PhD in Cancer Biology / NRSA Ruth L Kirschstein Predoctoral Fellow / Jeff Rathmell lab / RIT Alum / Vanderbilt Assistant Rowing Coach
Joined July 2014
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KayLee Steiner, PhD retweeted
#ScienceSaturday
❓ Could targeting T cell metabolism be the next big thing in boosting cancer immunotherapy?
➡️ New research shows tweaking how T cells use fat can change their survival and power.
➡️ In this study, @steinerkaylee, @JeffRathmell et. al found that a gene called MECR helps T cells get the energy they need to fight disease. Without MECR, T cells struggle to survive and do their job.
🌟 By understanding these metabolic pathways, we might find new ways to make cancer-fighting T cells even stronger! Exciting possibilities ahead! #Immunology #Immunotherapy #CancerResearch
🔗 Here’s a link to the full study- academic.oup.com/jimmunol/ad…
Excited to officially share my thesis work on the @JeffRathmell lab has been published in the Journal of Immunology! Thank you to all our collaborators who helped along the way.
academic.oup.com/jimmunol/ad…
It is great when science can have direct impacts to patients and make connections and collaborate. I hope we can all find ways to relate our science to patients and improve outcomes more!
Beyond MEPAN: the role of MECR in immune metabolism. Thank you to Dr. KayLee Steiner for illuminating more about the importance of MECR and mtFAS to human health. @steinerkaylee
mepan.org/post/mecr-role-in-…
ALT A Human T-Cell
Excited to share I successfully defended my PhD in Cancer Biology from Vanderbilt University in the laboratory of @JeffRathmell Thank you to all my collaborators, friends, and family for the endless support!
#PhinisheD #immunometabolism
KayLee Steiner, PhD retweeted
Big congratulations to @steinerkaylee for her PhD defense! As always, KayLee goes big--tackling a poorly understood metabolic pathway in T cells (mtFAS) and with a huge bottle to celebrate after.
KayLee Steiner, PhD retweeted
Please join me in congratulating Hudson Lab Alumna, Dr. KayLee Steiner @steinerkaylee on successfully defending her PhD dissertation today! Well done Dr. Steiner and Dr. @JeffRathmell
KayLee Steiner, PhD retweeted
Check out the latest drop from the @JeffRathmell lab by the extraordinary @DarrenHeintzman! This project was intellectually stimulating for all in the lab and fun to be a part of. See how temperature impacts T cell metabolism! science.org/doi/10.1126/scii…
🌡️🔥
As co-executive chair for the Cancer Biology Student Association, I organized our Cancer Biology retreat where we hosted @NCIDirector Dr. Kim Rathmell. Thank you to all our chairs to make this retreat a success and silent auction to benefit @GildasClubMidTN
Second and probably last SIS ✅ I was selected to give an oral presentation as an AAI young investigator out of over 200 abstracts!!
Excited to share that @DrARPatterson paper is out! I did my rotation with Andrew in @JeffRathmell lab and happy to have helped him with his experiments and projects.
science.org/doi/10.1126/scii…
KayLee Steiner, PhD retweeted
Great job by @steinerkaylee of my group and @VUMC_VCI as an @ImmunologyAAI Young Investigator awardee to present her work at the #SIS2024 Southeast Immunology Symposium at @UABImmunology
KayLee Steiner, PhD retweeted
Mitochondrial Fatty Acid Synthesis and Mecr Regulate CD4+ T Cell Function and Oxidative Metabolism biorxiv.org/cgi/content/shor… #biorxiv_immuno
My first author paper from my thesis work has been uploaded to BioRxiv! We identified Mecr as important for T cell fitness in in vivo CRISPR screens. I have further worked with Mecr and am the first to show it regulates T cell function and metabolism.
biorxiv.org/content/10.1101/…
Excited to share that I have received my NoA and my F31 has officially been FUNDED! Thanks to everyone in the lab for their help especially @JeffRathmell
KayLee Steiner, PhD retweeted
My former @RITscience UG scholar colleague and current PhD student at Vanderbilt University, KayLee Steiner’s work. #RIT
KayLee Steiner, PhD retweeted
It's out! @JackieEBader led our new @TheMarkFdn Endeavor team study showing obesity promotes PD-1 on macrophages to suppress anti-tumor immunity but sensitize to checkpoint therapy--a new mechanism of the cancer "obesity paradox" @VUMC_VCI @VUMC_Cancer
nature.com/articles/s41586-0…
So happy to have helped Jackie with experiments for her paper now published in NATURE! 👩🏼🔬🎉
Cannot express how excited I am that our paper is finally out in real life!
Macrophages contribute to the obesity paradox. We found PD-1 acts directly on macrophages to alter metabolism and suppress their anti-tumor function in obesity associated cancers.
nature.com/articles/s41586-0…
Excited to share my first co-authorship of grad school in @JeffRathmell lab with hard work of first-author @melissa_m_wolf in JCI! jci.org/articles/view/173934
KayLee Steiner, PhD retweeted
MITOchats are back this Thursday! We are opening Season 5 with three short talks by KayLee Steiner @steinerkaylee @JeffRathmell, Juan Landoni @jclandoni, and Mariella Quisepe-Carbajal @mqcarba. Zoom link now available on mitotalks.org
The MITOscience of tomorrow, today.
