Exometabolomics linking genomes with environments to understand how webs of microbes sustain biomes
Berkeley
Joined June 2014
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The Northen Lab retweeted
GPT-4 does drug discovery.
Give it a currently available drug and it can:
- Find compounds with similar properties
- Modify them to make sure they're not patented
- Purchase them from a supplier (even including sending an email with a purchase order)
An exciting new paper that elucidates mechanisms by which bacteria modulate auxins in the plant microbiome nature.com/articles/s41564-0…
Our lab, in collaboration with the Niyogi and Merchant groups at UC Berkeley, is looking for a post-doc to use the EcoBOT (eco-fab.org/), synthetic biology, and lipidomics to develop the alga, Auxenochlorella, for sustainable bioproducts.
Northen Lab researchers recently participated in the BLDAP, a high school STEM program from @BerkeleyLab through @LBNLnext. Students ran experiments using EcoFABs, and tested effects of nitrogen on plants. Learn more below! @ying_wang_19 @VlastiNovak
northenlab.org/news/northen-…
Bulk soils (or soils free of living roots) have a much greater volume and surface area than the rhizosphere. Some of our newest research compares the metabolic traits of bacteria in bulk soils vs. bacteria present in the rhizosphere of an oat plant!
biorxiv.org/content/10.1101/…
Plant-produced metabolites can have a big impact on rhizosphere microbial communities, and some of our newest research explores rhizosphere chemistry, microbiome dynamics, and abiotic stressors. Come check it out! biorxiv.org/content/10.1101/…
More research from our group has been published in @FrontMicrobiol! Learn about the design and advantages of Northen Lab Defined Medium (NLDM) in the paper "A Defined Medium for Cultivation and Exometabolite Profiling of Soil Bacteria."
frontiersin.org/articles/10.…
We have a new paper published in @FrontMicrobiol that we are excited to share! Come check out "Substrate Utilization and Competitive Interactions Among Soil Bacteria Vary With Life-History Strategies."
doi.org/10.3389/fmicb.2022.9…
The Northen Lab retweeted
🌾Responses to the same 🦠 are dynamic through ⏰️ & depend on abiotic condition i.e. nutrient status.
Latest @JXBot sudy by @kuang_weiqi @Sanow_St John P. Vogel @trentn and @MelbourneRoots
Including @BerkeleyLab @ibg2root and #JPPC @IBG2Plant @fz_juelich
N-fixing 🦠, #Herbaspirillum seropedicae, altered growth, #nitrate or #ammonium uptake, and gene expression of #Brachypodium 🌾 in the gnotobiotic syst. #EcoFAB-N. #Nitrogen fertilization and time were most important variables. #roots #phenotyping @JXBot academic.oup.com/jxb/advance…
The Northen Lab retweeted
A sweet spot in marine ecosystems rdcu.be/cMz5m
Analysis of sediment and pore water from three seagrass meadows around the world reveals an unexpected accumulation of labile carbon in the marine rhizosphere, explained by sediment chemistry.
Check out a new article by some of our researchers, "A sweet spot in marine ecosystems," published in @NatureEcoEvo:
rdcu.be/cMxCA
The Northen Lab retweeted
“#Biocrusts play critical roles in arid ecosystems,” says the Lab's Trent Northen, a biochemist studying #microbial communities. Because biocrusts cover 12% of all land on #earth, keeping them healthy is essential for the planet's health. science.org/content/article/…
Happening tomorrow!
Register at bit.ly/3udx2SW for the 12pm PST, Feb. 9 webinar on the @jgi-@EMSLscience joint proposal call. With Mary Lipton & @KHofmockel @PNNLab, Trent Northen @northenlab @LBNLBioSci @BerkeleyLab, Hugh O'Neill @ORNL and Michael San Clemens @NEON_sci. @Battelle
ALT Graphic with EMSL Learn logo in top left corner and the event date and time in the top right corner. In the center is a description of the webinar agenda. At the bottom of the card are logos for the 4 associated institutions.
Excited to share this article! A couple of Northen Lab researchers explored some of the ways microorganisms and metabolites interact.
Small partners, big impacts
This Genome Watch article highlights integrative approaches for discovering metabolites and microorganisms that improve cognitive performance.
nature.com/articles/s41579-0…
There is a new job opening at our lab! Check out the Metabolomics Associate Data Scientist position: lbl.referrals.selectminds.co…
We're excited to share one of our newest papers, where we took a look at biofilms and interactions between bacterial strains. Read the full article from Frontiers in Microbiology: doi.org/10.3389/fmicb.2021.7… #biofilms #microbiology #metabolomics
Check out our mini-conference on mechanistic ecology enabled by model ecosystems at this week's World Microbe Forum: bit.ly/2Sm1V7q
After many years of work, we've finally submitted a paper describing SIMILE a new approach for pairwise alignment of fragmentation spectra with p-value estimation that is inspired by protein sequence alignment approaches (e.g. BLAST) doi: doi.org/10.1101/2021.02.24.4… #metabolomics
The JGI Functional Genomics CSP deadline is coming up soon (Jan 31). This is a chance to access DNA synthesis, sgRNA libraries, RNA-seq, data mining, metabolomics, and Mapping TF binding sites to advance your science. See bit.ly/JGI-FG21 for more info.
The Northen Lab retweeted
Long-read metagenomics of soil communities reveals phylum-specific secondary metabolite dynamics biorxiv.org/cgi/content/shor… #bioRxiv