Luke Constable (@lukeconstable) header
Luke Constable (@lukeconstable) profile picture

Founder @ Lampa Capital

New York, NY
Joined June 2009
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What's interesting is this is the logical conclusion of how pharma execs thought about their business decades ago. Eg in Trigeorgis' Real Options (1996): "Option analysis provides a more flexible approach to valuing our investments. To me all kinds of business decisions are options.” – Judy Lewent, CFO Merck
i've been hammering this since 2015 (there are substacks, somewhere)- but the first "primitive" we will need to lose to advance biology is the idea of a pharma company as such. drug programs can be cleanly seen as baskets of risk and the platonic ideal is vanishingly asset light
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Back when I was active on Twitter (in ancient times), investors used to share their favorite recent reads. Do we still do that? A few I loved from this summer & would love to hear yours:
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Brett Gardner’s Buffett’s Early Investments. Self-recommending, but didn’t realize just how much of an activist Buffett was in those early years. Makes one think smallcap investors should be a lot more hands on than current practice… amazon.com/Buffetts-Early-In…
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Big fan of Eric & what @trytrata is building!
Trata (@trytrata) is now on FinTwit. We host anonymous buyside to buyside conversations via voice calls. We work with 125+ funds (vs. 10 in March) and receive 25-30 human-to-human calls weekly. We compile these conversations into a library of investment research. EX: Fund 1 is bullish and Fund 2 is bearish on $OPEN, they ask each other questions they want answered surrounding the key debates for anywhere between 30-60 minutes. The average fund on the platform: ~$200-400mm in AUM, 3 investment professionals, fundamental research focused. These funds use tools like Bloomberg and third-party expert networks, and have regular access to management teams. To the qualified lurkers and anon accounts of FinTwit: Request a call on any ticker (bull or bear). If we pair you, we’ll give you: 1. Access to that transcript and any transcripts on that ticker published through the end of 2026 2. Airpods
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Small life update! Planning to start writing again in the new year. Happy Holiday season to all of you.
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Luke Constable retweeted
94% of Parisians live less than 5 minutes from a bakery.
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People don't want to learn your API, so think of it as a ladder: 1. Maximize the problems experts can solve. 2. Minimize how much a novice needs to learn when they take their first step. 3. Make a smooth ladder between their first and last step. blog.sbensu.com/posts/2022-0…
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Fed's CBDC could also allow loan-level policy (instead of directly competing with commercial banks) This could be direct industry targeting for credit creation Eg climate-friendly bonds loans get a lower interest rate & a lower risk weighting
Fed's CBDC would compete directly with commercial banks. Talk about a monumental shift. Quick read if you're interested: federalreserve.gov/publicati…
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Fed's CBDC would compete directly with commercial banks. Talk about a monumental shift. Quick read if you're interested: federalreserve.gov/publicati…
Replying to @GOPMajorityWhip
CBDCs that fail to adhere to these three basic principles could enable an entity like the Federal Reserve to mobilize itself into a retail bank, collect personally identifiable information on users, and track their transactions indefinitely.
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$HOOD Q&A could make earnings calls *much* more interesting. If companies are compelled to answer these questions, we'll see a new generation of corporate gadflies. The real kicker would be if $HOOD lets questioners remain anonymous cc @sloaneortel blog.robinhood.com/news/2022…
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Next step: retail votes? We could see real social pressure coming from "70% of the $ ownership voted yes, but 85% of the retail shareholders on $HOOD voted no"
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Is there an app that records Zoom audio + video while minimizing + muting the app? There are so many calls I can't join in real time but would love to listen to asynchronously
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TIL Amazon has embedded DNS for physical mail. It’s called a “wedding registry.” This lets you send gifts without knowing the end address. They should let us send *anything* this way. Would make it much easier to send holiday cards & gifts to friends & family.
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How is TikTok live shopping not an existential threat to $PINS? It feels like QVC vs magazine ads. For comparison, livestreaming ecommerce is already a $300b segment in China. emarketer.com/content/evolut…
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Addendum to a great thread on monetizing freemium SaaS users. I've seen 2 major failure cases that would have saved me a lot of money if I'd known about them two years ago: 1. One-off low-tier account aggregation 2. Misaligned low-tier/high-tier sales forces
This quoted post is unavailable.
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@joshtarasoff gave an excellent presentation 10 years ago on inflationary vs above-inflation pricing power. Once inefficiently monetized products are fully priced, you won't see above-inflation pricing power. Highly recommend a read: dropbox.com/s/q3rktm2mup8ury…
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2. Misaligned low-tier/high-tier sales forces won't upsell the low-tier customers without being properly incentivized to do so. Look at the quota & sales comp structure. And also make sure that the low-tier product users can be directly upsold to the high-tier product.
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