Research group focused on developing affordable biotherapeutics and diagnostics for neglected tropical diseases based on monoclonal antibodies
DTU Bioengineering (Lyngby)
Joined August 2020
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Center for Antibody Technologies retweeted
A promising #snake venom #antibody that failed testing is good news for developing a broad-spectrum #antidote. New research from i.a. Danish & Costa Rican scientists in @NatureComms. @CAT4Science @UniversidadCR @AndreasLaustsen @CVSoerensen #Immunology dtu.dk/english/newsarchive/2…
Exciting News! - Yesterday our newest paper was published in @NatureComms by @CVSoerensen, @AndreasLaustsen and many more. The study unveils highly surprising research findings on snakebite envenoming therapies that call for caution. Full study: nature.com/articles/s41467-0…
Thanks to all collaborators and funders including @DTUtweet @DTUbioengineer @DTUBiosustain @wellcometrust @VILLUMFONDEN @novonordiskfond @ERC_Research @UniversidadUCR
We are happy to share the publication of a new book on #phage display in @SpringerNature, where Tulika and @AnneLjungars describe #deep mining methods for the discovery of #rare #antibodies.
link.springer.com/book/10.10…
Typically, #whole cell selections result in discovery of antibodies against highly expressed cell surface receptors. Here, we present detailed protocols on phage display selections, utilizing #depletion or #blocking, for discovery of #rare #antibodies against multiple targets.
Thanks to Michael Hust and Theam Soon for making us part of this, to @CAT4Science team, @DTUbioengineer, @DTUtweet, @AndreasLaustsen for your support, to employees at @BioInvent and @mats_ohlin for the fruitful discussions, and @wellcometrust and @ERC_Research for funding!
The sun is shining in Denmark and besides our passion for science we also love and enjoy moments together by having a barbecue or flowing down the river on a canue! Have a look at some of our moments together 😊
Center for Antibody Technologies retweeted
Podcast: A few months ago, I had the pleasure of doing this @REBBLS Podcast with @JornEmborg, where I got to tell about my career as both an #academic and #biotech #entrepreneur, as well as how to bridge these two worlds: open.spotify.com/episode/44m…
Last week @jack_wade6 successfully defended his PhD thesis about "Engineering and structural characterization of cross reactive, pH sensitive antibodies against long chain alpha-neurotoxins". Thank you for the last three years and we wish you can continue your successful path!🥳
Further, we thank @DTUtweet, @DTUbioengineer,@VILLUMFONDEN, @wellcometrust, @ERC_Research for the support to realize this project.
We are happy to share a new paper in @CellRepMethods by @AnneLjungars about her previous work at @BioInvent and @lunduniversity regarding #antibodydiscovery using #computational modeling combined with #antibody #phage display and #NGS
shorturl.at/oAJ34
We have prepared a thread about our new #preprint about pH-dependent binding antibodies and how cool this is on #antivenom development. Thanks to
@ERC_Research
for the generous funding and to all our colleagues
@DTUtweet
@DTUbioengineer @Oslounivsykehus
shorturl.at/beEY9
We are excited to share our #preprint “Phage display assisted discovery of a pH-dependent anti-alpha-cobratoxin antibody from a natural variable domain library”!
Read: biorxiv.org/content/10.1101/…
We are excited to share our #preprint “Phage display assisted discovery of a pH-dependent anti-alpha-cobratoxin antibody from a natural variable domain library”!
Read: biorxiv.org/content/10.1101/…
Our study shows that histidine doping may not always be necessary to achieve pH-dependency in antibodies. Plus, given the high diversity available in a naïve antibody library, it can likely be applied to discover pH-dependent antibodies against a wide range of antigens!
Thank you @DTUbioengineer @AndreasLaustsen @LLedsgaard @markthebanana @AndersenJT and @CAT4Science team for your help with this study! 🧬🥽