Junior Research Group Leader working on clonal #hematopoiesis, #leukemia #epigenetics and #cancer cell biology. Views are my own.
Joined August 2020
- Tweets320
- Following361
- Followers467
- Likes794
Pinned Tweet
I am overly honored to be included into the Emmy-Noether Programme by @dfg_public. Looking forward to expand my group @MHH_life and explore #chromatin features underlying clonal competition in #hematopoiesis. Incredibly grateful for all the support @FlorianHeidel @Armstrong_dfci
Florian Perner retweeted
On my way home from #EHAReCon2026 in Helsinki having caught up with old friends, met fantastic new colleagues and bright trainees, learned new things and now full of new ideas! Thanks @EHA_Hematology!
Florian Perner retweeted
Just published:
On behalf of the European LeukemiaNet, an international expert panel led presented the 2025 update of the management recommendations of chronic myeloid leukemia #CML in the journal LEUKEMIA @LeukemiaJnl open access.
nature.com/articles/s41375-0…
Very greatful to be able to contribute some of our work to this great story highlighting KAT6/7 inhibition as a therapeutic strategy in MLL-dependent leukemias. Great teamwork with @MAF_Dawson @Armstrong_dfci and my lab @mhh_life.
Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia - by
@ShellainaGordon @florian_perner, @Armstrong_dfci, @MAF_Dawson @TheDawsonLab
et al. doi.org/10.1158/2159-8290.CD… @PeterMacRes @DanaFarber
Congratulations Mark! This is fantastic news. Very well deserved!
Incredibly humbled & grateful to @ASH_hematology for the honour of the William Dameshek Prize. A recognition that belongs to the awesome scientists I have the privilege of working with every day in @TheDawsonLab @PeterMacRes @GenCancerCentre
It was a great pleasure to work together with you guys and it is fantastic to see this coming together so nicely after such a long time working on this topic.
Definitely a good starting point for further clinical development ans fundamental mechanistic follow up questions...
Congratulations to @ShellainaGordon @florian_perner on this exciting study which was a fantastic collaboration between @Armstrong_dfci and @TheDawsonLab @PeterMacRes @GenCancerCentre - we hope to see this clinically translated soon!
aacrjournals.org/cancerdisco…
Florian Perner retweeted
Wonderful presentations at EHA Congress from ISEH and @EHA_Hematology speakers. Don't miss the next joint session with @florian_perner and Zuzana Tothova at #ISEH2025🏯. Register now iseh.org/2025Registration
Joint @ISEHSociety @EHA_Hematology symposium highlighting outstanding basic/translational research on genetic and epigenetic programming during disease evolution in AML
Florian Perner retweeted
🎥 In an #ISAL2025 interview, @florian_perner provided valuable insight into the mechanisms of resistance to menin inhibitors in AML and strategies to overcome resistance.
Click here to watch:
👉 ow.ly/1spW50VuyyN 👈
#AMLsm #Leusm #Leukemia #HemOnc #ISAL25
Florian Perner retweeted
NOW ONLINE!
This review explains how targeting the KMT2A gene, a key driver in aggressive #Leukemias, with Menin inhibitors like Revumenib is showing promise. Also presented as a talk at the IJC Symposium on 14-Jan by @florian_perner
🔓➡️ doi.org/10.1002/ijc.35332
@uicc
Florian Perner retweeted
NOW ONLINE!
New review by @florian_perner et al. focuses on how targeted epigenetic drugs, like the emerging SWI/SNF‑focused compounds, are reshaping #CancerTherapy. Also presented at the IJC Symposium on 14-Jan by Prof. Michael Lübbert
🔓➡️ doi.org/10.1002/ijc.35389
@uicc
Florian Perner retweeted
Yesterday, @florian_perner spoke to us on menin inhibitors in AML - from the approval of revumenib, managing side effects, strategies to overcome resistance, and more!
The full interview will be on VJHemOnc.com soon!🎥
#AMLsm #Leusm #HemOnc
Florian Perner retweeted
Really happy to share that our review and analysis of ongoing clinical trials of ADCs for patients with breast cancer brain metastases is out now!
@IlanaSchlam @drsarahsam @nlinmd @PTarantinoMD @stolaney1 @dradityabardia
A thread of salient points & ideas of this article 🧵:
New review - ADCs for the treatment of breast cancer brain metastases (*pre DB12)
journals.sagepub.com/doi/10.…
@stolaney1 @drsarahsam @nlinmd @PTarantinoMD @DFCI_BreastOnc
Congrats Ben! This is great news!
We are delighted to celebrate Dr. Laurie Glimcher @LGlimcherMD , a valued member of our board, for her remarkable tenure as President and CEO, now President Emerita, of @DanaFarber. We also look forward to continued collaboration under the new leadership of Dr. Benjamin Ebert, a core member of our Targeting Clonal Hematopoiesis to Prevent Acute Myeloid Leukemia TeamLab. Exciting times ahead for radical collaboration!
Read more here: dana-farber.org/newsroom/new…
#Leadership #CancerResearch #DanaFarber #RadicalCollaboration
Congratulations Mark and @TheDawsonLab. Is is a very cool approach!
Our latest paper from @TheDawsonLab - huge congratulations to @HenriettaHolze & @DaneVass who led this work - hope the lineage tracing / barcoding community find this helpful cell.com/cell-reports-method…
Thanks so much @iCAN_Finland for inviting me. I am looking forward to connect with colleagues and students in Helsinki!
Welcome Dr. @florian_perner to Helsinki - and welcome all to the seminar he is giving on April 17! Join us at Biomedicum or online 💻
For more information on the speaker and the student get-together after Perner's talk, and the link, see ➡️
ican.fi/news-events/ican-sci…
ALT iCAN science seminar series, Wed 17.4. at 13.30-14.30. Biomedicum 1, Seminar room 1-2. Targeting oncogenic chromatin complexes: from mechanistic discoveries to clinical application. Dr. Florian Perner, Hannover Medical School. Department of Hematology, Hemostaseology, Oncology and Stem Cell Transplantation. Logos of iCAN, HUS and UH. Photo of Dr. Perner
Florian Perner retweeted
Job opportunity for an enthusiastic research assistant! Work on an exciting wet lab project investigating cancer in Diamond-Blackfan anaemia syndrome. Based in London @ImperialImmuno with excellent collaborators in U.K and beyond..
Florian Perner retweeted
Very excited to share our new paper on how mutations in SWI/SNF chromatin remodeling complexes alter chromatin dynamics and immune cell-fate to drive lymphoma, online now in @Cancer_Cell.
authors.elsevier.com/c/1ijJ0…
More details in the thread below.👇 🧵 1/n
This is absolutely amazing!
Congrats and thanks to the authors for creating this unique resource!
Excited to see our paper "Decoding Chromatin States by Proteomic Profiling of Nucleosome Readers" out in @Nature!
rdcu.be/dAv5S
Explore our data on how epigenetic modifications modulate protein binding to chromatin with MARCS marcs.helmholtz-munich.de/
Details below 👇
Florian Perner retweeted
Publication alert ! Paper from helmholtz-munich.de/en/ife in @Nature
How complex epigenetic modification signatures regulate genome function. With interactive online resource marcs.helmholtz-munich.de/ Big data ! @epigeneticsHMGU @HelmholtzMunich
nature.com/articles/s41586-0…
Florian Perner retweeted
Menin dependence: UBTF-ITD AML joins the club
ow.ly/8qCS50QCe9R #myeloidneplasia
