Evolutionary quantitative geneticist | Assistant Prof (Research) @AshokaUniversity
Joined April 2012
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My first paper as an independent young investigator on sex differences in the multivariate genetic architecture of humans got published in PNAS. We estimated the B matrix in humans which shows sexual antagonism mostly driven by testosterone. bit.ly/4bOYoSC
Anasuya Chakrabarty retweeted
Its finally out! Over 8 years of work by @aliakbari23 shows that selection was pervasive in the last 10,000 years, including for quantitative traits. This was directional selection. Simulations show background selection, etc can not produce the observed patterns.
Anasuya Chakrabarty retweeted
Ancient DNA reveals that natural selection has upregulated the immune system over the last 10,000 years biorxiv.org/content/10.64898… #biorxiv_evobio
Anasuya Chakrabarty retweeted
New work from our group developing a method to estimate the molecular heritability of longitudinal traits (e.g. disease onset, progression, or death). Many traits appear to be a genetic mixture of onset/liability and progression components. See Kodi's thread for more:
Excited to share our preprint introducing COXMM! COXMM is a Cox proportional hazard mixed model for estimating the heritability of time-to-event (TTE)/longitudinal traits. 🧵1/10
Work with @SashaGusevPosts and @sr_sankararaman.
doi.org/10.64898/2026.02.16.…
Anasuya Chakrabarty retweeted
Supporting a loved one with Bipolar Disorder involves encouraging treatment, monitoring mood swings, avoiding substance use, and promoting a healthy routine. Seek help if signs of self-harm or aggression appear. For support, call TeleMANAS: 14416.
#SupportAndCare #BipolarDisorder
Anasuya Chakrabarty retweeted
Does the gut microbiome explain variation in fitness in wildlife? Our decade-long effort to answer this question in @SI_horses suggests that it does. Out in @NatureComms today:
nature.com/articles/s41467-0…
@saikat83 @diptarupNandi @raxitdaves @joshiamitabhevo @DeepaAgashe @vishuguttal @RamrayB @minivets @steve_ramm @PKorsten
Anasuya Chakrabarty retweeted
Peer reviewed and out today in @CommsBio !
nature.com/articles/s42003-0…
Many thanks to our handling editor and our peer reviewer for helping us improve on the manuscript!
Curious about what happened to all the data that we collected as part of our initiative?
Wonder no more! We published it!📰
biorxiv.org/content/10.1101/…
🧵
📢#hiringalert Do you want to unravel mysteries of sex-difference in humans while working with cutting edge quantitative genetics?Do you have quantitative bend of mind,with interests in genetics & statistics?Apply for Project Associate-I position at NIBMG shorturl.at/eiRYZ
Project assoc position available. Do you want to unravel the mysteries of sex-difference in humans while working with cutting edge quantitative genetics? Do you have a quantitative bend of mind, with interests in genetics and statistics? Then please apply shorturl.at/eiRYZ
Anasuya Chakrabarty retweeted
An interesting and brief summary by Peter Whimsatt of Richard Lewontin's impressive scientific accomplishments, both in evolutionary biology and philosophy of biology. Worth reading:
onlinelibrary.wiley.com/doi/…
Anasuya Chakrabarty retweeted
Massive inflation in SNP-heritability estimates when including relatives:
Anasuya Chakrabarty retweeted
Curious about what happened to all the data that we collected as part of our initiative?
Wonder no more! We published it!📰
biorxiv.org/content/10.1101/…
🧵
Anasuya Chakrabarty retweeted
This was an interesting read from Plomin and Deary on the genetics of intelligence. Notably, they make five predictions about what we should expect to see from molecular data, based on their decades of experience with twin studies. Do they hold up? A 🧵:
nature.com/articles/mp201410…