
@BrighamAnes ICU/Cardiac 🫀🫁 Fellow | @EmoryAnesthesia @RWJMS & 〽️ Wolverine | 🇰🇷 🇺🇸 roots | Resuscitation, MCS, AI/ML, and 🏃🏻
Boston, MA
Joined April 2010
- Tweets5K
- Following1.2K
- Followers2.4K
- Likes43.5K
Kitae (Tye) Chang retweeted
Replying to @tyechang
#ECMO in adults with congenital heart disease? Despite high mortality can be lifesaving when used judiciously!
🫀because of complex anatomy, prior interventions, unique physiologic adaptations, ACHD patients often require highly individualized management strategies + should ideally be managed in specialized centers
🗝️ key challenges, complicating cannulation & perfusion goals/management, include: altered vascular access, residual shunts, circulatory configurations like Fontan physiology or systemic right ventricles after atrial switch, and cyanotic heart disease
🖇️ bit.ly/4narwIT
Kitae (Tye) Chang retweeted
Hospitals Acquired By Private Equity Firms: Increased Postoperative Mortality For Common Inpatient Surgeries
@DiazAdrian10 @jdimick1 @Health_Affairs @UMichCHOP
healthaffairs.org/doi/abs/10…
Kitae (Tye) Chang retweeted
Our #Lp(a) JAMA Insights article is out!
ja.ma/3GnbYlc
Dr Florian Kronenberg and I summarize the latest on Lp(a) testing and management
@KronenbergLab
@atherosociety
@society_eas
@fhpatienteurope
High lipoprotein(a) levels, defined as 50 mg/dL or greater, are associated with increased rates of atherosclerotic cardiovascular disease events and all-cause mortality. This JAMA Insights discusses lipoprotein(a).
ja.ma/3GnbYlc
Kitae (Tye) Chang retweeted
Remember after you finish a race, comparison is the thief of joy. Some days you have it more than others. Your imperfect result is someone else’s dream time. And vice versa. That’s why racing is cool. You never know what can happen until you line up.
Kitae (Tye) Chang retweeted
Excited for this opportunity!
Congrats to our new Anesthesia & Analgesia Editorial Fellows: Drs. Emara, Gioscia-Ryan, Naylor, Tochie Noutakdie, and Rangasamy! #Anesthesiology #MedicalFellowship @IARS_Journals @openanesthesia More: ow.ly/X9b350Vz5lj
Kitae (Tye) Chang retweeted
Machine Learning for In-hospital Mortality Prediction in Critically Ill Patients With Acute Heart Failure: A Retrospective Analysis Based on the MIMIC-IV Database. #AI #machinelearning
jcvaonline.com/article/S1053…
Kitae (Tye) Chang retweeted
Privileged to contribute to @ISHBP article on "Harnessing demographic diversity in hypertension research and trials" ish-world.com/documents/ISH%…
Many ongoing efforts incl. @ourhealthstudy @nih_nhlbi MOSAAIC @AllofUsResearch @mchonig's @AHAScience Pressure Check study @MGHHeartHealth
Read the latest issue of Hypertension News - out today!
In this issue:
✅ Patient education
✅ Renal denervation
✅ Childhood hypertension
✅ New outcome studies in BP lowering
✅ The need for diversity in hypertension research
✅ And more
Read today: ish-world.com/ish-hypertensi…
Kitae (Tye) Chang retweeted
A common error in the ICU/ED we see: intubating patients on BIPAP after 4 hours (or even less!) that look comfortable JUST because their blood gas isn't improving.
Retweet if you have seen this practice yourself!
Check out my recorded discussion with @paulieac quoted below where we talk about this and MANY more NIV pearls (Paul is a NIV guru btw)
Instead:
1) Check to make sure a good mask seal --> if poor seal, your NIV isn't being delivered to pt.
2) Check your minute ventilation. Aim for ~0.1L/kg . So for an average person somewhere around 6-7LPM minute ventilation
3) Ensure appropriate indication (CHF/COPD over pneumonia)
4) Check your settings. For CHF, mean airway pressure more important (increase PEEP). For COPD, driving pressure more important (increase IPAP).
5) Make sure you are thinking about pulmonary toilet (e.g. breaks to cough, cough assist etc.)
Our discussion on NIV with @paulieac is starting at 11am EST March 27th. That's today in 30 minutes! Come hang out for 30-60min as we discuss NIV pearls and pitfalls.
Reply to this post with any specific questions you want us to discuss
teapaw.org/i/spaces/1LyGBWYByPnJN
Kitae (Tye) Chang retweeted
New from #ACC25: Dr. Nuccia Morici & colleagues report the results of ALTSHOCK-2, finding that early implantation of IABP does *not* reduce 60-day mortality in #heartfailure-related cardiogenic shock
#JACC 🧵 (1/4)
Kitae (Tye) Chang retweeted
🔥 Prothrombin Complex Concentrate vs Frozen Plasma for Coagulopathic Bleeding in Cardiac Surgery: The FARES-II Multicenter Randomized Clinical Trial | Bleeding and Transfusion | @JAMA | @JAMANetwork | #ACC25 🫀 jamanetwork.com/journals/jam…
Kitae (Tye) Chang retweeted
#Delirium is not just altered behaviour.
It is a manifestation of acute encephalopathy - measurable with EEG changes & altered biomarkers.
Kitae (Tye) Chang retweeted
Hyperoxia (elevated PaO₂) in VA-ECMO patients is linked to increased mortality, but this association may reflect poor native cardiac function rather than causation. #VAECMO jcvaonline.com/article/S1053…
Kitae (Tye) Chang retweeted
How do you measure cardiac output in your practice? This paper tackles what we need to know - Fick, thermodilution, pressure waveform analysis, pulse contour analysis, aortic Doppler, bioimpedance, and echocardiography. 🎩 tip to the authors.
eddyjoemd.com/foamed
Kitae (Tye) Chang retweeted
Do the IV fluids we provide to our critically ill patients trash the glycocalyx? This systematic review tackles this issue as we always try to balance benefit and harm. Another example where less could be more. 🎩 tip to the authors!
eddyjoemd.com/foamed/
Kitae (Tye) Chang retweeted
My most important rule for life: Don’t complain about anything. If it’s within your control, go and do something about it. If it’s not, you’re just wasting energy thinking about it. Complaining gives too much power to the thing. Take back that power.
Kitae (Tye) Chang retweeted
Measles-associated ARDS was not in my bingo card but if you need a refresher...
Kitae (Tye) Chang retweeted
The 2025 ACS guideline synthesizes new evidence since the 2013 STEMI and 2014 NSTEMI guidelines and the 2015 focused update on primary PCI in STEMI.
This guideline was developed with @ACCInTouch in collaboration with and endorsed by @EmergencyDocs @NAEMSP @SCAI
Kitae (Tye) Chang retweeted
Resident: “I’m so happy today is my last day of ICU ever”
Makes me sad that residents have lost interest in ICU. Learning physiology and learnimg to take care of critically ill patients will make you a better anesthesiologist
Kitae (Tye) Chang retweeted
Periodic reminder that for most people with vasodilatory shock we should be targeting a MAP > 60 mmHg (not 65).
A lower MAP goal was associated with a shortened duration of vasopressors & possibly reduced mortality.
With vasopressors, less is truly more.
jamanetwork.com/journals/jam…
Kitae (Tye) Chang retweeted
Many of our patients in the ICU develop thrombocytopenia. Here’s how to diagnose it and manage it. Here’s a friendly reminder of when to transfuse platelets as well. 🎩 tip to the authors.
eddyjoemd.com/foamed













































