arash the Archer, installed in Tehran’s Vanak Square in June 2025 ⬇️
darrin husmann retweeted
In 1826, a poor 24-year-old from Norway named Niels Abel walked into the Paris Academy with what he believed was his greatest work. Cauchy, one of the most famous mathematicians alive and one of its two referees, barely looked at it, and the paper disappeared.
Abel went home broke and sick. Thinking it was lost forever, he wrote its main idea out again from memory in just two pages and called it simply "A Theorem." He died at 26.
Two days later a letter arrived offering him a professorship in Berlin.
His idea was that sums of certain integrals over a curve always collapse to a fixed number of them, and that number measures the shape of the curve. Riemann turned this into the idea of a surface's genus, its number of holes.
For the simplest curved case, elliptic curves, it means points on the curve can be added like numbers. That addition is behind Wiles' proof of Fermat's Last Theorem and the cryptography that keeps your phone and bank cards secure today.
The lost paper was found after his death, then lost again until 1952 in Florence.
darrin husmann retweeted
A bizarre new quantum state called a Fractional Fermi Sea
Physicists in Innsbruck lined up ultracold atoms in a single row and flipped their interaction over and over from strong repulsion to strong attraction.
This should have shaken them into a random hot mess. Instead, they settled into a highly excited state with a hidden order, a new phase of matter the team calls a fractional Fermi sea.
darrin husmann retweeted
Robin Yount walked out to throw the first pitch of the World Series in Milwaukee last night wearing Bob Uecker's loud plaid sport coat.
Then he took it off and held it high toward the press box.
Underneath, he was wearing his own number 19 Brewers jersey. Across the shoulders, where YOUNT used to be, it said UECK.
Milwaukee waited forty-four years for this game. Uecker called Brewers games on the radio for fifty-four seasons. He passed away nine months before he could call this one.
So Milwaukee brought his coat to the mound.
I watched the video three times.
Where I come from, when a master falls before the final battle is reached, the next warrior carries the master's sword onto the field so his spirit can see the banners fly.
I never knew a plaid sport coat could carry as much weight as a sword. Last night, it carried all of it.
🤖 Made with AI
darrin husmann retweeted
Geoffrey Hinton once noticed that the tellers at his bank kept changing. When he asked one of them why, the teller didn't know, only that they got moved around a lot.
Hinton guessed the reason... if staff never work with the same people for long, it's much harder for a few of them to team up and cheat the bank.
That thought became one of the most useful tricks in deep learning. While a neural network trains, you randomly switch off about half its neurons at every step. No neuron can lean on a particular partner, so each one has to learn something useful on its own. The trick is called dropout, and it helped AlexNet win the 2012 ImageNet contest, which set off the modern AI boom. It's still built into many of today's networks.
darrin husmann retweeted
My father has never hugged me.
Not when I was born. Not at my graduation. Not when I left home.
That's normal for a Japanese father his age. Love is a full gas tank when you visit. A bag of oranges handed over without a word.
Last month, my friend from Texas came to dinner at my parents' house. When it was time to go, he did what Texans do.
He hugged my mother.
Then he turned around and hugged my father.
My father froze. Arms straight down. Like a soldier being hugged by a bear.
Three seconds. Nobody breathed.
After he left, my father sat at the table for a long time. Then he said:
"In America… do they do that with their fathers too?"
"Every time," I said.
He nodded. That was all.
Two weeks later, I went home for dinner. When I was leaving, my father stood up, walked to the door, and put his arms around me.
Badly. Like he was assembling furniture with no instructions.
I'm over forty. It was the first time.
He let go, looked at the floor, and said, "Drive safely."
My mother told me later he'd been practicing on the dog.
darrin husmann retweeted
Scientists found a way to flush Alzheimer’s plaque out of the brain in minutes.
Without any surgery and drugs.
Your brain has a waste-clearance network called the glymphatic system. It flushes out toxic proteins and dead cells.
But it only really activates during deep, slow-wave sleep.
If you don't sleep, the trash piles up. Over time, that buildup leads to cognitive decline and Alzheimer's.
Until today.
Researchers just published a paper proving they can manually trigger this cleaning cycle.
Without you ever going to sleep.
They used 40.68 MHz ultrashort waves (USW) beamed non-invasively into the brain.
Within 10 minutes, the brain's fluid flow rapidly accelerated.
The waves artificially synchronized the neurons into a Delta state, the exact frequency of deep sleep. This forced the brain's water channels to open and start flushing out the system.
They tested it on mice with traumatic brain injuries and Alzheimer's pathology.
The brain swelling dropped. The toxic proteins were cleared out. Cognitive deficits actually improved.
No surgery. No massive chemical interventions. Just a frequency.
darrin husmann retweeted
The 2025 Larry O’Brien Trophy spent much of last season running around town. But I can now share that the Thunder have created a home for Oklahoma City’s 2025 NBA Championship Trophy. The Trophy and its new home will debut at tonight’s home opener on the 100 level of the arena concourse.
The newly-created display is pictured below.
This will be the Trophy’s home until the opening of Continental Coliseum in two years. You can view the Trophy at all Thunder home games (so don’t worry if there’s a line tonight).
Thunder Up!
darrin husmann retweeted
This might sound crazy.
But one of the skills you NEED to learn is how to deal with a more and more illiterate society full of emotionally dysregulated people.
If you keep getting frustrated every day over how "ďumb" everything/everyone seems, the stress of it is going to wreck your mind.
darrin husmann retweeted
In 1806, John Colter was on his way home with the Lewis and Clark expedition after two years in the wilderness. He was a few weeks from civilization. He asked permission to leave early, turned around, and went right back into the mountains with two trappers.
Over the winter of 1807 to 1808, he traveled alone through hundreds of miles of unmapped country with a 30 pound pack and a rifle. He came back talking about boiling springs, steam shooting out of the ground, and the smell of sulfur. Nobody believed him. People started calling the place "Colter's Hell." He's now considered the first white man to see parts of what became Yellowstone.
Then it got worse.
In 1808, Colter and his partner John Potts were trapping beaver along the Jefferson River in Montana when several hundred Blackfeet warriors surrounded them. Potts fired and was killed instantly.
The Blackfeet stripped Colter completely naked, took his shoes, and gave him a short head start. Then they let their young men chase him.
He ran barefoot across a plain covered in prickly pear cactus, for miles, with the soles of his feet shredding. He ran so hard that blood poured out of his nose and down his chest. When he finally looked back, only one warrior was still close.
Colter stopped, turned around, and faced him. The warrior lunged with his spear, stumbled, and the spear snapped. Colter grabbed the point and killed him with it, then kept running.
He reached the river and dove under a pile of driftwood. He stayed hidden there, mostly underwater, while the Blackfeet searched the banks for hours.
That night he swam downstream and started walking. Naked, no weapon, no food, feet full of cactus. He lived on roots and covered roughly 200 miles before stumbling into a trading fort, where the men there didn't even recognize him.
And then he went back out trapping anyway.
After a few more close calls, he finally quit, moved to Missouri, got married, and died a few years later. Of all the men on the Lewis and Clark expedition, he's the one who never wanted to leave the frontier.
darrin husmann retweeted
Mark Daigneault said that when the Nuggets subbed their starters out with 1:43 to go, Shai Gilgeous-Alexander said it was the right thing for him to sub out too, even at the cost of his 141-game streak of 20+ points.
Shai's reason why: "You always treat the game with respect."