Charles Leduc, MD (@thoracicpath) profile picture

Thoracic pathologist, University of Montreal Health Center

Joined October 2019
Photo by Charles Leduc, MD (@thoracicpath)Photo by Charles Leduc, MD (@thoracicpath)Photo by Charles Leduc, MD (@thoracicpath)Photo by Charles Leduc, MD (@thoracicpath)Photo by Charles Leduc, MD (@thoracicpath)Photo by Charles Leduc, MD (@thoracicpath)Photo by Charles Leduc, MD (@thoracicpath)Photo by Charles Leduc, MD (@thoracicpath)Photo by Charles Leduc, MD (@thoracicpath)Photo by Charles Leduc, MD (@thoracicpath)
The history of Congo red‐stained amyloid is an example of how an erroneous belief can become widely established even when it is contradicted by simple experience: "Congo red‐stained amyloid just shows “apple‐green birefringence" (PMID: 31515863) ncbi.nlm.nih.gov/pmc/article…
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Hi all! So we all know about constrictive bronchiolitis, but can it happen in large airways? Below is post-SBRT obliterative bronchitis of LLL with secondary necrotizing granulomatous consolidation - awaiting stains but betting on NTM. A sort of (non) middle lobe syndrome!
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Charles Leduc, MD retweeted
Do you recognize these seed-derived storage cells (images courtesy of @oreoimc)? See the latest publication on these cells and the lesions they produce co-authored by me, @Histopatolomon. and @navale_pooja at rdcu.be/cz4ZC. A Twitter inspired collaboration.
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Bag of worms. Hydrophilic polymer embolisation with secondary thrombosis. This is a thrombectomy specimen from the right femoral artery in a patient undergoing peripheral vascular surgery. The guidewires are coated in this material that can occasionally embolize. Yikes!
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Explants from woman in her mid 40s. Clinical history on req: pulmonary hypertension. IHC is CD1a. Unifying diagnosis?
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Thanks to all who engaged! Although uncommon, chronic LCH can lead to severe secondary pulmonary HTN which is what we see here. A spectrum of arterial lesions, including plexiform, dilatation, and medial hypertrophy. Wishing the patient a new lease on life with new lungs!
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Charles Leduc, MD retweeted
#Pulmpath #Thoracicpath #Pathbugs Excited to share unusual case ,Male 60s ,3.8 cm lung mass ,Bx sent as suspected malignancy ,look at the first set ,try to make the Dx ,then go to second set
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Charles Leduc, MD retweeted
We have lost a giant of #Pathology and #LungPath #PulmonaryPath. Dr. Sam Yousem, an admired colleague and friend died yesterday. He will be missed and remembered.
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- Lung development stage? Canalicular Lung (16-25 WGA) - Is it perinatal pneumonia? Aspirated amniotic exudate - What are placental findings? Acute Necrotizing Chorioamnionitis with Funisitis #placenta #perinatal (😬 I forgot @basophil_brett) 🥇@leon_metlay 🥈@grenierkarlMD
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For #PathResident Lung section 20WGA - premature labor, APGAR 1-1-1, no resuscitation: - Lung development stage? - Is it perinatal pneumonia? - What are placental findings? #PediPath @grenierkarlMD
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Usual Interstitial Pneumonia shows peripheral, lower predominant fibrosis in the #grosspath by @_Romo_Navarro Microscopically you can appreciate patchy fibrosis, fibroblastic foci & honeycomb #pulmpath #explantsRawesome #transplantpath #ILD
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True Thymic Hyperplasia in a 30 yo. Enlargement of normal thymus. Thymic cortices & medullae are well defined. Interstitial connective tissue is delicate with fat cells #pulmpath
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Young woman, endo tracheal lesion. What's your vote?
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The pictures in the previous tweet are most suggestive of :
6%Carcinoid tumour
8%AVM (arteriovenous malf)
80%Glomus tumour
7%Hemangioma
213 votes • Final results
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A huge thank you to all who engaged! As most of you surmised - this is a glomus tumor. As @RessChimes stated "round round, same same!" Those features + intimate relationship with vessel walls + smooth muscle markers = GT! Unusual in the trachea!
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Charles Leduc, MD retweeted
#PediPath #pulmpath 4 YO. Differential diagnosis? IHC you would suggest? #pathboards – at Pittsburgh, PA
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This material was removed from a bronchus. Can you answer this in one word? This finding is nearly always seen in patients with ....? #pathology #pulmpath
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