@febos41

Group Leader, Laboratory of RNA Algorithms @IMol_Institute; Ex Researcher @IIMCB_Poland & @EMBO Postdoctoral Fellow

imol.institute/leaders/baulin-group/
Joined October 2010
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We’ve just released a new SQUARNA preprint: doi.org/10.64898/2026.06.30.… Alongside it, we are launching the LaRNAl Platform: larnal.imol.institute/ #RNA #SQUARNA #LaRNAl #LaRNAlP #2D #Structure #Prediction #Bioinformatics #StructuralBiology #ComputationalBiology #Algorithms
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Eugene F. Baulin retweeted
Danny IncaRNAto@incaRNAtolabOct 22
RFviewJS v1.2.0 for #RNA secondary structure visualization is out! This release features many fixes and new features. Particularly, we introduced Outline mode, useful for example to generate review-ready pictures of large multi-domain RNAs. github.com/dincarnato/RFview…
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Eugene F. Baulin retweeted
Cambridge RNA Club@CambridgeRNAOct 16
Save the dates for this course!!
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100% recommend. Feel free to reach out with any questions.
IMol@IMol_InstituteSep 29
Establish your independent research group in a dynamic, international environment with access to core facilities and modern instrumentation. If you have a strong publication record and an ambitious research program, check out the details! 🔗 Apply now: euraxess.ec.europa.eu/jobs/4…
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Eugene F. Baulin retweeted
Dmitry Penzar@dmitrypenzarSep 22
🧬 EPIC is open: the Eukaryotic Promoter and transcription Initiation prediction Challenge. The goal: predict where, and how strongly, RNA Pol II starts transcribing, from nothing but DNA sequence. At single-nucleotide, strand-specific resolution. epic.autosome.org 🧵 1/7
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On Tuesday, September 22nd, at 18:00, I will participate in the 30th Warsaw Science Festival with my interactive lecture "Magic Algorithms and RNA Molecules" (in English). Come to @IMol_Institute (Warsaw, ul M. Flisa 6) and join me! Details here: festiwalnauki.edu.pl/spotkan…
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In the era of AlphaFold, even AI struggles to crack the mystery of ribonucleic acid, one of the trickiest biological macromolecules. Its sequence is written in just four letters - A, U, G, and C - yet it folds into an astonishing variety of shapes.
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We’ll discover how computational algorithms help us unravel the nature of RNA, take a look at the building blocks of its 3D structure, and step into the shoes of RNA structure predictors.
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Eugene F. Baulin retweeted
Danny IncaRNAto@incaRNAtolabSep 4
RFview 1.1.7 for #RNA secondary structure visualization is out! Check it out: github.com/dincarnato/RFview…

Release RFview v1.1.7 · dincarnato/RFviewJS

RFview v1.1.7

github.com
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Das Lab@RDasLabAug 17
Finally, 3D #cryoEM structure of a nucleotide polymerizing #RNA that copies #RNA to #RNA: tC19z, evolved at LMB MRC 15 y ago! biorxiv.org/content/10.64898… @Szokoli_Deni Jason Hingey, Dan Haack, Vivian Wu @nickspellmon @navtejtoor @HHMIJanelia
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Kengo Sato
@stkngJul 17
See you next time! #benasque
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The LaRNAl Platform currently provides a web interface for SQUARNA, enabling analysis of individual RNA sequences with beautiful 2D visualizations powered by RFviewJS (github.com/dincarnato/RFview…) by @incaRNAtolab and RNAcanvas (github.com/pzhaojohnson/rnac…).
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More tools from the lab will be integrated into the platform soon, including R3FOLD, our upcoming RNA 3D structure prediction method, expected in late 2026. Feedback and discussion are very welcome, and stay tuned for more!
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Many thanks to @MaxSerdakov (@IMol_Institute), Grigory Nikolaev, Davyd Bohdan, and Janusz Bujnicki (@IIMCB_Poland), and of course @EMBO and @NCN_PL!
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It also integrates structural restraints and chemical probing data and can identify Rfam templates, G-quadruplex patterns, and even protein-binding motifs!
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The method features multiple algorithmic variants, including the Nussinov algorithm, which shows strong performance with our scoring scheme, and the Edmonds algorithm, a polynomial-time method for pseudoknot prediction (yes - it’s not NP-hard under base pair maximization!).
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SQUARNA is an RNA 2D structure prediction method based on a variant of the base pair maximization framework. It supports both single-sequence and alignment-based prediction and can handle pseudoknotted structures as well as alternative conformations.
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Feeling grateful and motivated for the work ahead!
IMol@IMol_InstituteJun 26
Congratulations to Prof. Eugene Baulin on receiving the prestigious @MNiSW_GOV__PL Scholarship for Outstanding Young Scientists! At @IMol_Institute we wish you continued success and many more groundbreaking discoveries!
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