Marcelo Duhalde (@md6403) header
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On leadership, innovation, pharmaceuticals, digital health and the occasional Swiss highlight. Spreading ideas worth spreading.

Switzerland
Joined March 2011
Photo by Marcelo Duhalde (@md6403)Photo by Marcelo Duhalde (@md6403)Photo by Marcelo Duhalde (@md6403)Photo by Marcelo Duhalde (@md6403)Photo by Marcelo Duhalde (@md6403)Photo by Marcelo Duhalde (@md6403)Photo by Marcelo Duhalde (@md6403)Photo by Marcelo Duhalde (@md6403)Photo by Marcelo Duhalde (@md6403)Photo by Marcelo Duhalde (@md6403)
Idilic Swiss walks and cutting edge science. View of the IBM Nanotechnology Center #MyDayInZurich
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Marcelo Duhalde retweeted
I'm doing a podcast with Javier Milei (@JMilei) soon. 2+ hour conversation, in Spanish 😎 We'll subtitle & overdub it in English, so you can listen in either English or Spanish. Let me know if you have questions/topic suggestions.
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Acaba de pasar esto en el Congreso de los Diputados. Estamos ante el inicio de una Dictadura.
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Acabo de preguntarle a Patxi López por su plan contra los medios y ha pasado esto. Ya no puedo más. El clima dictatorial es irrespirable.
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Replying to @shellenberger
The Economist has also condemned Brazil’s banning of X
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It took me a while to fully realize the value of something my company achieved years ago, and continues to savor today. It’s one of our greatest quiet advantages, full stop. It’s not something you hear much about in business circles. In fact, I can’t remember the last time I heard anyone spend much time on the topic, or even bring it up in conversation, on a conference stage, or behind a podcast mic. There is, however, lots of discussion about achievement in business. A company can achieve product market fit, operational efficiency, influence, revenue goals, or, ultimately — and hopefully — profitability. But I’m not taking about those things. Those are the obvious things, the common talking points. And to those you can add the vanity metrics of achievement — social media followers, traffic, views, impressions, open rates, press mentions, gross this or gross that. All those are what they are, but they aren’t where it’s at. What I’m talking about is optionality. Achieving optionality is where it’s at. Optionality is a hearty mix of profit margin, small size, independence, attitude, and freedom. You’ve got to have all of it to have optionality. If a board is calling the shots, you don’t have much optionality. If your margins are thin, or non-existent, you don’t have much optionality. If the public owns a piece, you don’t have much optionality. If you’re too big to change direction quickly, you don’t have much optionality. And if you’re afraid to speak your mind and stake your point of view, you don’t have much optionality. Optionality lets you do things no one would give you permission to do. It lets you write excellent software and give it away for free if you choose. It lets you do things that don’t make sense in the current climate, but will long-term. It lets you be early while eventually catches up. Optionality is ecstasy. It’s making it up as you go, without making excuses. It’s openly changing your mind without having to save face. Optionality is equanimity, the corporate equivalent of enlightenment. So, entrepreneurs, ditch the bullshit. Abandon growth-at-all-costs. Reject conventional metrics. Scorn hollow acceptance. Instead, hunt for optionality. It's freedom. It's power. It's everything you crave, wrapped in a single, potent package. Chase it relentlessly. And when you get it, don’t let go.
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Good explanation of what makes countries more or less prosperous
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Happy Sunday! See what's on in #Zurich here: newinzurich.com/2024/01/what… #switzerland
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Esa sensación casi desconocida, la que te puso los ojos llorosos. Sabés que es? LA ESPERANZA ! #VLLC @inakiigutierrez @eltreceoficial
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Good to be back.
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First vote as a Swiss! Well 3 actually! Climate change targets & securing domestic energy supply, extension ofCOVID 19 measures when needed, implementation of minimum OECD tax rates for intl companies! Love this democracy! Not as disastrous as Brexit. Your get facts to read!
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My favorite productivity trick is deciding something is actually not worth doing.
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Today is my 32nd birthday. Over the last month, I asked several 90-year-olds what advice they would give to their 32-year-old selves. Here's the life advice everyone needs to hear:
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Anna Rossinelli, setting Zürich on fire this evening!! Live from here #mydayinzurich
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Congratulations to @demishassabis and John Jumper who have won the 2023 Breakthrough Prize in Life Sciences for the development of #AlphaFold, our AI system that solved the 50-year-old challenge of protein structure prediction. 1/
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My mom hired a writer to sit down with her and my 93-year-old grandmother to document stories from my grandmother’s childhood and life in India. My grandmother is loving it—it’s bringing her immense joy to recount these stories. We love it for the memories it will provide.
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Parents have to choose their battles. 8 fights worth picking with your kids:
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I love the Russian people. That is why I have to tell you the truth. Please watch and share.
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The world has never been more peaceful, prosperous or healthy. But if you read the news you'd think the apocalypse just happened. Here's 10 charts on why it’s never been better to be alive and what it means going forward:
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Can’t stop thinking? Write. Can’t start thinking? Read.
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Zürich cheers your gloomy days up 🥂 #MoetMoment #MyDayInZurich
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