Wyatt Clark (@wtclark) header
Wyatt Clark (@wtclark) profile picture

Wyatt Clark

@wtclark
Joined October 2012
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In her Life Time Leadville Trail 100 MTB presented by Kenetik debut, Kate Courtney not only earned 1st place with a time of 6:48:55, but she SMASHED the course record that has been held since 2015! 🎉🔥 💪 way to dig deep, Kate!
Image from Leadville Race Series (@LTRaceSeries)
Image from Leadville Race Series (@LTRaceSeries)
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Mathieu (@miniapeur) profile picture
Mathieu
@miniapeur1 Jun 2025
Image from Mathieu (@miniapeur)
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Want quickly check whether your predicted protein structure makes sense? Make a Ramachandran plot.
Samrat Mukhopadhyay (@SamratLabMohali) profile pictureSamrat Mukhopadhyay@SamratLabMohali30 May 2025
It's important to note that it was the (incorrect) criticism of GN Ramachandran's (correct) collagen triple helix structure by Rich and Crick that impelled Ramachandran to think deeply about polypeptide stereochemistry and introduce the epic phi-psi plot, a.k.a. Ramachandran map.
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Yong Li (@fugapku) profile picture
Yong Li
@fugapku26 Oct 2024
I am #hiring bioinformatics scientists at senior and staff levels. Please share if anyone you know might be interested. illumina.wd1.myworkdayjobs.c… illumina.wd1.myworkdayjobs.c…   illumina.wd1.myworkdayjobs.c…   #JOB #Bioinformatics #Software #Algorithms #AI #MachineLearning #PhD #Genomics #DRAGEN #DRAGENArray @illumina
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Found my doppelgänger @iddux at #ismb2024.
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It’s amazing how productive I am with a cat laying on me.
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Enjoying Windows XP season out here in CA.
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We went for a night hike on Mt. Diablo and found some tarantulas and scorpions.
Image from Wyatt Clark (@wtclark)
Image from Wyatt Clark (@wtclark)
Image from Wyatt Clark (@wtclark)
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Image from Wyatt Clark (@wtclark)
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CAGI (@CAGInews) profile picture
CAGI@CAGInews3 Aug 2023
CAGI** Workshop, Boston, 9/29-10/1 -- Shaping the Future of Computational Genome Interpretation. Open for registration. genomeinterpretation.org/cag…
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I'm excited to announce our most recent publication analyzing the genotype-phenotype relationship in Metachromatic Leukodystrophy (MLD). genomebiology.biomedcentral.…
Predicting disease severity in metachromatic leukodystrophy using protein activity and a patient...

Predicting disease severity in metachromatic leukodystrophy using protein activity and a patient...

Genome Biology - Metachromatic leukodystrophy (MLD) is a lysosomal storage disorder caused by mutations in the arylsulfatase A gene (ARSA) and categorized into three subtypes according to age of...

link.springer.com
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I have to recognize the Gelb lab for leveraging their mass-spectrometry method to measure the ARSA activity of tested mutations, as well as the team at BioMarin who carried out the plasmid design, transfection of cells, and curation of patient data.
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An especially big shout-out to Marena Trinidad, co-first author, is warranted! Marena handled everything from data analysis to lab work, and is one of the brightest people I've had the pleasure to work with at BioMarin.
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