Biochemistry of immunology, protein structure and protein folding. Flipping the classroom into the digital world for Tulane students and everyone else.
Tulane University
Joined April 2013
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- Following55
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- Likes372
Sam Landry retweeted
Based on pioneering work by @BAGarvy and Fran Lund that B cells are key antigen presenting cells for Pneumocystis (a common fungal pneumonia in infants), @MNoell_12 figured infants must have anti-fungal IgMs that predict T cell responses. They do! insight.jci.org/articles/vie…
Sam Landry retweeted
This is why 2nd boosters should be available for all health care workers now. A report on ~30,000 Israeli HCWs indicates 65% lower risk of breakthrough infections during the Omicron wave (4 vs 3 doses) @JAMANetworkOpen
jamanetwork.com/journals/jam…
Sam Landry retweeted
Just published @NEJM
During Omicron, the 2-shot mRNA vaccine effectiveness among >250,000 children age 5 to 11 years old:
vs hospitalizations was very high—83%
vs PCR confirmed infections 65%
nejm.org/doi/full/10.1056/NE…
Sam Landry retweeted
Although the handshake and other types of physical contact are gradually returning, they have been on hiatus due to #COVID19. Such changes have already altered the epidemiology of a range of infectious diseases.
Learn more in a new #SciencePerspective: fcld.ly/al7glzl
Sam Landry retweeted
Researchers know little about the global diversity and distribution of #soil fungi
To change that - @spununderground - a new nonprofit is funding a global network of subterranean sleuths
Learn more: science.org/content/article/… via @ScienceMagazine
Sam Landry retweeted
What is immune imprinting and why it is important?
A superb explainer
“Our first encounter with the spike antigen, either through infection or vaccination, shapes our subsequent pattern of immunity through immune imprinting" —@BoytonRosemary
ft.com/content/4f71ac72-0aff…
Sam Landry retweeted
When it comes to #SARSCoV2 and Covid, it's important to keep your eyes on the ball. The ball is BA.5 and here is what we know about it
erictopol.substack.com/p/the…
Sam Landry retweeted
A new report on Covid reinfections is particularly concerning. I've written about it here erictopol.substack.com/p/a-r…
Sam Landry retweeted
Gov Edwards @LouisianaGov What a great selection is the the Gulf Frittillary for our state butterfly.
Sam Landry retweeted
Really interesting paper from the Kelsoe lab showing that only a fraction of phenotypic GC Tfh cells" are actually in the GC, and the two different types of GC Tfh cells have different patterns of proliferation and cellular function. cell.com/immunity/fulltext/S…
Sam Landry retweeted
Incredible the speed of analysis of new variants, in 2 weeks we did a full analysis and wrote a preprint but we need to drop that time to less than a week for future VoCs. Omicron has high propensity for open state, immune escape on 28% of Abs tested.
Sam Landry retweeted
Prior common colds with coronaviruses were supposed to have some protective effect for Covid. That turns out to be just the opposite
cell.com/cell-host-microbe/f… @cellhostmicrobe
Sam Landry retweeted
"SARS-CoV-2 Beta Variant Substitutions Alter Spike Glycoprotein Receptor Binding Domain Structure and Stability"
@TulaneNPRC @MossDanL @TulaneMedicine
#SARSCoV2 #COVID19
jbc.org/article/S0021-9258(2…
Sam Landry retweeted
Things deteriorating here in New Orleans. Storm stalled. NWS updates are worthless. My guess is that this is the turn with the westerlies. We have to wait for it to take off east and the eye passes right over us. #IDA #HurricaneIda #NWS
Sam Landry retweeted
Thank you! I’m honored to have such a great mentor!
Big congrats @casso89 for winning the SAIS prize for best PhD thesis in lifescience! During his productive time in my lab, he studied a variety of CD4 T cell responses: to therapeutics, viruses, commensals and pathogenic bacteria. Well deserved!
Sam Landry retweeted
Of 25,000+ people who tested positive for #COVID19 in Germany, 8% had very high viral loads; about a third of these had little to no symptoms. The results suggest asymptomatic people can be expected to be as infectious as hospitalized patients @c_drosten fcld.ly/tx0vn7z
Sam Landry retweeted
Our latest metanalysis of SARS-CoV-2T cell epitopes combines results from 25 different studies. 1400 epitopes for thus far defined from the worldwide scientific community studying CD4 and/orCD8 T cells . cell.com/cell-host-microbe/f…
Sam Landry retweeted
The humble pipette tip is tiny, cheap, and utterly essential to science.
But now, due to a series of ill-timed breaks along the pipette tip supply chain has created a global shortage. buff.ly/2R6WtEi
Sam Landry retweeted
I’m excited to share our study in @ImmunityCP using antibody engineering to help understand how antibodies protect against #Ebola. An amazing collaboration between @ragoninstitute @EOSaphire @TheBukreyevLab @K_G_Andersen, Tulane and Kenema Govt Hospital authors.elsevier.com/c/1cu~c…
Sam Landry retweeted
1) SARS-CoV-2 Vaccines - I promised a Tweetorial and here we go. This is going to be long and nerdy. But I'll make sure it is easy to understand. If you want more details, please just read this: nature.com/articles/s41586-0…