@promiselcooper
Joined September 2016
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  • Following61
  • Followers123
From a proud mom, congrats to Declan @DeclanLMCooper and all the team for this monumental, beautifully presented work in @nature, doi.org/10.1038/s41586-023-0…. Endless love to you and all the trees
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julie cooper retweeted
Joe Nassour@NassourJoe20 Nov 2023
Our latest review 'Telomeres as hotspots for innate immunity and inflammation' is now live @repair_dna! Here, we describe how dysfunctional telomeres activate innate immune pathways and fuel inflammaging. Check it out @Sprzetocka @KarlsederLab doi.org/10.1016/j.dnarep.202…
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Check out this work driven by the awesome Rishi Nageshan. Entangled telomeres? Expose them to the cytoplasm asap to resolve those entanglements…
bioRxiv@biorxivpreprint26 Feb 2023
Fate of telomere entanglements is dictated by the timing of anaphase midregion nuclear envelope breakdown biorxiv.org/cgi/content/shor… #bioRxiv
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Repeated strand invasion and extensive branch migration are hallmarks of meiotic recombination biorxiv.org/content/10.1101/… In which @jasvinderahuja did tetrad analysis on steroids (the analysis, not Jasvinder) and learned some remarkable things about recombination mechanisms. Enjoy.

Repeated strand invasion and extensive branch migration are hallmarks of meiotic recombination

Currently favored models for meiotic recombination posit that both noncrossover and crossover recombination are initiated by DNA double strand breaks but form by different mechanisms, noncrossovers...

biorxiv.org
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Our collaborative paper on #behaviour of #zebrafish with short #telomeres is out. We show that #tert mutants are more #pessimistic in response to ambiguous stimuli. We are now looking for the underlying causes of this behaviour. @ircaninstitute @CNRS_DR20 royalsocietypublishing.org/d…

Short telomeres drive pessimistic judgement bias in zebrafish

Abstract. The role of telomerase reverse transcriptase has been widely investigated in the contexts of ageing and age-related diseases. Interestingly, decr

royalsocietypublishing.org
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Check out our review on telomerase, cancer and stem cells - live at Nature Reviews Molecular Cell Biology @NatRevMCB. It highlights recent breakthroughs in the field and co-authored with my Stanford MSTP student Caitlin Roake. go.nature.com/39zddaU #CancerResearch #Telomeres
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julie cooper retweeted
The Rog Lab@TheRogLab18 Mar 2021
Exciting week for the Rog Lab - the first two papers form the lab have been published in @CurrentBiology and @PLOSGenetics journals.plos.org/plosgeneti… sciencedirect.com/science/ar…

Synaptonemal Complex dimerization regulates chromosome alignment and crossover patterning in meiosis

Author summary Meiosis is a specialized cell division cycle during which maternal and paternal chromosomes are brought together, exchange information and separate into new cells that become gametes,...

journals.plos.org
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Why centromeres need telomeres... Centromeres are dismantled by foundational meiotic proteins Spo11 and Rec8 disq.us/t/3va2a42 Kudos to Haitong Hou, @efty_ky, Rahul Thadani, @KlutsteinlbCARL and Joe Chapman with whom it's been a pleasure and privilege to work!
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