William Green (@greenwilliamd) header
William Green (@greenwilliamd) profile picture

William Green

@greenwilliamd

Nutrition | Immunology | Metabolism | UNC-Chapel Hill | Former Davidson Wildcat

Joined December 2012
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  • Followers78
William Green retweeted
Alec Plotkin (@alecplot) profile picture
Alec Plotkin@alecplotMar 3
🕰️🚆🦠 Excited to share our new preprint: “Optimal transport fate mapping resolves T cell differentiation dynamics across tissues”! We use OT to infer realistic CD8 T cell differentiation and migration trajectories from scRNA-seq timecourses. biorxiv.org/content/10.64898… 1/
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Amazing work by talented graduate student @Pratt__Brandon and team from the @JJMilnerLab @HKayChung1. Be sure to check it out how they devised a way to unlock the therapeutic potential of CD8 T cells!
bioRxiv Immunology (@biorxiv_immuno) profile picturebioRxiv Immunology@biorxiv_immunoJan 8
Latent Regulatory Programs Generate Synthetic T Cell States with Enhanced Therapeutic Potential biorxiv.org/content/10.64898… #biorxiv_immuno
Latent Regulatory Programs Generate Synthetic T Cell States with Enhanced Therapeutic Potential

Latent Regulatory Programs Generate Synthetic T Cell States with Enhanced Therapeutic Potential

Transcription factors (TFs) govern cell fate through coordinated gene-regulatory networks, yet the full potential of these networks to generate non-native, therapeutically advantageous cell states in...

biorxiv.org
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Latent Regulatory Programs Generate Synthetic T Cell States with Enhanced Therapeutic Potential biorxiv.org/content/10.64898… #biorxiv_immuno
Latent Regulatory Programs Generate Synthetic T Cell States with Enhanced Therapeutic Potential

Latent Regulatory Programs Generate Synthetic T Cell States with Enhanced Therapeutic Potential

Transcription factors (TFs) govern cell fate through coordinated gene-regulatory networks, yet the full potential of these networks to generate non-native, therapeutically advantageous cell states in...

biorxiv.org
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Excited to share the first of many works out of @JJMilnerLab. Be sure to check it out! Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment: Immunity cell.com/immunity/fulltext/S…
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Free access link: sciencedirect.com/science/ar…
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William Green retweeted
Justin Milner (@JJMilnerLab) profile picture
Justin Milner@JJMilnerLab3 Mar 2022
Excited to share an open position for a Bioinformatics Scientist to work with us, @BrianC_Miller, and @BenjaminGVincen on tumor immunogenomics projects. My lab is using single-cell multimodal omics to uncover regulators of T cell activity. Please share! unc.peopleadmin.com/postings…
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William Green retweeted
Eric Topol (@EricTopol) profile picture
Eric Topol
@EricTopol10 Sep 2020
Good news: virtual elimination of a flu season in the southern hemisphere for 2020 economist.com/graphic-detail… @TheEconomist
Image from Eric Topol (@EricTopol)
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Our new paper is out! Given few high-income countries have overweight/obesity prevalence less than 70%, it is critical to consider obesity in COVID-19 vaccine development. @UNCpublichealth @uncnorc @RAIsukait @WGB_Health @meerashekar_wb onlinelibrary.wiley.com/doi/…
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1/ There are various tweets misinterpreting COVID-19 “pre-existing immunity” and making dangerous claims about herd immunity. Since many of those claims refer to our scientific papers, we will reiterate the facts. @SetteLab @ljiresearch @ScienceMagazine @CellCellPress
Image from Prof. Shane Crotty (@profshanecrotty)
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Well, it finally happened. This #ICE International #StudentBan got me back into the “organizing effective lobbying action via twitter” game. Want to make sure our lovely international students can keep their visas? Here’s how to do it: THREAD. thehill.com/homenews/adminis… 1/14
ICE tells students on visas they must leave US if schools go online-only

ICE tells students on visas they must leave US if schools go online-only

Immigration and Customs Enforcement (ICE) announced Monday that international students in the U.S. whose schools switch to online classes for the fall semester will have to leave the country or ris…

thehill.com
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Emerging COVID-19 hotspots like Chicago, New Orleans, and Indianapolis have varying degrees of hospital bed capacity to deal with the rising number of cases. Explore your local hospital bed capacity here: covidcaremap.org/maps/us-hea…
Image from Joe Morrison (@mouthofmorrison)
Image from Joe Morrison (@mouthofmorrison)
Image from Joe Morrison (@mouthofmorrison)
Image from Joe Morrison (@mouthofmorrison)
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*Critical Need* Understanding the evolving public health burden will help #FlattenTheCurve and allow those who have recovered to help others in isolation/need and stimulate the economy.
AAAS (@aaas) profile pictureAAAS@aaas20 Mar 2020
How many #COVID19 cases have gone undetected? And are those who had mild cases immune to new infections? Answering those questions is crucial to managing the pandemic & forecasting its course. New blood tests for antibodies could help. fcld.ly/brwmrwq #CoronaVirusUpdate
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For all the data scientists out there, together we will make a difference.
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Here is the speech that the country *needed* to hear from the President tonight: "My fellow Americans, the next few months are going to be hard. For many of us, harder than anything we've faced in our lifetimes.
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Profound implications considering metabolic reprogramming is highly used/promising for T2D and cancer immunotherapy
Immunometabolism Network (@ImmunoMet) profile pictureImmunometabolism Network@ImmunoMet4 Dec 2019
Shocker? Late life #metformin treatment limits cell survival and shortens lifespan by triggering an aging-associated failure of energy #metabolism bit.ly/385xRQn
Image from Immunometabolism Network (@ImmunoMet)
Emerging role of mitochondrial DNA as a driver of inflammation and diseases progression. cell.com/trends/immunology/f…
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A #keto diet -- not high-fat only, nor separate provision of ketones -- protected mice from influenza infection through induction of γδ T cells, found a new @YaleMed study: fcld.ly/fv84926
Image from Science Immunology (@SciImmunology)
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🎉Proud to announce that Jessica Soldavini is a 2019 @beardfoundation National Scholar, an honor that comes with a $20,000 scholarship. Congrats!! Read more about this year’s National Scholars: bit.ly/33PGfRk And more about Jessica's work: go.unc.edu/b2D5F
Image from UNC Health Promotion and Disease Prevention (HPDP) (@unc_hpdp)
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Our story on lactate-induced chronic inflammation is finally out on @Cell_Metabolism @ClaudioMauro6 @michelangelocrt thank you to all our collaborators @InflamAge_UoB @QMULWHRI @UofGlasgow @CRUK_BI @VersusArthritis @VersusArthritis @TheBHF @ImmunoMet that made this possible!
Image from Valentina Pucino (@ValentinaPucino)
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What’s responsible for inflammation during #influenza? @UofTsukuba researchers have revealed human myxoma resistance protein 1 as an inflammasome sensor in human respiratory epithelial cells: fcld.ly/859uuwo
Image from Science Immunology (@SciImmunology)
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