Bioinformatician, Cellular Biologist, CSO @tychobio_ai @mathurindorel@fediscience.org @mathsrish.bsky.social
Berlin, Germany
Joined September 2016
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Midnight reflexion on to improve scientific evaluation beyond h-index: how about a veting mechanism with pagerank based on e.g ORCID profiles.
Each researcher can vouch for any number of other researchers. The importance of a researcher is then simply their pagerank.
If you're not calling your LLM a moron to it's face at least once a day you're not inspecting the results appropriately.
And your philosophy is "crash in prod".
the most import skill in 2026 is still being able to tell your agents "wtf is this crap, no, not like this"
if you stop doing that, you're basically fucked, despite what some devfluencers would like you to think.
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Mathurin Dorel retweeted
Learn how to think deeply about either the algorithms or the biology of a system. If you become a shallow generalist who relies on AI to handle the deep details, you will be outmoded and replaced. The latter is fashionable, but it's skipping building the real value of the PhD
Mathurin Dorel retweeted
We laughed, we cheered, we're happy for our American friends.
Now let's go back to work?
Cheat code for staying up to date with the state of the art.
Because of how rare my conditions are, researchers send me updates about what they’re studying
Oh yeah cause my blood has its own contract lmfao
When my samples are used for research, I’m supposed to be notified. I can’t veto anything or decide what scientists do with them, it’s just so I can know what my blood is being used for. Shoutout to my mom for thinking of that when I was a kid because it’s actually pretty cool
Anyway, I get these updates every couple of months and they’re ALWAYS something boring
Until today
3/x
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Mathurin Dorel retweeted
No disclosure yet on what tumor types were discovered. Given Zolgensma is administered as a single, one-time intravenous (IV) infusion, systemic exposure could reasonably target any tissue, so would be useful to know what tissues may be susceptible.
biospace.com/drug-developmen…
Just to be clear the science is cool.
But it's done very traditionally and could (should?) have originated from an academic research lab.
What probably happened is they thought they could solve the vault function, failed (science is hard TM) and salvaged what they could.
Anthropic turning into the dullest biotech ever.
Boring conservation biology stuck with early 2020s tools like there wasn't a revolution in software development in the meantime.
Is this it? Is this all you can conjure with Claude for Science?
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Anthropic turning into the dullest biotech ever.
Boring conservation biology stuck with early 2020s tools like there wasn't a revolution in software development in the meantime.
Is this it? Is this all you can conjure with Claude for Science?
🤣
I don't know what's the most hilarious between the social media science project and "our AI sucks at innovating so we basically had to babysit it into boringness".
Maybe it was collecting negative discs space data.
science.org/content/article/…
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Mathurin Dorel retweeted
The topic of Taurus missiles is a sensitive one. Let me explain why. This will be both an explanation and an answer to some skeptics who say: “We help Ukraine, but what is Ukraine doing for us?” Here is an example. The IRIS-T air defense system. An excellent German system, and we are grateful to its manufacturers. Every type of defense is important for Ukraine, but it is also important for German industry.
We have made IRIS-T the world’s number one system after the Patriot, which is an anti-ballistic system. Today, it costs somewhere between $600,000 and around $1 million to $1.5 million. That’s the result of this war. We have also helped address all the problem areas, because only in a real war can you truly eliminate the weaknesses of a particular defense system. Germany now has orders backed up for 10 to 20 years. The cost of a missile has gone up severalfold, even by tens of times. And all of this means jobs.
Why do we want to order Taurus missiles? Because when the Americans were unable to supply us with anti-ballistic interceptors for our air defense, we were left with only one option: to destroy Russian launchers. They have built entire launch sites and are killing us, while we have no way to defend ourselves. These are not civilian targets, infrastructure, or energy facilities. That is why we really wanted to order Taurus missiles. And not simply to order them, but, once again, to test them as well. It benefits both sides.
From an interview with ZDF. (3/3)
Mathurin Dorel retweeted
Warning signs she showed (and that any runner must respect):
- Sudden or escalating muscle pain beyond normal race fatigue (“Ow ow”)
- Weakness, swelling, dark (cola-colored) urine
- Nausea, confusion, or collapse
She texted pain and kept running. That decision, combined with the late-race physiologic stress, was likely decisive. Stopping, walking, or seeking medical help on course could have limited the muscle breakdown before toxins flooded her system.
Prevention is straightforward but unglamorous: progressive training (especially for a first marathon), aggressive hydration + electrolytes, never ignoring unusual pain, and knowing that “I’m fine, I’ll finish” can be the last thought a healthy young athlete has.
Mathurin Dorel retweeted
Bro, you can't fucking say openly on social media you just attempted to compromise an organizations infrastructure under your employer and full legal name
Are you actually fucking insane?? Genuinely what the fuck are you thinking???
And how the fuck does this dude know the employees name? Why did the employee openly admit "hehe ye thats me, but no mallace intended, it was my AI agent"
????? WHAT. THATS STILL A CRIME. WHAT ARE YOU TALKING ABOUT.
Mathurin Dorel retweeted
🇺🇦🇫🇷 J’étais présent, aussi, hier soir lors de la confrontation entre la police et des « manifestants » dans la région de Kyiv.
Je suis entré dans la maison où se trouvaient les hommes mobilisés.
Voici ce que j’ai vu, et ce que je peux établir. 1/🧵
Mathurin Dorel retweeted
ML4 is now open-weight! Frontier capabilities on code agents & cyber, way more efficient and compact than its Preview version three weeks ago (!) and cherry on the cake: technical report telling its epic backstory. Check it out: huggingface.co/mistralai/Mis…
In the evil looking category, Russia apparently had a star destroyer shaped base.
Next step in Poutin dressing as Palpatine.
Ukrainian drone teams should start using the resistance themes in their videos.
Our long-range sanctions have targeted the Rostov region. The Kamensky Combine, a Russian defense industry enterprise involved in missile production, was hit.
A Pantsir-S2 system and a command and staff vehicle of the S-400 Triumf system were also hit. The total value of the air defense assets struck is around $70 million.
I thank the warriors of the Security Service of Ukraine @ServiceSsu and other units of the Defense Forces for their accuracy! We are justly defending ourselves against Russian aggression and doing everything to reduce Russia’s capability to continue it.
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Mathurin Dorel retweeted
Mistral may be the most underestimated AI lab in the world.
Frontier open weight models are now a central goal. That wasn't always the case. Huge shift.
Les étudiants qui réclament la fin de parcoursup sont des incompétents qui souhaitent des places qu'ils ne méritent pas.
Apprenez des métiers manuels, ça rapporte autant voir plus et la société en a autrement plus besoin.
Tout ceci est consternant: est-ce qu'ils ont vu une fiche Parcoursup récemment ? Celle de la double licence dans laquelle j'enseigne me semble absolument limpide, voici par l'exemple... Il suffit de taper le nom de la formation et "parcoursup" sur Google.
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