Molecular and Cellular Proteomics (MCP) | Research, perspective, technological innovation and resources, and issues in proteomics articles | Published by @ASBMB
Rockville, Maryland USA
Joined January 2013
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Molecular & Cellular Proteomics retweeted
We are pleased to present this collection of recent articles highlighting advances across the rapidly evolving field of proteomics, spanning areas such as chemical proteomics, glycoproteomics, and spatial proteomics.
➡️Explore the issue: mcponline.org/recent-advance… @molcellprot
ALT Promotional graphic for the Molecular & Cellular Proteomics virtual issue, “Recent Advances in Molecular and Cellular Proteomics.” The image features a ribbon model of a protein structure on a dark red background. MCP and ASBMB Journals logos are displayed.
Molecular & Cellular Proteomics retweeted
Our latest study @molcellprot uncovers a hidden crosslinking chemistry of lipid peroxidation! We show that an endogenous aldehyde crosslinks vicinal cysteine–lysine pairs in cellular proteins via Michael addition and Paal-Knorr condensation. #LipidPeroxidation #Crosslinking
New in MCP press| 4-Oxo-2-Nonenal Crosslinks Vicinal Cysteine-Lysine Pairs in Cellular Proteins.
Learn more:
mcponline.org/article/S1535-…
#asbmbMCP
Molecular & Cellular Proteomics retweeted
🧠 Via @MolCellProt:
Researchers at @WinshipAtEmory have developed a new proximity-labeling method to identify the proteins that interact with tau during aggregation, uncovering hundreds of tau-associated proteins linked to neurodegenerative disease.
asbmb.org/asbmb-today/scienc…
Molecular & Cellular Proteomics retweeted
Recent studies in @molcellprot “Integrating MACSPI and SILAC for Neuron Type-Specific Proteomics in Caenorhabditis elegans” by Ran et al. mcponline.org/article/S1535-… @ASBMB
Molecular & Cellular Proteomics retweeted
A recent study explores how extracellular vesicles (EVs) in the maternal environment impact embryo development in cattle. By analyzing EVs from pregnant heifers, they're unlocking insights to improve bovine reproductive efficiency: asbmb.org/asbmb-today/scienc… @ASBMB @molcellprot
Molecular & Cellular Proteomics retweeted
Check out our latestwork‼️
"Omics and Multiomics-Based Diagnostics for Invasive Candidiasis: Toward Precision Medicine" in @molcellprot
📝The paper looks at how omics technologies can be used to develop biomarkers in IC
Congratulations @VictorArribs
👇👇
sciencedirect.com/science/ar…
Molecular & Cellular Proteomics retweeted
Extracellular vesicles from pregnant cattle support embryo development better than laboratory models, highlighting their potential to improve reproductive efficiency in bovine embryo cultures.
➡️Read more about this recent @MolCellProt paper: ow.ly/imbu50Xvv33.
Molecular & Cellular Proteomics retweeted
A new @MolCellProt study maps protein-level changes across nonproliferative diabetic retinopathy, proliferative diabetic retinopathy and neovascular glaucoma — revealing biomarkers that may improve early detection and treatment: asbmb.org/asbmb-today/scienc….
Molecular & Cellular Proteomics retweeted
Overlabeling of peptides in proteomics can compromise protein ID & quantitation accuracy. N-hydroxysuccinimide tags proteins but also reacts with serine, tyrosine, & threonine, creating O-ester derivatives that complicate analysis: asbmb.org/asbmb-today/scienc… @ASBMB @molcellprot
Molecular & Cellular Proteomics retweeted
Recently published in @molcellprot “Microscaled Cell Surface Proteomics for Cryo-preserved Cells and Tissue Samples” by Thorup et al. mcponline.org/article/S1535-… @ASBMB @namude
Molecular & Cellular Proteomics retweeted
A study by Christiane Albrecht & Rona Karahoda explores how steroid hormones change during pregnancy, analyzing 51 steroids in healthy pregnancies: asbmb.org/asbmb-today/scienc… @ASBMB @molcellprot
Molecular & Cellular Proteomics retweeted
Recently published in @molcellprot “Enrichment of Cysteine S-palmitoylated peptides using Sodium Deoxycholate Acid Precipitation” by Jensen et al. mcponline.org/article/S1535-… @ASBMB
Molecular & Cellular Proteomics retweeted
Newly published in @molcellprot “Breaking Boundaries in Histone Modification MS-based Detection: A Tailored Search Strategy for Unrestricted identification of novel epigenetic marks” by Vai et al. mcponline.org/article/S1535-… @ASBMB @nesvilab
Molecular & Cellular Proteomics retweeted
🗓️Mark your calendars! Abstract submission for #ASBMB26 opens soon. Get ready to share your research with your scientific community. Deadline to submit is Nov. 17!
➡️Explore poster categories here: ow.ly/ZX9g50WYoFH.
#MakeItPossible #Biochemistry #MolecularBiology
Molecular & Cellular Proteomics retweeted
Latest publication in @molcellprot “State-of-the-Art and Future Directions in Structural Proteomics” by @LHapponen et al. mcponline.org/article/S1535-… @ASBMB
Molecular & Cellular Proteomics retweeted
From #asbmbMCP | In this article, authors examined mechanisms of action of two Hsp90β inhibitors against triple-negative #breastcancer, or TNBC, using a bottom-up liquid chromatography tandem mass spectrometry proteomics approach: ow.ly/uycU50WNPnK.
#DNARepair #Proteomics
ALT Graphical abstract of the Molecular and Cellular Proteomics paper, Proteomic analysis of Hsp90β-selective inhibitors against triple-negative breast cancer (TNBC) to gain a mechanistic insight.
Molecular & Cellular Proteomics retweeted
A new phosphonate-tagging method improves kinase inhibitor profiling, revealing off-target effects and paving the way for safer, more precise cancer therapies tailored to individual patients.
➡️Read more about this recent study published in @molcellprot: ow.ly/psIq50WNR1K.
Molecular & Cellular Proteomics retweeted
New in @molcellprot:
Absea’s ¹⁵N protein standards supported multi-peptide quantification in patient plasma (ALD panel)
LOQs per protein down to low attomole level, median CV ≈ 5.1% (normalized to heavy spike-in).
Read: mcponline.org/article/S1535-…
#Proteomics @labs_mann
Molecular & Cellular Proteomics retweeted
I know I post papers on here all the time, but this one is really special to me. For about three decades, the Hunt laboratory has spearheaded the field of “immunopeptidomics” in sequencing thousands of MHC class I and II associated peptides. @UvaChemPubs
sciencedirect.com/science/ar…
Molecular & Cellular Proteomics retweeted
A new phosphonate-tagging method improves kinase inhibitor profiling, revealing off-target effects and paving the way for safer, more precise cancer therapies tailored to individual patients.
➡️Read more about this @molcellprot paper: ow.ly/awab50WK0Ej.
#chemicalproteomics
ALT A graphical abstract of the MCP paper, "Site-Specific Competitive Kinase Inhibitor Target Profiling Using Phosphonate Affinity Tags."