@haas_lab

... interested in fundamental questions of stem cell biology, systems immunology and single-cell technologies

 BERLIN, Germany
bihealth.org/en/research/research-groups/simon-haas
Joined November 2018
  • Tweets491
  • Following305
  • Followers2.9K
14Media
Excited to share our latest paper @NatureMethods We present a high-throughput framework to map cellular interactions at ultra-high scale – broadly applicable from whole-organism immune response mapping to personalized therapy response prediction (1/4). nature.com/articles/s41592-0…
16
108
6
525
46,483
1/4 🧬 New preprint from the lab! Can future clinical trajectories in AML already be read at diagnosis? We assembled single-cell multi-omics data from 184 AML patients across all known subtypes, linked to deep clinical outcome data. 🧵 biorxiv.org/content/10.64898…
3
13
67
4,997
more replies
3/4 We also establish a new AML classification based on leukemic stem and progenitor cell states, extending current classification systems. Together, the results show how features across biological scales combine to shape future clinical trajectories.
1
297
4/4 Fantastic work by first authors Jan Barinka, Sarah Gräßle & Magdalena Pajonk, with Simon Raffel, Lars Velten, and many clinical & scientific collaborators. A huge collaborative effort — very happy to finally share it!
183
In our new study @NatureCellBio, we identify stem cell kinetics and cellular competition as key principles underlying blood stem cell diversity. Fun collab. @MilsomMick @FloGrunschlager @Esther_RCorrea, Tamar Nizharadze,Thomas Höfer,Daniel Hübschmann (1/6) nature.com/articles/s41556-0…
1
5
35
2,476
more replies
Huge thanks to the fantastic interdisciplinary collaboration across the @MilsomMick , Hübschmann & Höfer labs — and especially @FloGrunschlager , @Esther_RCorrea & Tamar Nizharadze for driving this work forward! 🧬 @DKFZ , @BIH_Innovation , @MDC_Berlin @QMUL (6/6)
1
3
119
Another big thank to the many collaborators, including the labs of Andreas Trumpp, @AlejoFraticelli @zauggj @MikutRalf
4
114
Haas Lab retweeted
Mick Milsom@MilsomMickMay 25
How do lineage-biased HSC states relate to each other? check out: rdcu.be/fkASJ in @NatureCellBio Collab with @haas_lab @ChariteBerlin BIH & MDC; Thomas Höfer & Daniel Hübschmann @DKFZ @NCT_HD @hi_stem_lab 1st authors @Esther_RCorrea @FloGrunschlager & Tamar Nizharadze
7
25
4
86
20,108
So happy to see this finally out in @NatureCellBio! Co-led with @FloGrunschlager and Tamar Nizharadze, we show how lineage-biased HSC states are organized, how self-renewal divisions can shift HSC states, and how strongly these lineage biases are shaped by extrinsic demands.
Mick Milsom@MilsomMickMay 25
How do lineage-biased HSC states relate to each other? check out: rdcu.be/fkASJ in @NatureCellBio Collab with @haas_lab @ChariteBerlin BIH & MDC; Thomas Höfer & Daniel Hübschmann @DKFZ @NCT_HD @hi_stem_lab 1st authors @Esther_RCorrea @FloGrunschlager & Tamar Nizharadze
1
6
31
3,236
Principles of lymph node organization reveal lymphoma-induced reprogramming of stroma-derived chemokine networks and loss of tissue organization in nodal B cell lymphoma @NatureCancer @AnnaMathioudak1 @DKFZ @JoppSaile @zauggj @haas_lab nature.com/articles/s43018-0…
8
39
2,192
This work was a joint project led by Antonia Busse @KroenkeLab @haas_lab and @lab_keller. tinyurl.com/4rxnf2f5 #CIDP #CART #Myeloma

Chronic inflammatory demyelinating polyneuropathy (CIDP) after cilta-cel therapy

Blood Cancer Journal - Chronic inflammatory demyelinating polyneuropathy (CIDP) after cilta-cel therapy

nature.com
1
3
418
Breaking news! The Erasmus Hematology Lectures start again on September 1 with Marc Dawson. As Marc presents from Australia this lecture will be at 1pm CEST! All other lecture will be at 4PM CEST! Check out the complete list of speakers for 2025! Enjoy and share the news!
32
82
6,055
A cost-effective ultra-high-throughput cytometry-based framework for the detection of physical interactions between cells, along with the characterization of complex cellular landscapes @naturemethods nature.com/articles/s41592-0… nature.com/articles/s41592-0…
42
2
166
11,912
Interact-omics is a high-throughput cytometry-based framework for cellular interaction mapping. @haas_lab nature.com/articles/s41592-0…
6
26
1
94
7,781
Haas Lab retweeted
DKFZ@DKFZ7 Aug 2025
Ein Team aus Forschenden vom BIH, @MDC_Berlin, DKFZ, @hi_stem_lab & @QMUL hat eine Technologie zur Entschlüsselung der Immunzell-Kommunikation entwickelt. Damit lässt sich u.a. ablesen, warum Immuntherapien bei manchen Menschen wirken u. bei anderen nicht. t1p.de/w3v16

Wie Immunzellen kommunizieren, um Krankheiten und Krebs zu bekämpfen

Ein interdisziplinäres Team aus Wissenschaftlerinnen und Wissenschaftlern vom Berlin Institute of Health in der Charité (BIH), vom Max Delbrück Center, dem Deutschen Krebsforschungszentrum (DKFZ),...

dkfz.de
5
3
10
906
Replying to @haas_lab @IdoAmitLab
We demonstrated its applicability to: · Track CAR-T & bispecific Ab dynamics · Predict immunotherapy responses · Map organ-wide immune cell networks post-viral infection · Uncover pathogenic interactions in human disease phenotypes (3/4)
1
9
1,098
Huge shout-out to the incredible first authors Dominik Vonficht, Lea Jopp-Saile, Schayan Yousefian, Viktoria Flore & all other collaborators, esp. Daniel Hübschmann! Grateful to BIH, @MDC_Berlin, @ChariteBerlin, @QMUL, HI-STEM, @DKFZ @ERC_Research for the support. (4/4)
2
14
1,163
Load more