Michael Felber retweeted
Stephen's Ruliobiology is a great and minimalistic way to show the beauty of cellular automata and evolution. Gave a talk about it to my family this weekend. Interactive slides to play with: znah.net/ruliobio
Can we finally make a theory for Darwin's "Endless Forms Most Beautiful and Most Wonderful"?
Introducing ruliobiology as a path to general theory in biology, starting with foundations for a theory of biological form
writings.stephenwolfram.com/…
Michael Felber retweeted
Some magical progress towards "magic state" in quantum!
Our @GoogleQuantumAI team has demonstrated "magic state cultivation" on physical hardware for the first time. The result is a 40x error reduction on our Willow processor vs. previous methods, achieving a state-of-the-art 99.99% logical fidelity.
It's another step towards useful, error-corrected quantum computers to help solve the hardest problems. The result is published in Science today, watch the video below to see how it works
Michael Felber retweeted
Today @TheLancet published our AMIE study with @BIDMC_Medicine, the first prospective study of patient-facing conversational diagnostics in a real clinic.
AMIE is a research system people can chat with before doctors appointments. Testing AMIE outside the lab with real urgent care patients showed how technology can help gather medical histories safely. Clinicians reported that the summaries helped them prepare for visits in 75% of cases and influenced their approach to care in more than half. AMIE’s differential diagnoses also matched the doctors’ final diagnoses 90% of the time giving clinicians more time to focus on patient care.
It’s Google’s first-ever paper in The Lancet’s main journal!
Michael Felber retweeted
Constructor Theory of Information
A physical system is capable of carrying information if it has these two counterfactual properties:
1. It can be set to any of at least two states. (The flip operation is possible, under the laws of physics.)
2. Each of those states can be copied. (The copy operation is possible, under the laws of physics.)”
So here is the reason why ‘information’ is a physical property: whether or not some system carries information depends on whether the laws of physics allow for these two transformations on that system.
If they don’t, then the system cannot carry information.
In a universe where no system had both properties, information would not exist.
So whether or not information is permitted depends on whether the laws of physics permit certain kinds of counterfactuals.
But it is not a property like having a certain colour or mass—factual properties of a system.
It is a counterfactual property, because whether a system contains information or not depends on whether those two transformations can be realised on it.
Through counterfactuals, you have arrived at the elusive connection between information and physics!
~Conjecture Institute Senior Scientist Chiara Marletto
Michael Felber retweeted
We'll be spending a lot more time trying to understand the outputs of language models. A few thoughts, tips & tricks:
Writing. Something I've had success with: Ask your LLM to explain something in ASD-STE100, it's a controlled language specification originally developed for aerospace maintenance documentation. LLMs well-versed in this language and it comes with heavy constraints on clean writing style that I often find a lot more readable. Sometimes I've tried to soften it a bit e.g. ask for "80% of the way to ASD-STE100" because the spec is quite stringent. But even better:
Diagrams / images. Instead of writing, ask your LLM to create a diagram. These can be a lot easier to process, parse, and understand. But even better:
Web pages. Ask for output "in HTML" to get a beautiful, interactive webpage. LLMs are getting really good at frontend and can create beautiful experiences, animations, etc. But even better:
Explainer videos. The output format I am most bullish on is fully custom / bespoke explainer videos generated on any arbitrary topic. Experiment with things like "Create a 3b1b style video explainer on X. Use my ElevenLabs API key for audio narration". (you'd need an API key for the latter or you can ask your LLM to find you decent free alternatives that use your local compute). This is actually starting to work!
In summary:
- As LLMs get better, they will do more and more of the legwork autonomously, and a lot more of our work will rise up the abstractions into oversight and understanding.
- Luckily, LLMs can help here too because as intelligence and code are increasingly abundant, you can ask for large, custom, discardable software artifacts (e.g. web apps, video explainers) that would have never made sense to create before. Push the boundaries here and you'll be surprised.
Michael Felber retweeted
Paper: arxiv.org/abs/2606.01444
Sustainable Bamboo Plastic:
nature.com/articles/s41467-0…
Michael Felber retweeted
Turing and Godel were replying to one of the questions that David Hilbert had asked in 1900.
Turing and Godel both addressed the problem and got the right answer.
Turing was focused on what could be done by a physical object...
Godel was focused on what can't be done by any physical object.
~Conjecture Institute Advisor @DavidDeutschOxf with @GadSaad
Michael Felber retweeted
Namely: we can explain reality with ever increasing fidelity and so come to change and control ever more of it.
There's books on this! "The Beginning of Infinity" explores the most fundamental consequences. And this book explores more still. Get it at: amazon.com/Farthest-Reaches-…
Michael Felber retweeted
Demis Hassabis: If you know the structure of a protein, the real question becomes—where will your drug bind, and what will it actually do?
That’s where the next wave of AI comes in. Not just predicting structures, but modeling interactions, outcomes, and real biological impact. At Isomorphic Labs, this is already happening—with 17 active drug programs and partnerships with giants like Eli Lilly and Novartis. The goal? Scale that to 100.
This is a fundamental shift in how medicine gets built. Instead of slow, expensive trial-and-error in wet labs, AI allows researchers to run thousands of hypotheses in silico—hundreds to thousands of times more efficiently. The wet lab becomes validation, not exploration.
Drug discovery is turning into a computational problem. Faster cycles, smarter predictions, and potentially massive breakthroughs in human health.
Michael Felber retweeted
Perplexity just became the the first Al company to truly go head-to-head with the Bloomberg Terminal...
Using Perplexity Computer (with no local setup or single LLM limitation), it was able to build me a terminal with real-time data to analyze $NVDA using Perplexity Finance:
Michael Felber retweeted
Progress!
The $100 whole human genome sequence finally reached! @ElemBio
sandiegouniontribune.com/202…
Michael Felber retweeted
Today, we’re releasing a significant upgrade to our specialized reasoning mode, Gemini 3 Deep Think.
Deep Think is built to drive practical applications, enabling researchers to interpret complex data and engineers to model physical systems through code.
With the updated Deep Think, you can turn a sketch into a 3D-printable reality. Deep Think analyzes the drawing, builds the complex shape, and generates a file so you can create the physical object with 3D printing.
This is rolling out now to Google AI Ultra subscribers. Select the "Deep Think" option in the tools menu to get started.
Learn more here: goo.gle/3MoiifF
Michael Felber retweeted
Together with author Dan Pink, I have started a new podcast series called Best Case Scenarios. Each episode asks an expert to give us their best possible good news scenario in the next 25 years. What happens if everything goes right? What is the best case scenario for say, energy, transportation, biotechnology and brain science? Those are the subjects of our first four episodes. These scenarios are not predictions, but visions of what we can aim for in order to make them real. Get them on your podcast app. bestcasescenarios.transistor…
Michael Felber retweeted
AlphaGenome is our latest & most advanced genomics model published in @Nature today including making the model & weights available to academic researchers. Can’t wait to see what the research community will do with it. Congrats to the team on our newest front cover! #AI4Science
Our breakthrough AI model AlphaGenome is helping scientists understand our DNA, predict the molecular impact of genetic changes, and drive new biological discoveries. 🧬
Find out more in @Nature ↓ goo.gle/4bXlV6y
Michael Felber retweeted
This is the 15-minute speech that got Canadian PM Mark Carney a standing ovation.
For those of you who have become inured to the bloviating meanderings of Trump, this is how real leaders talk.
World leadership is relocating.
Michael Felber retweeted
Replying to @SahilBloom
There need be no “goal”.
But if one wants to make progress don’t aim for “the truth” - aim to correct errors and create good explanations. Generate objective knowledge.
Why? Those things are all possible. Finding some Platonic, perfect Truth isn’t. Nor is it even desirable.


































