CTO & COO @Alchemy | Alumni of Stripe, Google, Startups.

San Francisco, CA
Joined May 2008
Guillaume Poncin retweeted
World’s most valuable bank now on @ethereum @jpmorgan deposits powered by @Alchemy How it works: JPM Coin represents dollars deposited at JPMorgan. Approved institutional clients can move those dollars on Ethereum around the clock—to pay each other or buy tokenized assets. Think of how stocks went from paper certificates to electronic trading. The shares stayed the same; moving them became easier. This is a similar shift for bank deposits: the dollars are still at JPMorgan, but Ethereum becomes a network for moving them.
JUST IN: JPMorgan announces it is bringing JPM Coin to Ethereum, allowing institutional clients to transfer U.S. dollar deposits in seconds, 24/7.
6
7
1
39
1,696
we just made @brexHQ’s Top 25 Fastest-Growing Software Vendors - only blockchain company on the list! the next generation of software is getting built onchain 📷
Fastest growing startups per Brex data
37
13
1
69
9,131
Guillaume Poncin retweeted
Fastest growing startups per Brex data
28
39
41
426
129,089
Proud to support @CashApp as they scale stablecoin money movements! Verifying transactions and continuously reconciling ledger state across EVM + Solana means a simple balance update can reach users within seconds. Great engineering by the teams making it work!
📱 .@CashApp put stablecoins in front of 59M+ people. 🤫 None of them have to think about a blockchain. 🔁 3.5M+ reconciliation checks/day 📲 ~360K settlement events/day 🔗 EVM + Solana Take a look 👇
2
3
12
693
Guillaume Poncin retweeted
Crypto products in Northeast Asia now up to 8x faster ⚡️ @Alchemy powers more API calls than Google does searches All of those tokenized stocks, stablecoins, RWA, memes now loading before you can blink in the most active crypto region of the world.
86
17
33
113
17,112
Thanks for having me on the pod @MichaelWaitze! Let's check back in and see where agent usage is at SF Tech Week 2027
Agents now drive more than half of traffic on Alchemy, and serving them has meant rewriting nearly everything, says @gponcin, CTO and COO at @Alchemy, a blockchain developer platform. Agent usage does not follow human patterns. Humans rarely work at 2 a.m. or on weekends, but agents do. Trading agents expect the platform to be available around the clock, with latency under 10 milliseconds on everything. To meet that, Alchemy has changed the way it operates. The goal is that engineers are not woken at 3 a.m. because something broke, so most interventions are now automated. Guillaume describes the change as a complete rewrite. Alchemy is rebuilding component by component, starting with the operational ones. That covers customer support, incident handling and the maintenance of blockchain nodes, which have already shifted to fully automated. The same approach applies to making the platform easy for agents to address, including Model Context Protocol and API design. Alchemy is going back to first principles and asking what agents actually want from the platform.
1
1
5
254
Guillaume Poncin retweeted
Agents now drive more than half of traffic on Alchemy, and serving them has meant rewriting nearly everything, says @gponcin, CTO and COO at @Alchemy, a blockchain developer platform. Agent usage does not follow human patterns. Humans rarely work at 2 a.m. or on weekends, but agents do. Trading agents expect the platform to be available around the clock, with latency under 10 milliseconds on everything. To meet that, Alchemy has changed the way it operates. The goal is that engineers are not woken at 3 a.m. because something broke, so most interventions are now automated. Guillaume describes the change as a complete rewrite. Alchemy is rebuilding component by component, starting with the operational ones. That covers customer support, incident handling and the maintenance of blockchain nodes, which have already shifted to fully automated. The same approach applies to making the platform easy for agents to address, including Model Context Protocol and API design. Alchemy is going back to first principles and asking what agents actually want from the platform.
2
4
1
4
637
Developer activity as true measure of chain popularity.
Introducing Chain Rankings The first real view into the crypto ecosystem. Token prices can be manipulated. Onchain volumes faked. Developer usage is the only real metric. Despite the market crashing 30%+, ecosystem activity is up 5x in 2 years 👇
2
6
625
Guillaume Poncin retweeted
Big upgrade: Your agent can now use your @Mastercard with spend controls & audibility on @agentcardai Excited to partner with the incredibly tech forward team @Mastercard. Stay tuned for more 👀 @WSJ link below
69
24
2
116
2,548
Guillaume Poncin retweeted
AI agents are moving from making recommendations to completing transactions. We are helping build the trust, authorization, and control frameworks needed for trusted agentic commerce through Agent Pay, Verifiable Intent, and collaborations like AgentCard with @Alchemy Photo credit: Michael M. Santiago/Getty Images Hear more from @JornLambert in The Wall Street Journal: wsj.com/tech/ai/mastercard-i…
50
50
19
285
31,780
Really excited to be partnering with Mastercard on this project!
1
6
505
Excited to support builders on @Arc mainnet on @Alchemy. High performance RPC, Websockets, Data APIs, Gas Sponsorship, etc. DM if you need help!
1
7
261
Guillaume Poncin retweeted
Incredible to see the surge in new dev teams building on Robinhood Chain. The ecosystem is expanding by the day. If you’re building on the chain, we want to hear from you.
Most people won't realize it for 6 months Crypto going mainstream - 3.1x growth in new dev teams vs 1yr ago @RobinhoodCrypto stock tokens driving the surge
257
49
24
677
341,319
Guillaume Poncin retweeted
At @Alchemy we really do earnestly believe blockchains will not kill all humans. I personally think it’s <.01% chance within the next decade.
Jacob is correct here—we really do earnestly believe AI could kill all humans! I personally think it is >10% within the next decade. I believe Anthropic is trying its best, but we do not yet have a plan to solve alignment for superintelligence and are not clearly on track to.
5
2
41
3,363
Guillaume Poncin retweeted
“Running both a validator and RPC infrastructure on Stellar will give us visibility into the network that most teams building on top of it don’t have. That’s useful for issuers moving real-world assets onto Stellar, because they need the execution layer to be reliable before pricing or trading ever becomes a question. Pairing that with a standardized data layer like RedStone’s is what lets those assets actually get used in DeFi.” — @gponcin, CTO of @Alchemy
1
2
15
526
Guillaume Poncin retweeted
😱 "Don't worry, just give me your money." ...that's what agentic commerce sounds like to a lot of people. 87% of payments leaders say trust is the biggest barrier to agentic payments (not the rails). So before you hand an agent a wallet, ask this question 🧵
6
4
1
11
3,656
Congrats to @tempo on the ATH! Nearly 15% of all volume since launch moved in a single week 🤯 Everyone knows stablecoin rails are becoming production infrastructure for global money movement, but this pace, this summer, is massive! Proud that Alchemy powers Tempo builders with reliable RPC. 💪
Tempo just hit an all-time high in weekly stablecoin transfer volume. More than $175M moved on Tempo last week, bringing cumulative volume above $1.2B since launch in March. Enterprises are increasingly bringing payments infrastructure onchain.
8
4
1
25
4,810
Guillaume Poncin retweeted
Launch to #2 most used chain in 14 days 🤯 well done @RobinhoodApp @vladtenev @JohannKerbrat & team!
24
16
7
239
52,522
Proud of the team - constantly iterating and tuning to shave off every last millisecond of latency, use-case by use-case. Every so often we hit big wins, like this one :D
today we're rolling out a 6-10x speed up for the entire crypto ecosystem - custom hardware - CPU optimization - globally distributed data centers + custom edge proxy eth_calls at latest now blazingly fast after powering trillions of API requests & trillion of dollars for @jpmorgan, @Fidelity, @RobinhoodApp, @Polymarket we're now at the level of micro optimizing custom hardware to get the next level of performance
6
10
544