Bioengineering lab led by Dr. Ambika G. Bajpayee. Drug delivery to charged tissues such as cartilage, meniscus, intervertebral disc and mucosal membranes.
Boston, MA
Joined June 2019
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We're at #ORS2026 in Charlotte this week! The Bajpayee Lab is presenting our latest work on cartilage-targeted drug delivery for OA. If you're working on OA, biomaterials, or musculoskeletal therapies. Come find us! #Osteoarthritis #Biomaterials #Orthopaedics @ORSsociety
Recap on last week's seminar! Dr. Chris Evans, professor of orthopedics at the Mayo Clinic @MayoClinic, visited Northeastern University and gave a wonderful seminar talk. It was great to learn about his amazing work in osteoarthritis IL-1RA gene therapy!
We are excited to share our newest work by Dr. Boyer @Boyer_TL et al on engineered cationic Interleukin-1 receptor antagonist for OA treatment!
Our new review, led by Helna, which examines how extracellular vesicles (EVs) interact with key biological barriers, is online now!
sciencedirect.com/science/ar…
We are thrilled to share our latest work led by @Henry2833884 titled “Extended osteoarthritis pain relief with neosaxitoxin using alginate-core polymeric microparticles” published in @nanoscale_rsc
Link: pubs.rsc.org/en/content/arti…
Come see us at ICRS 2025 18th World Congress in Boston! Dr. Bajpayee and Helna Baby will present our works on Extracellular Vesicles (EVs) at session 1.1 elEVate Your Game of ICRS 2025 (Sat 10/11) #ICRS #Cartilage
Congratulations to Dr. Timothy Boyer @Boyer_TL for successfully defending his doctoral thesis! Tim’s work has focused on designing cartilage targeting cationic fusion proteins for the treatment of OA. Tim is heading to Rush University for his postdoc! He will be missed very much!
By combining experimental and computational approaches, we investigated the contribution of charge and hydrophobicity arrangement on cationic peptide’s intra-cartilage transport. We found that there is an optimum cationic peptide's residue configuration for cartilage targeting.
We are thrilled to share our latest work titled "Spatial charge-hydrophobicity configuration modulates cationic peptide transport in cartilage," published in @BiophysJ
Free access: authors.elsevier.com/c/1lsw9…
