Radiation Oncologist ASST Papa Giovanni XXIII, Neurooncology, Hematological Malignancies, Radiosurgery, Total Body Irradiation
Bergamo, Lombardy
Joined October 2021
- Tweets248
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Roberta Muni retweeted
Happy to share our last article on SRS for resected BM. Our resuls indicate that both 3 × 9 Gy and 5 × 6 Gy are effective SRS treatment modalities associated with
high local control and low risk of symptomatic radionecrosis.
link.springer.com/10.1007/s1…
@SapienzaRoma
Roberta Muni retweeted
🧠 New paper in Neuro-Oncology
📄 Epigenetic evolution of IDH-wildtype glioblastomas
MGMT promoter status is stable in ~93% of cases from diagnosis to recurrence.
➡️ MGMT at diagnosis usually remains clinically valid at recurrence.
academic.oup.com/neuro-oncol…
#Glioblastoma #MGMT
Roberta Muni retweeted
Must read: ESTRO-ISRS clinical practice recommendations for re-irradiation of spinal metastases with Stereotactic Body Radiotherapy: Delphi consensus supported by a systematic review and meta-analysis
sciencedirect.com/science/ar…
Roberta Muni retweeted
RT with 5 × 5 Gy for Personalized Treatment of Malignant Epidural Compression: Long-Term Results of the PRE-MODE Trial
Congrats and thanks to Prof Rades for counting on me☺️
mdpi.com/2075-4426/15/12/577
Roberta Muni retweeted
Fantastic talk by Martin van de Bent on the long-term results of @EORTC CATNON trial at @EANOassociation #2025Prague. soon on @TheLancetOncol
- Adjuv TMZ (no concurrent) provides meaningful OS results.
- With a m OS of about 12 y, 45% G3 IDH-mut astro pts are still alive.
Roberta Muni retweeted
This study found that #nilotinib was safe but had limited activity in biomarker-selected recurrent #HGGs. A few patients had exceptional responses, underscoring the need to better understand glioma genomic aberrations & their influence on targeted therapy
bit.ly/4qlLKSK
Roberta Muni retweeted
The evidence-based safety statements developed during this @myESMO @ESTRO_RT project, provide practical guidance on combining RT with targeted cancer therapies and immunotherapy.
💫🌟🚨 Ann Oncol ESMO–ESTRO Consensus
Safety of combining RT with systemic therapies
Authors: @GPentheroudaki @umbertoricardi @gminniti2012 @DrAngelaLamarca
@OncoAlert
🔑 Key messages:
🔵 ICI + RT: Feasible in selected scenarios, but monitor for ↑risk pneumonitis & late toxicities
🟢 VEGF(R)-inhibitors + RT: Careful with bleeding & wound healing complications
🟡 TKIs + RT: Drug–RT interactions may exacerbate toxicity; dose/timing adjustments essential
🟣 Evidence gaps remain → strong call for multidisciplinary decision-making
🔴 Practical guidance for safe integration in clinical trials & practice
👥
@myESMO @ESTRO_org @ASCO
#RadOnc #Immunotherapy #TargetedTherapy #OncoTwitter #ESMO
annalsofoncology.org/article…
Roberta Muni retweeted
Congrats to the @ISRSy guideline committee on this fantastic guideline on the management of cavernous sinus hemangioma with SRS @IJROBP. Radiation, be it SRS or fractionated radiotherapy, is the standard of care achieving sustained long term local control.
pubmed.ncbi.nlm.nih.gov/4081…
Roberta Muni retweeted
New in #practicalRO: Postoperative Stereotactic Radiosurgery for Resected Brain Metastases: Targeting of the Surgical Tract. #radonc tinyurl.com/prorivers
Roberta Muni retweeted
This is a big unanswered question.
Do you contour the surgical tract? I don't do and I have seen very few progression (<3%)
@SapienzaRoma
New in #practicalRO: Postoperative Stereotactic Radiosurgery for Resected Brain Metastases: Targeting of the Surgical Tract. #radonc tinyurl.com/prorivers
Roberta Muni retweeted
So proud to share mid-term results of our POPART trial on prostate bed SBRT — core of my thesis and a project I deeply believe in ✨
Alongside #SCIMITAR & #SHORTER, another step towards the 5fx revolution! 💥
Forever🙏🏼@StAr_MCM74
50days free access⬇️
authors.elsevier.com/c/1lYbQ…
Roberta Muni retweeted
Volumetric assessment should be considered for most brain tumors: Prognostic value of 1D, 2D, and volumetric tumor size increases in recurrent WHO grade 2-3 meningiomas: Radiological post-hoc analysis of the EORTC-BTG-1320 trial academic.oup.com/noa/article…
@EORTC
@EANOassociation
Roberta Muni retweeted
must read.. neurocognitive impact of brain treatments are one of the most important topic in our field. Putting many efforts on that with great research groups at @SapienzaRoma @NeuromedIRCCS @UPMC Roma FBF
Saviola et al. @FrancescaSavio9 @SSarubbo showed that presurgical dynamic properties of executive networks, especially fronto-parietal network, can predict short-term attention deficits and recovery after glioma resection. #JNO
Read more:link.springer.com/article/10…
Roberta Muni retweeted
New in #practicalRO: Radiation Therapy for WHO Grade 4 Adult-Type Diffuse Glioma: An ASTRO Clinical Practice Guideline. #radonc tinyurl.com/probovi
Roberta Muni retweeted
Shifting away from elective nodal irradiation in HNSCC: What do we know and where are we heading? Kudos to Julien Biau for leading this. @PBlanchardMD @sueyom @joncaci @RO_GreenJournal sciencedirect.com/science/ar…
Implementation and dissemination in Radiation Oncology. Do you agree with us? sciencedirect.com/science/ar…
Roberta Muni retweeted
Another dogma is disappearing: SRS is effective for SCLC BM.
Stereotactic Radiosurgery in Patients With Small Cell Lung Cancer and 1-10 Brain Metastases: A Multi-Institutional, Phase II, Prospective Clinical Trial | Journal of Clinical Oncology ascopubs.org/doi/10.1200/JCO…
Roberta Muni retweeted
Antiseizure medications, surgery, CHT, and RT contribute to controlling seizures in a multidisciplinary approach
Tumor‐related epilepsy in glioma: A multidisciplinary overview - Michelucci - Epilepsia - Wiley Online Library onlinelibrary.wiley.com/doi/…
@SapienzaRoma
Roberta Muni retweeted
Happy to see these data presented at ASCO2025 now in JCO. I am not surprised. We use this approach in most of our patients who are on systemic therapy. I don't see the reason to target 1200 ml of normal brain with WBRT vs small cc cumulative tumor with SRS
Stereotactic radiation versus hippocampal avoidance whole brain radiation in patients with 5-20 brain metastases: A multicenter, phase 3 randomized trial. | Journal of Clinical Oncology ascopubs.org/doi/10.1200/JCO…
Roberta Muni retweeted
must read..
Multi-Institutional Atlas of Brain Metastases Informs Spatial Modeling for Precision Imaging and Personalized Therapy, published in Nature Communications.
👉 Read it before your patients: bit.ly/45Kmca1
@NatureComms
