Dear Readers! Take a look at the September Issue: 🔗 onlinelibrary.wiley.com/toc/… #EAACI #PAI_journal

Food allergens don't just stay in the kitchen. 🏠🥜 This letter explored the presence of #walnut, #cashew, and #peanut #proteins in household dust and their association with #sensitization in young children with #AtopicDermatitis. 🔗 doi.org/10.1111/pai.70496 #FoodAllergy #AD #PAI_journal #householddust

Not every perioperative reaction is benign. This study highlights that perioperative hypersensitivity reactions in children, although uncommon, may be severe and even life-threatening. The findings reinforce the importance of #allergy investigation after suspected reactions and demonstrate how #PreventiveMeasures can successfully reduce specific risks, such as #latex-related reactions. Pay attention to this 🔗 doi.org/10.1111/pai.70474 #PediatricAnesthesia #Anaphylaxis #PAI_journal #neuromuscularblockingagents #perioperativehypersensitivity #tryptase

From asthma to food allergy, targeted therapies are changing lives. 🌟 Advances in #biologics and small molecules are enabling more personalized approaches to pediatric allergic diseases, improving disease control and expanding treatment options for children and families. This comprehensive #review highlights where we are today and where the field is heading next. Feast your eyes on this 🔗 doi.org/10.1111/pai.70454 . #Allergy #smallmolecules #FoodAllergy #AtopicDermatitis #PAI_journal #diseasecontrol #chronicspontaneousurticaria #eosinophilicesophagitis #severeasthma

A closer look at asthma exacerbations. Distinct #epithelial and #antiviral airway signatures were identified in children with refractory #asthma during rhinovirus-associated exacerbations. 🔗 doi.org/10.1111/pai.70492 #PAI_journal #refractoryAsthma #AirwayBiology #rhinovirus

World Statistics Day 📊🌍 Behind every medical breakthrough are data that help us understand diseases, improve care, and shape better outcomes for children. Today, we celebrate the power of statistics in advancing pediatric allergy and immunology research. #WorldStatisticsDay #DataScience #PediatricAllergy #Research #PAI_journal

Air pollution can worsen #rhinitis symptoms. In this prospective study, higher exposure to PM2.5 was associated with greater symptom severity in children with chronic rhinitis. 🔗 doi.org/10.1111/pai.70493 #AirPollution #ChildrenHealth #PAIjournal #prospectivestudy #PM2.5 #chronicrhinitis #allergicrhinitis #pediatricrhinitis #Thailand

Five years later, the food allergy signal remains. Children born during the #COVID19 #lockdown continued to show low rates of food allergy at 5 years of age. The authors suggest that higher #breastfeeding rates, reduced antibiotic exposure, and structured early #allergen introduction may have contributed to this protective effect. Meanwhile, #aeroallergen sensitization increased as expected during childhood. at #pai_journal 🔗 doi.org/10.1111/pai.70477 . #FoodAllergy #breastfeedingrates #antibioticexposure #allergenintroduction #Atopicoutcomes #CORALcohort #birthcohort #environmentalexposure #hygienehypothesis #SARSCoV2

One more #JuniorMember highlight, an article from the Junior Member, Joanna Zygadlo the original article: 🔗 doi.org/10.1111/pai.70276 . #pai_journal #MustRead #EAACIJM #BacterialImmunostimulants #ImmunodeficientPatients #immunostimulants #OM85 #RespiratoryInfections #immunodeficiencies #autoimmune #ImmuneImprovements #infections #efficacy #safety #acuterespiratoryinfection #immunodeficiency #IgA #IgG

World Food Day 🌍💚 Food should nourish, connect, and empower every child. Today, we recognize the challenges faced by children living with food allergies and the importance of safe, inclusive, and nutritious food environments for all. #WorldFoodDay #FoodAllergy #PediatricAllergy #PAI_journal

Congratulations to the recipients of the PAI–APAPARI Award 2026. 🏆 This year's award recognizes three remarkable studies that have advanced knowledge in #foodallergy, #anaphylaxis, and #atopicdermatitis. Their work reflects the scientific #excellence, #innovation, and #commitment that continue to drive progress in pediatric #allergy and #immunology. Please join us in celebrating this year's #awardees and their important contributions to #ChildHealth. The Award is presented TODAY, during the opening ceremony of the JSA/WAO/APAPARI Joint Congress 2026: ◆Opening Ceremony◆ 📅🕐 October 16, 18:00–18:45 (JST) 📍 Room 1 (Main Hall, 1st Floor, Kyoto International Conference Center) 🔗📶 site2.convention.co.jp/jsa20… . #PAI_journal #APAPARI #PediatricAllergy #ResearchExcellence #Award2026 #AtopicDisease #Kyoto2026 #Probiotic #oralimmunotherapy #immunotherapy #Japan #retrospectivestudy #Dibutylphthalate #AD #semaphorinplexin #IL5 #ECHOCOCOAstudy

doi.org/10.1111/pai.70480 📌 Key message Recent advances in pediatric #asthma management focus on: ✅ Early control of airway inflammation ✅ Prevention of asthma attacks ✅ Steroid stewardship ✅ Biomarker-guided biologic use ✅ Long-term preservation of lung function Read this comprehensive review in #Pai_journal . #PediatricAsthma #AsthmaCare #Biologics #asthmamanagement #biomarkers #diseasemanagement

🏆 PAI–APAPARI Award 2026 We are delighted to celebrate the outstanding research recognized by this year's PAI–APAPARI Award. The award will be presented during the Opening Ceremony of the JSA/WAO/APAPARI Joint Congress 2026 in Kyoto, Japan 📅 Friday, October 16, 18:00–18:45 (JST) 📍 Venue: Room 1 (Main Hall, 1st Floor, Kyoto International Conference Center) 🔗 site2.convention.co.jp/jsa20… Congratulations to the authors of the three outstanding papers selected for this year's award: 🔹 Probiotic oral immunotherapy for egg and milk allergy induces sustained unresponsiveness 🛜 10.1111/pai.70222 🔹 Eleven-year trends in walnut-induced anaphylaxis in children in Japan: a multicenter retrospective study 🛜 10.1111/pai.70243 🔹 Dibutyl phthalate induces atopic dermatitis via semaphorin-plexin signaling and IL-5: ECHO-COCOA study 🛜 10.1111/pai.70224 These studies highlight the breadth and impact of current research in pediatric #allergy and #immunology, from #foodallergy and #anaphylaxis to environmental drivers of #atopicdisease. Congratulations to all #awardees, and thank you for advancing the care of children worldwide. 🌍✨ #PAI_journal #APAPARI #PediatricAllergy #AtopicDermatitis #ResearchExcellence #Kyoto2026 #Probiotic #oralimmunotherapy #immunotherapy #Japan #retrospectivestudy #Dibutylphthalate #AD #semaphorinplexin #IL5 #ECHOCOCOAstudy

❓ Could a simple blood biomarker help identify different allergic airway disease phenotypes? Researchers found that specific odd-chain fatty acids were altered in children with allergic #rhinitis and #asthma, suggesting the presence of a distinct #immunometabolic profile. The work highlights the growing role of #metabolomics in pediatric allergy research. Check this out 🔗 doi.org/10.1111/pai.70483 . #fattyacid #allergicrhinitis #Metabolomics #PAI_journal #immunometabolicprofile #oddchainfattyacid #biomarker #airwayphenotypes

Earlier allergen introduction is becoming more common. 🥜 Compared with the pandemic-born #CORALcohort, infants in the #FLORALcohort were significantly more likely to have introduced: 🥚 Egg 🥜 Peanut 🐟 Fish 🥛 Cow's milk by 6 months of age. These evolving feeding practices may have important implications for #immune tolerance and #allergy prevention. Take a look here 🔗 doi.org/10.1111/pai.70471 . #FoodAllergy #PAI_journal #birthcohort #earlyallergenintroduction #allergen #earlylifeexposures #microbiome #SARSCoV2pandemic #immunetolerance #allergyprevention

🩹 Persistent impetiginized lesions improved after #dupilumab treatment in children with #atopicdermatitis. A #clinicalletter to remind of the broad benefits that may accompany effective control of type 2 #inflammation. 🔗 doi.org/10.1111/pai.70478 #AD #type2inflammation #PAI_journal #refractoryimpetiginizedlesions

Does childhood eczema increase the risk of ADHD? 🧠 In this longitudinal #birthcohort, researchers found no significant association between early, late-onset, or persistent #AtopicDermatitis and #ADHD by 10–12 years of age. These findings suggest that the #timing and #persistence of childhood #eczema may not independently influence the risk of ADHD. 🔗 doi.org/10.1111/pai.70485 #AD #ADHD #PediatricAllergy #PAI_journal #atopicdisease #attentiondeficithyperactivitydisorder

World Mental Health Day 🧠💚 Living with allergic diseases can affect more than physical health. Conditions such as atopic dermatitis, food allergy, asthma, and allergic #rhinitis may also impact emotional well-being, #sleep, school performance, and quality of life. Today, we recognize the importance of caring for both mental and physical health, and of supporting children and families living with chronic allergic diseases. Because every child deserves to breathe, sleep, play, learn, and thrive. 💚 #WorldMentalHealthDay #MentalHealth #PediatricAllergy #AtopicDermatitis #FoodAllergy #Asthma #PAI_journal #AD #emotionalwellbeing #qualityoflife #QoL

Does eating a wider variety of foods in infancy influence eczema risk? In this nationwide Korean cohort of more than 267,000 children, lower #dietary diversity during the first year of life was associated with a higher #risk of #AtopicDermatitis. Eating the #rainbow early: Food diversity in infancy and the risk of atopic dermatitis in 267,935 Korean children 🔗 doi.org/10.1111/pai.70487 #AD #InfantNutrition #PAI_journal #Koreancohort #fooddiversity

When #MicrobialFunction changes, disease expression may change too. 🦠 Understanding the gut #microbiota in #A20 haploinsufficiency could open new avenues for precision medicine and targeted interventions. Take note of this 🔗 doi.org/10.1111/pai.70484 . #Microbiome #Functionalchanges #PAI_journal #gutmicrobiota #intestinalphenotype #A20haploinsufficiency