Computing power consumer, PhD
Joined May 2017
- Tweets267
- Following873
- Followers135
- Likes2.3K
Ruitao Jin 金瑞涛 retweeted
So great to see our structure of chlorophyll synthase on bioRxiv! Thanks to amazing collaboration with Anna Wysocka, Felix @BurrowsMorey, Andy @HitchcockLab and Roman Sobotka, and everyone else involved!
@UniOsnabrueck @AlgatechTrebon @sheffielduni
#cryoEM #photosynthesis #cyano
Ruitao Jin 金瑞涛 retweeted
I am delighted to share our characterisation of natural antagonism of TLR7/8 in Nature Immunology. We propose a model where 2’O-Methyl RNA fragments keep TLR7/8 in check, preventing autoimmunity. > nature.com/articles/s41590-0…
Ruitao Jin 金瑞涛 retweeted
Even eagles live in fear - just by chance I looked up and saw this eagle being pursued by a magpie
Ruitao Jin 金瑞涛 retweeted
Cryo-EM of fertilisation complex Pfs230-Pfs48/45 from malaria parasites! 💕
🦟 Transgenic parasites without Pfs230 D13D14 do not transmit
🦙 💉Nanobodies + mRNA induced antibodies reduce transmission
New in @ScienceMagazine
science.org/doi/10.1126/scie…
#ScienceResearch #Malaria
Ruitao Jin 金瑞涛 retweeted
AlphaFold2 captures conformational transitions in the voltage-gated channel superfamily biorxiv.org/content/10.1101/… #biorxiv_biophys
Ruitao Jin 金瑞涛 retweeted
Stabilized PvRBP2b variants - fun collab + Sarel Fleishman
🔥Increased yields & thermal stability
✌️Maintains human mAb recognition
🩸Sensitivity as sero-diagnostic for P. vivax
💕 Editors Pick
👨🏻🔬First paper PhD student Jaison
Please read & repost!
jbc.org/article/S0021-9258%2…
Ruitao Jin 金瑞涛 retweeted
Image shows accessibility via the fenestrations of Nav1.5 to drug compounds & lipid tails. @whoiselainetao & @CorryLab offer insights for improving therapeutic development for conditions like chronic #pain, #epilepsy, and cardiac #arrhythmias. hubs.la/Q031H1yW0
#IonChannels
Ruitao Jin 金瑞涛 retweeted
Proud of our latest work w/ the Zhang lab showing from structure & simulation how XPR1, the only known human Pi exporter, is regulated by InsP8 & KIDINS220 + Pi selection/permeation by a channel-like knock-kiss-kick mechanism
💻 @ciara__wallis @Riottowow
tiny.cc/xpr1
Ruitao Jin 金瑞涛 retweeted
NCAP: Noncanonical Amino Acid Parameterization Software for CHARMM Potentials #MolecularDynamics #CHARMM
pubs.acs.org/doi/10.1021/acs…
#JCIM Vol64 Issue24 #compchem
Ruitao Jin 金瑞涛 retweeted
Excited to start the year with this lovely paper with @whoiselainetao showing that drugs that inhibit sodium channels bind in a range of sites within the pore cavity rather having a single distinct pose.
@JGenPhysiol @scienceANU @NCInews
Tao and Corry @CorryLab @ANU_RSB_BSB investigate the binding of sodium channel inhibitors to the Naᵥ1.5 pore using simulations, revealing promiscuous, polyspecific binding at the fenestrations and central cavity. hubs.la/Q031spy70
Ruitao Jin 金瑞涛 retweeted
Nature research paper: Synthetic GPCRs for programmable sensing and control of cell behaviour go.nature.com/4g0j4cg
Ruitao Jin 金瑞涛 retweeted
Another great source of scientific art for figures by NIH! bioart.niaid.nih.gov/bioart/… 🙏🏼✨
Ruitao Jin 金瑞涛 retweeted
Is this the solution to your problems? 🤔
Wombats have their own challenges. But if you became a wombat you'd never need to decide what to make for dinner again.
Just something to consider this #WombatWednesday.
📷 | Inspired by "Become a crab" meme, creator unknown
ALT Picture of a wombat. Text around the wombat reads "Overwhelmed by adult responsibilities? Sick of folding laundry? Don't know what to do? Become a wombat! - no bills - food is all around - never worry - can use bum for protection - can run really fast - never need manicures - everything is a scratching post"
Ruitao Jin 金瑞涛 retweeted
And congratulations to our second-place winner, Alejandro Dagnino for his image "Lasagna"🥈 View the alt-text for the caption!
ALT Similar to lasagna, cell membranes are layered structures. Just as the pasta layers in lasagna provide essential support for the meat, cheese, and sauce, the cell membrane offers structural support crucial for the cell's survival. Without a membrane, a cell would resemble a lasagna without pasta, a mess.
Ruitao Jin 金瑞涛 retweeted
De novo protein design is great, but nature has millions of proteins- why not repurpose them?
Introducing Raygun, a new approach to protein design. It allows you to miniaturize, magnify or modify any protein. We synthesized miniaturized variants of eGFP and mCherry! 1/
Ruitao Jin 金瑞涛 retweeted
Excited & proud of the fantastic @yiechanglin for her wonderful exit seminar & submitting her PhD thesis 🎆🎉
YC has been an integral part of our lab and @RSB, & we can't wait to see all the amazing things she will achieve as #DrLin 👩🔬
#PhDone #Doctor #ProudSupervisor #LabStar
Ruitao Jin 金瑞涛 retweeted
Yixiao Zhang and I wrote a research briefing for @Nature on our recently published work with the @CorryLab. Lipids act as structural components of the pore of an ion-channel family. nature.com/articles/d41586-0…