Karl Agger retweeted
Very elegant use of base editing by @AdityaSankar87, Kristian Heflin, and co-workers to simultaneously install K27R mutations in all 28 H3 histone alleles in mouse cells, resulting in the identification of a direct function for H3K27Me3 in Polycomb-mediated gene regulation. 👏🏽👏🏽
I invite you to read our work on using base editing as tool to elucidating histone PTM function in mammalian cells, focusing on H3K27 in mESCs
nature.com/articles/s41588-0…
Karl Agger retweeted
And now … imagine an edit-on-demand pipeline in such a setting.
This is a tractable goal for genomic medicine.
It really is.
A randomized trial of whole genome sequencing in sick newborns demonstrates its importance for changing the management of the babies and making the molecular diagnosis @JAMAPediatrics jamanetwork.com/journals/jam…
This can now be accomplished in < 14 hours
Karl Agger retweeted
I can only agree - thank you participants, speakers, co-organizers and the Novo Nordisk Foundation for making the #intestinalorganoids conference a truly amazing meeting!
Thank you participants, thank you speakers, thank you coorganisers, thank you Laila, Sophie and the Copenhagen Bioscience Conferences and thank you to the wonderful staff at Favrholm for making #intestinalorganoids 2019 a very special conference. Magical!
Karl Agger retweeted
Marianne T. Pedersen kicking off session 4 at #intestinalorganoids featuring an amazing line up.
Karl Agger retweeted
Less than a month to apply to this exiting conference on intestinal stem cells, lineage allocation, metabolism and microbiome, which we are organizing with generous support from the Novo Nordisk Foundation cph-bioscience.com/en/events…












