Stuck in the š race until AI replaces me Meanwhile trying to build apps people would actually use š²
Joined March 2023
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yes, letās do more stuff like this
GPT-Rosalind surfaced a new lead for drug discovery: could restoring cholesterol transport protect neurons from degeneration?
DCTN1 is a gene linked to Perry syndrome, a rare neurodegenerative disorder. In mouse-brain data, disrupting it increased expression of genes involved in making cholesterol. GPT-Rosalind suggested a possible explanation: cholesterol may not be reaching where neurons need it.
That gives scientists a specific mechanism to test and, if confirmed, a direction for developing new treatments for neurodegenerative disorders.
With @perturbai_tx and @scrippsresearch, a team of thousands of GPT-Rosalind agents worked in parallel, connecting gene-expression results from millions of mouse brain cells with scientific literature in just 32 minutes. Weāre now expanding this collaboration to identify new drug targets.
openai.com/index/scaling-ai-ā¦
added trials to weekly and yearly plans in my app. already got a few, but 4 out of 5 users cancelled. anyway, itās good to see users actually starting trials.
after the initial release, i got 0 subscriptions. then, after digging into analytics, i realized my free tier was too generous and people were using the app a lot without paying. i checked out competitors, reduced the free tier, improved the paywall and added trials.
the most fascinating part is the whole process. you feel like a researcher. you try things, gather data, form hypotheses, run experiments and repeat. what a time to be alive
Vlad retweeted
Last year I thought Threads was an existential risk to X.
When Meta puts its full weight behind something -- by injecting the app into Instagram, itās DEFCON 5:
You have to squeeze out every last drop of growth from all available surfaces to save the app.
However, I started to realize that the opposite was happening:
It was strengthening X.
If you look at any announcement by Zuck, you will see the most rude & toxic comments on the internet.
But when he makes those same announcements on X, people are thrilled about how heās pushing humanity forward. X is a place where people are excited about the future, so itās no surprise he and his top lieutenants are using it more than their own app.
Threads ā and Bluesky ā have effectively quarantined some of the worst people on the internet.
And so I had an epiphany: those apps are Xās anti-abuse systems.
thnx for the new roadster demo. now i can clearly see retards on the platform and who should be muted š
Jensen Huang said something in his speech in the UK that really resonates with me: donāt overthink things. take a step forward. and that step will lead to another step
man itās literally the motto of my life
i swear opus 5.5 feels like AGI
my apps started getting traffic but still had zero paying users. so i asked claude to investigate how users behave and why they arenāt subscribing
it came back with a detailed report, conversion funnels, key issues, and even competitor comparisons. now weāre implementing changes based on its findings to improve revenue
lesson: set up analytics from day one and donāt hesitate to ask claude to dig into your data
iāve been running Apple Ads for 2 days and got 300+ users but not a single subscription.
is that enough data to conclude the app wonāt make money or should i keep testing with more users?
tibo says theyāll fix it on dev day. will seeā¦
Interesting turn of history
OpenAIās biggest advantage was affordability and generous limits. Then Anthropic surpassed them on model quality with Fable. Everyone waited for Astra to bring Fable-level intelligence with OpenAI-level limits
Instead we got great intelligence that burns through a $200 plan in 1ā2 days
Now Opus 5.5 comes with higher limits and OpenAIās answer is a $500 tier
I donāt know who will pay more for worse models. Weāll see
how does opus 5.5 build these insane landing page animations in one shot?
anthropic, iām sorry for all the hate iāve thrown your way. iām back
you cooked
Interesting turn of history
OpenAIās biggest advantage was affordability and generous limits. Then Anthropic surpassed them on model quality with Fable. Everyone waited for Astra to bring Fable-level intelligence with OpenAI-level limits
Instead we got great intelligence that burns through a $200 plan in 1ā2 days
Now Opus 5.5 comes with higher limits and OpenAIās answer is a $500 tier
I donāt know who will pay more for worse models. Weāll see
Every new model drop gives me a weird productivity boost and makes me want to work harder for the next few days
No idea if itās dopamine or something else but it works like a charm
OpenAI and Anthropic can we just get incremental improvement releases every few days please
I have an unlimited access to Claude models at my 9-5 job. Iāve been using solely fable 5.1 xhigh and itās been kinda ok
According to opus 5.5 benchmarks itās better than fable even on high reasoning. Will see if the reports are true or misleading (as usually)
Claude Code life hack
If youāre struggling to read Claude Fable or Opus 5 output just add
āin short and clearā
Output style config barely works for some reason Claude still tends to write in this weird overcomplicated way
Those 4 words make it write like a normal person instead of a Klingon alien trying to write Shakespeare
