The Somatic Cell Genome Editing Consortium is funded by the @NIH_CommonFund. Retweets ≠ endorsements. Visit the SCGE Platform https://xitter.cf/t.co/HSVaRDh4B4
Joined September 2019
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Somatic Cell Genome Editing (SCGE) Outreach retweeted
Hot off the press! 📢 Our Q3 2026 Gene, Cell and RNA Therapy Landscape Report, developed with Citeline, is here.
Explore seven new approvals, an expanding clinical pipeline and the latest advancements shaping the field.
Read more: bit.ly/4ufliLp
#ASGCT #CGT
We're back with another SCGE Spotlight! This month, we've got:
- 2 recent publications
- Links to our "Meet the Expert" webinar series recordings
- Upcoming SCGE researcher presentations at ASGCT Breakthroughs
linkedin.com/pulse/scge-spot…
Somatic Cell Genome Editing (SCGE) Outreach retweeted
On September 29th, the SCGE hosted a public workshop titled “Rethinking Clinical Delivery, Regulation, and Payment Models for Individualized Platform-Based Genome Editing Therapies”.
The recording for this workshop is available now at: youtube.com/watch?v=5FnuGKb1…
On September 29th, the SCGE hosted a public workshop titled “Rethinking Clinical Delivery, Regulation, and Payment Models for Individualized Platform-Based Genome Editing Therapies”.
The recording for this workshop is available now at: youtube.com/watch?v=5FnuGKb1…
Somatic Cell Genome Editing (SCGE) Outreach retweeted
New piece in @CGT_Insights on scaling individualized CRISPR therapeutics:
The technical challenge: conventional biomanufacturing optimizes for volume, but individualized gene therapy requires treating each patient as their own 'batch.' @somaticediting
10.18609/cgti.2026.087
ALT Challenges in biomanufacturing individualized CRISPR therapeutics
Here, SCGE researchers demonstrate that selective organ targeting (SORT) lipid nanoparticles (LNPs) encapsulating optimized Cas9 cargo facilitate efficient, local delivery to skeletal muscle.
cell.com/molecular-therapy-f…
Here, a team including SCGE researchers have developed a cost-effective mass-production method for manufacturing vascularized kidney organoids, which has improved production efficiency by more than 50 times compared to conventional culture systems.
pmc.ncbi.nlm.nih.gov/article…
Somatic Cell Genome Editing (SCGE) Outreach retweeted
As AI and biotech converge and reach deeper into our lives, critical questions around the technology's purpose and trajectory emerge. Join us for "Engineering Health for the Common Good" @UWMadison!️ FREE, open to the public: graingerinstitute.engr.wisc.…
#Bioethics #CRISPR #AI
ALT https://graingerinstitute.engr.wisc.edu/engineering-health-symposium/
We had a great few days at our SCGE workshop and consortium meeting. Thank you to everyone who participated and attended!
Here, SCGE researchers discuss their idea for the use of a customizable prime editing platform in an "umbrella-of-umbrellas" clinical trial including subjects with any of seven urea cycle disorders. #PublicationFriday
sciencedirect.com/science/ar…
Our steering committee update from Dr. Rebecca Ahrens-Nicklas highlighted some exciting wins from our consortium researchers.
SCGE Workshop Final Panel
Panelists: PJ Brooks, Anna Kwilas, Rebecca Ahrens-Nicklas, Janet Woodcock, Jack Tyndall, Winston Yan, Jayson Slotnik
SCGE Workshop Session 4
Moderator: Shyam Patel
Speakers: Winston Yan, David Tischler, Jayson Slotnik
Panelists: Shyam Patel, Winston Yan, David Tischler, Jayson Slotnik
SCGE Workshop Session 3
Moderator: Deanna Portero
Speakers: Jessica Galens, Jack Tyndall, Mitchell Zack, Caroline Larson
Panelists: Deanna Portero, Jessica Galens, Jack Tyndall, Mitchell Zack, Caroline Larson
SCGE Workshop Session 2
Moderator: Brian Stultz
Speakers: Jacob Bitterman, Aimee Magnarelli, Dan O'Connor
Panelists: Brian Stultz, Jacob Bitterman, Aimee Magnarelli, Dan O'Connor
Findings from SCGE researchers suggest that liver base editing may benefit individuals with ZSD and provides a foundation for developing precision gene correction treatments that address the root cause of a wide range of peroxisomal disorders.
nature.com/articles/s41551-0…
