Acinetobacter baumannii, antibiotic resistance, small RNA, infectious diseases and much more...
IIT Roorkee, India
Joined August 2018
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Ranjana Pathania retweeted
Obesity may undermine #antibiotics in ways beyond drug resistance. Acetate restored immune function, sensitized A. baumannii to tobramycin & improved bacterial clearance. A #microbiota-derived metabolite shows promise as an antibiotic adjuvant. doi.org/10.1128/mbio.01630-2… #IITRoorkee
Ranjana Pathania retweeted
The next article in #RNAseries, features @pathanialab, IA Senior Fellow.
She studies how small non-coding RNAs help Acinetobacter baumannii adapt to stress and regulate processes such as metabolism and survival.
Our recent study on Acinetobacter baumannii, a WHO priority pathogen, explores metabolic resilience and uncovers synthetic lethal interactions that can be exploited for therapeutic interventions. | mBio journals.asm.org/doi/10.1128…
@AvikPathak2 @SnehlataSaini1 @India_Alliance
Calling for your paper for the upcoming collection - Antimicrobial resistance
I’m honored to be serving as the collection’s Guest Editor and eager to read your submission. Learn more about the collection and how to contribute: go.nature.com/4v7tdvN
@NaturePortfolio
#AMR
Thrilled to share, our team has broken the old dogma in #Acinetobacter research! The study reveals that antioxidant enzyme long annotated as Fe-SOD is, in fact, Mn- SOD. It also proves Mn- SOD is vital to withstand the host’s oxidative burst . 10.1016/j.jbc.2025.110549
United Against Superbugs! Teamwork triumphs! Grateful for the incredible collaboration that made Compound 3b a reality—together we’re pushing the boundaries in the fight against antibiotic resistance!
#IITRoorkee #UiT Tromsø @AnnetteBayer7
@HKS_Leiros
@drmangalb
@PerwezBakht
IIT Roorkee & UiT Tromsø researchers led by Prof. Ranjana Pathania develop Compound 3b, a β-lactamase inhibitor that restores Meropenem’s effectiveness against KPC-2 superbug Klebsiella pneumoniae. Published in J. Med. Chem.
#IITRoorkee #DrugDiscovery #AMR
Glad to share our recent study which presents a live attenuated hfq-deleted Acinetobacter baumannii vaccine which protects against systemic infection in-vivo. Check out the publication at doi.org/10.1016/j.vaccine.20… @iitroorkee
Plant-based compounds like thymol can boost antibiotic effectiveness by targeting persister cells! Our recent study shows that thymol reduces bacterial relapse, opening new avenues for using natural products to enhance existing treatments @ASMicrobiology
Thrilled to share our latest work! We reveal how Acinetobacter baumannii fine-tunes its Type VI secretion system through a manganese-dependent small RNA, unravelling new layers of bacterial pathogenesis! @India_Alliance @iitroorkee
Research at @iitroorkee offers insight into Acinetobacter baumannii, a top priority pathogen causing nosocomial infections that represses type VI secretion system through a manganese-dependent small RNA-mediated regulation.
@DrJitendraSingh @rajesh_gokhale
@India_Alliance @SMCC_NIScPR
Ranjana Pathania retweeted
Scientists at IIT Roorkee, led by Prof. Ranjana Pathania, have uncovered how the superbug Acinetobacter baumannii regulates its defense system. Their mBio (ASM) study identifies AbsR28, a small RNA controlling T6SS, offering new targets for tackling antibiotic resistance.
Looking forward to an interactive event with colleagues attending from across the globe! @sunishk @ViollierPat @India_Alliance
Our editorial board member @pathanialab will attend the Bacterial Morphogenesis, Survival and Virulence (BMSV) conference in Cape Town, South Africa (Feb 2-7) - giving a talk on #Acinetobacter sRNA-T6SS regulation ncbs.res.in/bmsv
Rinki and Timsy's recent work on cell wall inhibitors unveils the crucial role of L,D-transpeptidase A in mecillinam resistance #ACSInfectiousDiseases @rinkigpta @TBhando
pubs.acs.org/doi/10.1021/acs…
Mahak, Arsalan and Amit's work shows that Fosfomycin can be used against Acinetobacter baumannii in UTIs if combined with an efflux pump inhibitor....this study also made it to the cover page of ACS Infectious diseases pubs.acs.org/toc/aidcbc/10/5
One PDF position is available in the area of small RNA-mediated gene regulation in Acinetobacter baumannii physiology in my research group at IIT Roorkee. We are looking for highly motivated researcher to join us. Interested candidates may contact me. @iitroorkee #Job #hiring
Excited to share that our recent study, led by @MahakS23 ,@gauravamit4 and @Arsalan41000878, is gracing the cover of ACS Infectious diseases! Our work discovers a novel EPI that potentiates Fosfomycin against Acinetobacter baumannii. @ACS4Authors @iitroorkee #MyACSCover
Thrilled to share that our latest designed cover art image and review article, "Chemical genetic approaches for the discovery of bacterial cell wall inhibitors" just landed on the pages of @rsc_medchem Big ups to the squad @rinkigpta @drmangalb @iitroorkee pubs.rsc.org/en/journals/jou…
Delighted to be featured as Reviewer of the Month for Communications Biology for August 2023.
nature.com/commsbio/referees…
Mahak and Amit's work on IITR00693 which sensitizes inherently resistant Staph and other
Gram positives to polymyxin....@ACS4Authors#MyACSCover
@iitroorkee researchers led by Prof Ranjana Pathania, discover New Antibacterial Molecule Against Superbugs, the molecule has shown potent antibacterial activity against a wide range of Gram-positive and Gram-negative bacteria
@drbalramaiims @pathanialab @MahakS23 @serbonline
So pleased and honoured to be a part of the NASI family,kudos to my brilliant team mates (present and past)!
Heartiest congratulations to Prof. Ranjana Pathania for being elected as a Fellow of the National Academy of Sciences, India #NASI. She is an @iitroorkee Professor at the Department of Biosciences and Bioengineering.
Prof. Ranjana Pathania is currently a DBT/Wellcome-
