Greg Durm (@gdurm) header
Greg Durm (@gdurm) profile picture

Medical Oncologist in lung and head and neck cancer at Indiana University. Views are my own, unless they aren’t. Notre Dame, IUBB, Colts, and Reds. #LCSM

Indianapolis, Indiana
Joined May 2009
Photo by Greg Durm (@gdurm)Photo by Greg Durm (@gdurm)Photo by Greg Durm (@gdurm)Photo by Greg Durm (@gdurm)Photo by Greg Durm (@gdurm)Photo by Greg Durm (@gdurm)Photo by Greg Durm (@gdurm)Photo by Greg Durm (@gdurm)Photo by Greg Durm (@gdurm)Photo by Greg Durm (@gdurm)
Great work Ben and the whole sarcoma team!
Sharing our experience with combination ICI at IU including some ultra-rare sarcomas with good response. Many patients with sarcoma do not derive significant benefit from combination IO, but for those who do responses can be durable. Biomarkers are needed.
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Greg Durm retweeted
Excited to continue to see this workshop grow each year. A great opportunity for fellows and early faculty, focusing on ways to fund investigator initiated trials. Applications currently open for next cohort - link in article! aaci-cancer.org/News-The-Jam…
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What are plenary sessions for ASCO 2026 ? Titles are just out Watch out 🙂👇 @ASCO #asco2026 @Alfdoc2 @APassaroMD @dr_yakupergun @OncBrothers @OncoAlert @MedwatchKate @FordePatrick @DrJNaidoo @MyriamChalabi @DrChoueiri
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Terrific dinner with colleagues and friends before the @IndianaUniv Lung Cancer Symposium! Thanks to Dr Durm @gdurm and IU for the invitation and being such wonderful hosts! Looking forward to a day of learning tomorrow! #lcsm
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New #JITC article: Randomized phase II study of consolidation immunotherapy with nivolumab and ipilimumab or nivolumab alone following concurrent chemoradiotherapy for unresectable stage IIIA/IIIB non-small-cell lung cancer (NSCLC): Big Ten Cancer Research Consortium LUN16-081 bit.ly/44WS2xZ @gdurm @HirvaMamdani @SalmaJabbour1 @AparGanti @ShadiaJalal @DrJNaidoo @maryjofidlerMD @LealTiciana @DrLFeldman1
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Greg Durm retweeted
Dr. Anita Turk discusses Advances in Biomarker Based Management in Mets Colorectal Ca @IUCancerCenter @IUHemOnc @anita_turk
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Dr. Rebecca Hassoun presenting outcomes with salvage high dose chemo and transplant in relapsed GCT based on radiographic vs tumor marker progression @rebeccahassoun @IUCancerCenter @IUHemOnc
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Greg Durm retweeted
Indiana University reception at #ASCO2025 . Proud to work with a fantastic group of past, present, and future colleagues @IUCancerCenter @IUHemOnc @IU_UroOnc @rabonour1 @ChrisSweens1 @Noah_Onc @ASCOPres @ahmadalhader @gdurm @hannawants2ELCN @JenSchwartzIUSM
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Why do people get ALK+ lung cancer? Why do some respond well to treatments and others less so? How can we better treat this disease? Lung cancer research is not just about answering these key questions, but about hope. It's why Dr @AngelQinMD believes #MoreResearchMoreLife.
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ctDNA+ in consolidation IO trial (BTCRC 16-081) associates with outcomes in stage III unresectable NSCLC @JTOonline: - Tumor-informed ctDNA MRD analysis post CRT, C2D1 IO, & post 6m of IO - ctDNA+ assoc with ⬇️PFS at all timepts @OncoAlert @gdurm #LCSM jto.org/article/S1556-0864%2… – at Dublin City, Ireland
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When you’re given a platform, you use it. Women: You can be great mothers and have successful careers. These are not mutually exclusive. Huge thanks to the UCSD Medical School graduating class for inviting me to speak this year! #womeninmedicine
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LAURA Trial receives a well deserved huge applause by the audience. Huge benefit in PFS (39 vs 5.6 mo, HR < 0.2. OS still immature and 81% crossover. STAGE III EGFR+ NSCLC INCURABLE? BRAIN RMN BUT NO PET-CT required at baseline. #ASCO24 @LeciaSequist
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Having seen LAURA, Dr Jayakrishnan presents retrospective ALK+ unresectsble st3 outcomes by consolidation Rx ost. Chemo-RT. ALK TKI rwPFS huge va no consolidation. Translates to OS benefit. Reinforces @LeciaSequist message that TKI consolidation important for AGA NSCLC #ASCO24
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#ADRIATIC - new standard of care in #SCLC, where we have not seen an advance in >2 decades. Truly historic data with use of immunotherapy consolidation #LungPlenary @DavidRSpigel @LaurenByersMD @ASCO #ASCO24 @OncoAlert
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CROWN results from #ASCO24 @JCO_ASCO: phase III 1L lorlatinib vs crizotinib in #ALK NSCLC. With 5y median f/u, median PFS not reached. 5y PFS rate 60% with lorlatinib (8% with crizotinib), median time to intracranial progression NR vs 16.4m (HR 0.06). ascopubs.org/doi/10.1200/JCO…
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KRYSTAL-12: Adagrasib vs Doce in KRAS G12C ✅ ⬆️ PFS HR=0.58 ✅ ⬆️ ORR 32 v 9% ✅ ⬆️ icRR 24 v 11% ❗️29% crossover ❗️⬆️ dose reduction, interruption + SAE 🤔 PFS benefit still modest 🤔 OS should be primary EP 🤔 CNS activity important 🤔 Toxicity significant #ASCO24 #LCSM
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POP QUIZ: Is this a waterfall plot for a new lung cancer TKI? Nope…SEZ6 ADC for Relapsed Small Cell Lung Cancer (and other NECs). #SCLC #LCSM. @MDAndersonNews Thank you to the study team and all of our investigators, patients and families. @ASCO #ASCO24
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Olomorasib (G12Ci) + Pembro, Ph1b ✅ ORR = 77% (1L), 40% (2L+) ✅ Irrespective of PD-L1 🔺 Gr3 AE = diarrhoea (13%), liver (6–8%), pruritis ❓Liver tox shortlived 🤔 Encouraging activity 🤔 Ph3 data needed 🤔 Severe tox in other immuno combos not seen here 👍 #ASCO24 #LCSM
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