Professor of Molecular Biosciences The University of Texas at Austin Opinions are my own and not the views of my employer
Austin, TX
Joined July 2014
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Jason McLellan retweeted
A potently #neutralizing and protective human #antibody with a unique antigenic footprint on #RSV and #hMPV fusion glycoproteins. Collaborative work with @McLellan_Lab @jjmousa @BonamiRachel @croweje @RHCarnahan, and others.
biorxiv.org/content/10.1101/…
Jason McLellan retweeted
Applications are open for PhD students via our ILS graduate programs. Come have fun and do great science in Austin! ils.utexas.edu/
I'm honored to receive this award and I'm looking forward to the event in September! Thank you!
Grateful to the @SAmedfound for supporting the #2024InnovationAward. Looking forward to celebrating the groundbreaking work of @McLellan_Lab in September.
Great work Cory!
Very excited to share this story about two substitutions in a sarbecovirus spike that enhance infectivity by increasing RBD availability. My first cryoEM structure was of the RsSHC014-CoV spike protein and is included in this manuscript! biorxiv.org/content/10.1101/…
Jason McLellan retweeted
Very excited to share this story about two substitutions in a sarbecovirus spike that enhance infectivity by increasing RBD availability. My first cryoEM structure was of the RsSHC014-CoV spike protein and is included in this manuscript! biorxiv.org/content/10.1101/…
It was an honor to receive this award with Dr. Holmgren and Dr. Graham. Many thanks to IVI and SK bioscience for supporting this award. I had a wonderful week and enjoyed my interactions with all the scientists. I look forward to new collaborations. Thank you Jerome!
Jason McLellan retweeted
Privileged to honor 3 prominent vaccinologists with 2024 IVI - SK bioscience Park MahnHoon Award. Thank you Profs. Holmgren, Graham and McLellan for your contributions to vaccines for global health.
Check out our pre-print describing a CCHFV glycoprotein complex in the pre-fusion conformation! We used several engineering tricks to design our final construct, GP38-GnH-DS-Gc. Great collaborative effort, led by graduate student @Eliza4Science! biorxiv.org/cgi/content/shor…
Thank you, I am honored to receive this award! I want to thank all the terrific scientists, collaborators, and colleagues who helped contribute to the development of the RSV and COVID-19 vaccines, particularly @BarneyGrahamMD. Exciting times for structure-based vaccine design!
Congrats to Dr. Jason McLellan, @McLellan_Lab, recipient of the 2024 "Building the Foundation Award," supported by @JNJNews! Dr. McLellan and his lab developed technologies leading to the 1st FDA-approved vaccine for #RSV. ow.ly/bPsG50QqtTb #RAAwards
Excited to share the pre-print describing our efforts to stabilize the HCMV gB ectodomain in a prefusion-like conformation. We and others have now routinely stabilized class I viral fusion proteins, but class III viral fusogens have been more difficult.
Structure-based design of a soluble human cytomegalovirus glycoprotein B antigen stabilized in a prefusion-like conformation biorxiv.org/cgi/content/shor… #bioRxiv
gB-C7 and related stabilized ectodomains should be helpful for isolating antibodies that bind exclusively to the prefusion conformation of gB proteins. Overall, this was a fantastic group effort led by graduate student Madeline Sponholtz with major contributions from ...
former postdoc Pat Byrne @PatByrne0 as well as Alison Lee from the @maynard_lab.