David Mudge (@mudgey2) header
David Mudge (@mudgey2) profile picture

Nephrologist interested in kidneys, science, philosophy. Opinions often not my own

Brisbane, Australia
Joined May 2011
Photo by David Mudge (@mudgey2)Photo by David Mudge (@mudgey2)Photo by David Mudge (@mudgey2)Photo by David Mudge (@mudgey2)Photo by David Mudge (@mudgey2)Photo by David Mudge (@mudgey2)Photo by David Mudge (@mudgey2)Photo by David Mudge (@mudgey2)Photo by David Mudge (@mudgey2)Photo by David Mudge (@mudgey2)
This October, our team Redlands Rabbits, have committed to the Red Socks Challenge, to stand with Australians living with kidney disease. Please consider donating to support a better future for people with kidney disease. fundraise.kidney.org.au/st/1…
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This October, our team Redlands Rabbits, have committed to the Red Socks Challenge, to stand with Australians living with kidney disease. To raise awareness and help fund better care. Please donate to support a better future for people with kidney disease. fundraise.kidney.org.au/st/1…
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David Mudge retweeted
Scientists have achieved the restorative benefits of deep sleep in awake mice, without them actually sleeping. In a groundbreaking study published in Nature Neuroscience, researchers at the University of Wisconsin-Madison used optogenetics, a technique that uses light to control genetically modified neurons, to induce slow-wave “on/off” patterns characteristic of non-REM sleep in localized regions of the animals’ brains. Sleep-deprived but active mice that received this artificial stimulation performed as well on memory and learning tasks as fully rested mice. The results support the idea that specific neural activity patterns, rather than unconsciousness itself, drive synaptic restoration and cognitive recovery. This discovery suggests it may one day be possible to develop targeted therapies that counteract the effects of sleep deprivation and help treat cognitive decline in humans. [Driessen, K., Squarcio, F., Tononi, G., & Cirelli, C. (2026). Induction of cortical on/off periods in awake mice fulfills sleep functions. Nature Neuroscience]
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Time to head home
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Exercise Changes the Heart in a Way Researchers Never Expected scitechdaily.com/exercise-ch…
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David Mudge retweeted
The patterns of trigonometry
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The October edition of Kidney Kolumns is out! A unique and invaluable patient perspective on TMAs is provided by the indomitable @kamaldshah … makes for a must-read for all of us in nephrology - thank you Mr Shah for your contribution!
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Interesting study on the metabolic ceiling cell.com/current-biology/ful…
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