Aberdeen, Scotland
Joined February 2021
Excited to share our new paper in Nature Communications! We mapped how extracellular matrix (matrisome) genes shape human cortical development and how their dysregulation is linked to neurodevelopmental disorders. nature.com/articles/s41467-0…
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Researchers from the University of Aberdeen have uncovered, for the first time, how genes linked to autism and intellectual disability may influence early brain development. abdn.io/1SE @kangberglab
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Eunchai Kang retweeted
Excited to share our new paper in Nature Communications! We mapped how extracellular matrix (matrisome) genes shape human cortical development and how their dysregulation is linked to neurodevelopmental disorders. nature.com/articles/s41467-0…
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Thanks to the authors Do Hyeon, @drzamankhan @GrumpybaldProf @OliviaSoper19 and Mike Morgan. Thanks for funding from @humane_research who helped make this possible! And @BBSRC @acmedsci @The_MRC @HorizonEU. @AberdeenNeuro @aberdeenuni
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Neuroscientists at the University of Aberdeen have published a new study in Nature Communications. It maps how extracellular matrix (matrisome) genes shape human cortical development and are linked to neurodevelopmental disorders. Read the paper here: rdcu.be/ePnyU
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These organoids maintain organized neural stem cell niches, support ongoing neurogenesis, and generate hippocampus-specific neurons. We used the model to study prenatal glucocorticoid exposure, which reduced NSC proliferation and drove a precocious quiescent-like state.
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Transcriptomic and functional analyses reveal that glucocorticoid signalling enforces NSC quiescence through autophagy-linked programs, limiting hippocampal growth. @AberdeenNeuro @kangberglab
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Congratulations to @OliviaSoper19 on successfully defending her PhD thesis! 🎓👏 Thanks to @derekgarden and Kat Bowles for serving as external examiners and for their thoughtful input. #PhDDefense #Neuroscience
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Poster presentation by Do Hyeon at the anatomical society summer meeting in Oxford @anat_soc @aberdeenuni @humane_research
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Fascinating talk 💡by Dr. Muhammad Assir (@drzamankhan) on how IL-17A disrupts cortical development in a 3D ex vivo MIA model—triggering early folding, increased thickness & neuronal maturation. 🧠📚 #AnatSocSummer25 #AnatSocOxford
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Wonderful presentation by David Berg from @aberdeenuni on how using human tissue and 3D organoid modelling helps understand better the neurogenic niche of the developing dentate gyrus and its relevance in neurodevelopmental disorders 👏 #AnatSocSummer25 #AnatSocOxford
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Poster 4 by @SaraValkila , learn about her work on the human ganglionic eminences and how they are affected by maternal inflammation #AnatSocSummer25 @aberdeenuni @anat_soc
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Heartfelt thanks to my PhD supervisor, Dr. @neural_lab , and to my family, friends, and colleagues who supported me along the way. Here’s to new beginnings—and to making a difference. #Graduation #PhDJourney #LifelongLearning #Science #GrowthMindset #UniversityOfAberdeen
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Sincere thanks to Prof John Mason (external) and Dr Emilie Hollville (internal) for their expert examination and thoughtful discussion. 🧠👏 @AbdnLifeScience @aberdeenuni @AberdeenNeuro
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🎓 Congratulations to Dr Do Hyeon Gim on a brilliant PhD defense! His thesis uncovers cell-type and temporal-specific matrisome expression signatures in human cortical development and neurodevelopmental disorders. Read it here: doi.org/10.1101/2025.02.24.6…
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Including an interesting panel discussion on advantages and limitations of existing iPSC models @neural_lab. It appears, however, that there are many outstanding questions in the organoid field that require further discussions and consensus in the field.
A super first day at Stem Cell Models of Neurodegeneration 2025! 🎉 🧠
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Proud of my first PhD student Muhammad @drzamankhan who passed his viva! Great job! And thanks to Dr Theil and Dr Garden who gave valuable feedback. @AberdeenNeuro @aberdeenuni
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