Keisuke Nagao (@ngosuke) header
Keisuke Nagao (@ngosuke) profile picture

Keisuke Nagao

@ngosuke

Postdoc @UWproteindesign; PhD in Materials Science and Engineering @MIT_DMSE

 Seattle, WA
Joined January 2014
  • Tweets159
  • Following725
  • Followers508
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Photo by Keisuke Nagao (@ngosuke)Photo by Keisuke Nagao (@ngosuke)Photo by Keisuke Nagao (@ngosuke)Photo by Keisuke Nagao (@ngosuke)Photo by Keisuke Nagao (@ngosuke)Photo by Keisuke Nagao (@ngosuke)Photo by Keisuke Nagao (@ngosuke)Photo by Keisuke Nagao (@ngosuke)
Keisuke Nagao retweeted
Maxwell Kazman (@maxkazman) profile picture
Maxwell Kazman@maxkazmanOct 21
Great things come from great teams! Super excited to share rfd4-proteina.org, a step-function improvement in generative protein design! A year in the making with @UWproteindesign , NVIDIA GenAIR and the amazing @DidiKieran @nscorley and @RafiBrent! 🧵1/n
RFD4-Proteina

RFD4-Proteina

Biomolecular design through latent reasoning with RFD4-Proteina.

rfd4-proteina.org
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Kieran Didi (@DidiKieran) profile picture
Kieran Didi
@DidiKieranOct 21
Avengers assemble: 1 year BakerLab + NVIDIA GenAIR = 🔥 rfd4-proteina.org Presenting RFD4-Proteina, our latest protein design model, significantly better and faster than everything we compared against, both in silico and in the lab! 1/30
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Kota Kondo (@kota_kondo) profile picture
Kota Kondo
@kota_kondoOct 9
PhD Defense（博士公聴会）に合格し、MIT AeroAstro（マサチューセッツ工科大学航空宇宙工学科）で博士号を取得しました！ 時間はかかっても良いので、目標は一つ一つ達成していくこと。自分の無知を自覚すること。健康的な食事と睡眠と運動は譲歩してはいけないこと。腹を割って話せる友達は心から大切にすること。自分を客観視すること。自分の感受性は自分で守ること。謙虚さと周りへの感謝を忘れないこと。時間は有限であること。他人と比べないこと。大切なのは目的地でも旅路でもなくて誰と共に歩くかということ。自分の中にある先入観を認識すること。正直に生きること。柔軟に、されど筋はしっかり通すこと。を本当に本当に身をもって学びましたっ！
Image from Kota Kondo (@kota_kondo)
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Keisuke Nagao retweeted
The Nobel Prize (@NobelPrize) profile picture
The Nobel Prize
@NobelPrizeOct 7
BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2026 #NobelPrize in Chemistry to Henri B. Kagan and Kenso Soai “for the discovery of non-linear effects and autocatalysis in asymmetric organic synthesis.”
Image from The Nobel Prize (@NobelPrize)
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Keisuke Nagao retweeted
The Nobel Prize (@NobelPrize) profile picture
The Nobel Prize
@NobelPrizeOct 5
BREAKING NEWS The 2026 #NobelPrize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
Image from The Nobel Prize (@NobelPrize)
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Keisuke Nagao retweeted
Cell (@CellCellPress) profile picture
Cell@CellCellPressJan 30
Now online! AAVLINK: A potent DNA-recombination method for large cargo delivery in gene therapy dlvr.it/TQf5bn
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「リケラボ」でご紹介頂きました。これからも自分に出来ることを何とか続けていきたいと思います。今後ともどうぞよろしくお願い致します。 rikelab.jp/post/12319.html

世界初「ビゲロイ」培養に成功「サイエンス」の表紙を飾る大発見。高知大学海洋コア国際研究所 萩野恭子先生｜生物のトピックス

円石藻ビゲロイの窒素固定を世界で初めて解明し、Science 表紙も飾った萩野恭子先生。逆境の中でも研究を続けた軌跡から「探究を諦めないこと」の本質に迫ります。

rikelab.jp
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Structural basis of liver de-targeting and neuronal tropism of CNS-targeted AAV capsids biorxiv.org/content/10.1101/… #biorxiv_molbio
Structural basis of liver de-targeting and neuronal tropism of CNS-targeted AAV capsids

Structural basis of liver de-targeting and neuronal tropism of CNS-targeted AAV capsids

Crossing the blood-brain barrier while minimizing liver transduction is a key challenge in developing safe adeno-associated virus (AAV) vectors for treating brain disorders. In mice, the engineered...

biorxiv.org
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Keisuke Nagao retweeted
DMSE at MIT (@mit_dmse) profile picture
DMSE at MIT@mit_dmse11 Oct 2024
Researchers including DMSE’s Polina Anikeeva and grad student Ye Ji Kim have discovered that magnetic nanodiscs could provide less invasive brain stimulation, paving the way for stimulation therapies without implants or genetic modification. @AnikeevaLab buff.ly/4f0tYh4
Image from DMSE at MIT (@mit_dmse)
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Ubadah Sabbagh (@neubadah) profile picture
Ubadah Sabbagh
@neubadah14 Sep 2024
every night before I sleep I say a blessing to this reviewer I once got
“To my mind this is an excellent paper. The manuscript clearly describes an extensive (and very well-performed) body of work. Methods are described in appropriate detail; conclusions are well supported by the results as presented. I really have no suggestions for improvement, the paper is already of publication quality and is likely to be of significant interest to those who study the circuitry and function of the early visual system.”

ALT “To my mind this is an excellent paper. The manuscript clearly describes an extensive (and very well-performed) body of work. Methods are described in appropriate detail; conclusions are well supported by the results as presented. I really have no suggestions for improvement, the paper is already of publication quality and is likely to be of significant interest to those who study the circuitry and function of the early visual system.”

Wallace Marshall (@WallaceUcsf) profile pictureWallace Marshall@WallaceUcsf14 Sep 2024
Replying to @Edel_PLopez
seriously there is NOTHING WRONG with saying that a manuscript is fine as it is and does not need further changes! I think half the problem with peer review is that we all feel under pressure to find flaws, however minor, to show we are doing our jobs.
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Keisuke Nagao retweeted
hnisimasu (@hnisimasu) profile picture
hnisimasu@hnisimasu26 Jun 2024
Happy to announce that two papers on the bridge RNA-guided IS110 recombinase have been published in Nature! Many thanks for the wonderful collaboration with @pdhsu. nature.com/articles/s41586-0… nature.com/articles/s41586-0…
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"Shoot for the stars – maybe you'll hit the moon" George Church is a pioneer of personalized genomics and synthetic biology & has co-founded >50 companies. On the Night Science Podcast he discusses embracing outliers and taking calculated risks podcasts.apple.com/us/podcas… @geochurch
Image from The Night Science Podcast (@nightsciencepod)
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GKIDS Films (@GKIDSfilms) profile picture
GKIDS Films@GKIDSfilms29 Jun 2023
The tournament of the century is about to light up!! 🏀🔥 #SLAMDUNKMOVIE THE FIRST SLAM DUNK hits US & Canadian theatres starting July 28 in sub & dub! 🏆 Get tickets: tinyurl.com/485hn9n5

THE FIRST SLAM DUNK | Official English Teaser

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[2/3] Lead authors @ath_1910 @OrgucSirma @RuptheScientist say the flexible fibers have the potential to one day reveal links between digestive health + brain conditions like #autism + #Parkinsons disease. @ScienceMIT @MITEngineering @mit_dsme @RLEatMIT @MITbrainandcog
Image from McGovern Institute (@mcgovernmit)
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Our lab’s work on flexible neural interfaces for chronic interrogation of the gut-brain axis is now published in Nature Biotech Congratulations to Atharva, Laura @gutbrains, Sirma, and all the authors news.mit.edu/2023/unraveling…
Unraveling connections between the brain and gut

Unraveling connections between the brain and gut

MIT engineers designed a technology to probe connections between the brain and the digestive tract. Using fibers embedded with a variety of sensors, as well as optogenetic stimulation, the research...

news.mit.edu
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Keisuke Nagao retweeted
Elon Musk (@elonmusk) profile picture
Elon Musk
@elonmusk1 Dec 2022
🇯🇵🇯🇵 Congratulations Japan! 🇯🇵🇯🇵 teapaw.org/i/events/1581802544912…
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Daryl Yee (@dryeeseeks) profile picture
Daryl Yee@dryeeseeks2 Nov 2022
Wow @MIT just raised the minimum salary of postdocs to $65k a year. That’s a ~$10k increase from the previous minimum. That’s incredible! This will go a long way towards combating the rising cost of living in the Greater Boston area.
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Jaan Aru (@jaaanaru) profile picture
Jaan Aru@jaaanaru13 Oct 2022
A game changer for neuroscience: MRI with millisecond precision. Out now in @ScienceMagazine science.org/doi/10.1126/scie…
RETRACTED: In vivo direct imaging of neuronal activity at high temporospatial resolution

RETRACTED: In vivo direct imaging of neuronal activity at high temporospatial resolution

A noninvasive neuroimaging method allows direct mapping of neuronal action potentials in a living mouse brain with high resolution.

science.org
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Keisuke Nagao retweeted
The Nobel Prize (@NobelPrize) profile picture
The Nobel Prize
@NobelPrize5 Oct 2022
BREAKING NEWS: The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”
Image from The Nobel Prize (@NobelPrize)
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The Guardian (@guardian) profile picture
The Guardian
@guardian15 Sep 2022
Japanese professor wins Ig Nobel prize for study on knob turning theguardian.com/education/20…
Japanese professor wins Ig Nobel prize for study on knob turning

Japanese professor wins Ig Nobel prize for study on knob turning

Annual satirical awards laud little-known research topics such as why ducklings swim in a line formation

theguardian.com
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