CMLBTM retweeted
Scientists found a way to flush Alzheimer’s plaque out of the brain in minutes.
Without any surgery and drugs.
Your brain has a waste-clearance network called the glymphatic system. It flushes out toxic proteins and dead cells.
But it only really activates during deep, slow-wave sleep.
If you don't sleep, the trash piles up. Over time, that buildup leads to cognitive decline and Alzheimer's.
Until today.
Researchers just published a paper proving they can manually trigger this cleaning cycle.
Without you ever going to sleep.
They used 40.68 MHz ultrashort waves (USW) beamed non-invasively into the brain.
Within 10 minutes, the brain's fluid flow rapidly accelerated.
The waves artificially synchronized the neurons into a Delta state, the exact frequency of deep sleep. This forced the brain's water channels to open and start flushing out the system.
They tested it on mice with traumatic brain injuries and Alzheimer's pathology.
The brain swelling dropped. The toxic proteins were cleared out. Cognitive deficits actually improved.
No surgery. No massive chemical interventions. Just a frequency.
CMLBTM retweeted
人間の幹細胞から育てた「ミニ脳」を人型ロボットの頭脳として組み込めたとの報告です。
同じ練習量の通常のニューラルネットワークより成績が良く、消費エネルギーも少ないそうです。
①ロボットのカメラが見た映像を電気刺激の模様に変換
②ミニ脳に送る
③返ってきた神経の反応を読み取る
④「左手でつかむ」「前に進む」といった指示に変える
という仕組みです。
インディアナ大学の研究者らによる報告。
ミニ脳は3か月かけて育てた直径数ミリほどの神経組織で、電極チップの上に載せられています。
文字ブロックの「I」なら左手、「U」なら右手でつかむという課題では、約9割の正解率。
繰り返し練習すると成績が上がり、しかも予めレーザー追跡で練習したミニ脳は、初めての「つかむ」課題でも練習なしのものより高い正解率を出しました。
なお、培養装置や計測機器はまだ大がかりで、ミニ脳の個体差や再現性といった課題も残っています。
そして研究者らは、倫理面の議論も慎重に進める必要があるとしています。
CMLBTM retweeted
HOLY SHIT
for the first time ever, a human has been injected with a treatment designed to rewrite their DNA directly INSIDE their body using prime editing
if it works, it would be the first time prime editing has successfully corrected a genetic mutation directly inside a living human
CMLBTM retweeted
Okay this is genuinely insane.
SpaceX just unveiled a satellite whose only job is to run AI. Not internet. Not GPS. Just compute, floating in orbit.
It's called AI1, and the reason behind it breaks your brain.
AI data centers on Earth are hitting a wall, not a chip wall, a physics wall.
They need staggering amounts of power and water just to stay cool, and we're running out of grid and land to build them.
So Musk's answer is: stop building them on Earth.
In orbit, the sun never sets. Free power, 24/7. No water for cooling, you just radiate heat into the vacuum of space. The two things choking AI on the ground barely exist up there.
And here's the wild part: Musk says it's easier to build than a Starlink satellite. Strip out the complex antennas and it's "a lot of solar cells, a radiator, and some laser links."
One AI1 carries the compute of an Nvidia GB300 rack, the same hardware data centers fight over down here.
AI1 is just the first one. The plan is a constellation of up to a million of them.
And the timing isn't an accident, SpaceX goes public this week at a ~$1.75 trillion target. This isn't a rocket company anymore. It's positioning itself as the power grid for AI, in space.
The race for AI compute just left the planet. Literally.
CMLBTM retweeted
Interim ER-100 trial results are out 👀 The Phase I trial is designed to evaluate safety & tolerability, not to demonstrate efficacy. Grateful to participation of the patients in the trial 🙏
CMLBTM retweeted
Breaking
lifespan.com/blogs/magazine/…
CMLBTM retweeted
BlenderベースのAIネイティブ3Dエディター『Mixar』が面白い
複数のAIエージェントが地形・建物・小物・ライティングなど、シーンの異なる部分を同時並行で制作
大規模な3Dシーンを一気に組み上げる。修正したい場所は直接描き込んで指定可能。
生成されたモデルも実際に編集できる3Dメッシュです
🤝 Paid partnership
Disney would've loved this in 1995.
Today we're launching @mixie3D. (And yes, we made this entire film in it.)
Making 3D has always meant one person doing a dozen jobs. Now a team of AI agents does them at once.
Tell Mixar what you want. Agents model, texture and light the scene at the same time, and you can step in and change anything.
CMLBTM retweeted
Un robot trabajó una hora entera en una lavandería sin que nadie lo tocara.
Cargó la lavadora y la secadora, las prendió, sacó las toallas, las dobló y las acomodó en los estantes.
Y cuando se le cayó una toalla al piso, no la dobló. La echó otra vez a la ropa sucia.
Lo grabó Dyna Robotics, una startup en la que invirtieron NVIDIA y Amazon. El video va acelerado y el reloj de abajo marca la hora real.
Su CEO dice que los clientes necesitan robots que trabajen un turno completo "sin niñeras humanas".
El siguiente paso es llevar a este robot a lavanderías de clientes.
CMLBTM retweeted
Claude acaba de encontrar algo en el ADN que los humanos no habíamos identificado.
Un sistema biológico desconocido, escondido en virus que infectan bacterias, con una estructura que recuerda a CRISPR.
Detectó el patrón, investigó si alguien lo había descrito y lo puso sobre la mesa de un laboratorio.
Todavía no sabemos para qué sirve.
Pero la escena ya es brutal: una inteligencia creada por nosotros, leyendo la vida y señalando algo que se nos había escapado.
Le enseñamos nuestros idiomas. Ahora empieza a descifrar el de Dios.
Claude has discovered a previously unknown enzyme system hidden in the DNA of bacteriophages. Beside the enzyme’s gene sits a long array of repeating DNA—a structure that looks somewhat similar to CRISPR.
We don’t yet understand what this system does, but only a handful of known systems share its features, and all of them are able to cut, copy, and paste DNA. Historically, the discovery of such programmable systems has helped revolutionize medicine. CRISPR, for instance, is now the foundation of genetic medicines. But it will take much more work to learn what this system does, and whether it can be put to similar use.
Read more: anthropic.com/news/claude-di…
CMLBTM retweeted
新しいAI「JING」が誕生。このAIはリアルタイムで「動ける世界そのもの」を自動生成。
「AIに画像や動画を作らせる時代」はもう終了。「AIがその場で完全な世界を作り、人間が一人称視点で中を自由に動き回れる時代」が始まってしまった！こんな世界にして」と伝えるだけで、無限の空間（オープンワールド）が秒で組み上がる。
仮想空間に、人間がVRやPCを通じて「もう一つの現実」に完全に入り込み、理想の世界で自由に暮らせるバーチャル宇宙への扉がガチで開いた。
CMLBTM retweeted
Elon Musk told Ron Baron he's building a chip 2 to 3 times better than Nvidia, at 10% of the cost.
I have the entire physical design of the chip laid out in memory. I can visualize the whole thing.
No CAD software, no design team walking him through it, just memory.
When TSMC told him a new fab takes 5 years he said: "five years to me is an eternity. My timelines go one year, two year, and at year three it goes to infinity."
So he's building his own
Same mindset runs the factory floor. Tesla's cycle time per car is already down to 35 seconds, with a target of 10.
Tesla's self-driving has logged 10 billion miles, 4 times safer than a human driver. With the new chip it'll be 10x.
I don't own any vacation homes. Just one house in Austin and a tiny house at Starbase. Friends come to visit and they think I'm kidding.
Watch the full conversation ⤵
CMLBTM retweeted
卧槽！OpenAI前大佬离职创业，孵化出了过去 2 天美国最火的 AI 大模型 Jev ！它没办法生成文字，没办法生成图片，唯一做的就是一个非常简单的事情：帮你快速做判断。
比如说，决定一只股票要不要买，查询 1 个到目的地最性价比的航班，决定一个决策是否正确，并且决策速度是白毫秒级别。Jev 由 OpenAI 的大佬创业两年训练出来，押注的却是和 GPT 完全不同的 1 个方向，并且在砍掉各种文字和图片生成功能之后，获得了极致的快速度和低成本。
目前在这个官网就可以申请：typesafe.ai/，或者也可以在 vercel 上自主调用。准备把它列入 Grok bot ，帮助我在某些场景做快速的判断和打标
After co-inventing ChatGPT, I kept asking myself: why have superhuman chat models not led to AGI?
I’ve spent the last 2 years in stealth building a new way to train models (RLCD), and a new type of frontier AI model that we are releasing today: Jev
• 20-200x faster
• 40-400x cheaper (w/ output tokens free)
• Frontier composable intelligence optimized for decisions
AFAICT the shortest path to AI-based economic revolution
CMLBTM retweeted
Elon Musk y su empresa Neuralink han conseguido leer la mente. Es un hito histórico que cambiará la vida de mucha gente.
Piensas algo y la máquina es capaz de leerlo y reproducirlo. Aquí un hombre que le vuelve a decir “te quiero” a su esposa después de muchos años mudo. ❤️
CMLBTM retweeted
NEW 🚨: Scientists now believe the brain might process information using tiny quantum vibrations instead of relying only on electrical signals, potentially making thinking much faster.
ALT NEW 🚨: Scientists now believe the brain might process information using tiny quantum vibrations instead of relying only on electrical signals, potentially making thinking much faster.
ALT NEW 🚨: Scientists now believe the brain might process information using tiny quantum vibrations instead of relying only on electrical signals, potentially making thinking much faster.
CMLBTM retweeted
166,700 fruit fly neurons just took over 3 drones, and nobody taught them to fly.
Scientists mapped the full brain of 1 real fly, every neuron and all 25 million connections, and put it online for free.
Someone copied that brain 3 times and plugged each copy into a drone.
No flight code, no gesture presets, no "avoid the chair" rule, just a camera feeding the fly's eyes and neurons turning into throttle.
1 drone hovers, 1 slips past a chair, 1 drops to the floor and holds.
This brain spent 350 million years learning to stay in the air, and now it's back where it belongs.
No GPUs, no training run, no $100B data center, just a brain smaller than a grain of salt.
1 fly gives you 3 pilots, and 1,000 flies give you a swarm.
The fly is dead, but its brain just got a squadron.
166,700 fruit fly neurons are flying a drone around my bedroom.
1 camera watches my open hand and that's the whole input.
The panel in the middle is the brain running live 166,700 neurons, 25 million connections, the full reconstructed map of a fruit fly's head.
Camera reads the hand, the brain fires, the output becomes throttle.
Open palm and it climbs, fist and it holds, drop the hand and it comes down.
4 propellers the size of a coin hanging off a nervous system that belonged to an insect.
The honest part this is a computational model, not a resurrected fly, the wiring is biological, the drone is mine, I built the bridge between them.
I never wrote flight logic, no PID tuning, no gesture presets, I gave the neurons somewhere to send the signal and they found the ceiling.
11 seconds in, it holds altitude on its own.
The fly is dead and it's still flying.
Readers added context they thought people might want to know
The quoted demo shows one drone whose throttle is set by hand gestures via camera and hand-tracking code; pitch, roll and yaw stay on a physical remote, with no closed-loop autonomous flight. No footage shows 3 drones independently navigating or avoiding a chair. x.com/i/status/20996… github.com/pattssun/iDrone
CMLBTM retweeted
166,700 fruit fly neurons are flying a drone around a bedroom right now.
One camera watches an open hand. That's the entire input. The panel in the middle is the brain itself, running live, 166,700 neurons and 25 million connections, the full reconstructed wiring of a fruit fly's head.
The camera reads the hand, the brain fires, the output becomes throttle. Open palm and it climbs. Fist and it holds. Drop the hand and it comes down.
Four propellers the size of a coin, hanging off a nervous system that used to belong to an insect.
Here's the honest part. This isn't a resurrected fly. It's a computational model built from real biological wiring, bridged to a drone the builder made themselves. What nobody wrote is the flight logic. No PID tuning, no gesture presets, no code telling it how to hold altitude. They gave the neurons somewhere to send a signal, and it found the ceiling on its own.
Eleven seconds in, it's holding altitude by itself.
The fly is dead. It's still flying.
CMLBTM retweeted
OpenAI ve Anthropic gibi şirketlerin "yapay zeka işlerinizi elinizden alacak" anlatısı tesadüfi bir endişe değil, son derece bilinçli ve stratejik bir korku pompalamasıdır. Amaçları distopya satıp regülatörleri arkalarına almak, açık kaynaklı modellerin önünü kesmek ve pazarda bir tekel yaratmaktır.
Tarihsel veriler net: Bugüne kadar hiçbir teknolojik devrim insanlığı kitlesel olarak işsiz bırakmadı; aksine verimliliği artırarak her zaman yeni iş kolları yarattı. Yapay zeka da eninde sonunda hayatımızın ayrılmaz bir parçası ve sıradan bir emtia (commodity) haline gelecek. İnsanlığı kenara itmeyecek.
Peki bu korku senaryosunun altındaki asıl oyun ne? Literatürde buna "Merdiveni Çekme" (Kicking Away the Ladder) taktiği diyoruz.
Ekonomist Ha-Joon Chang tarafından literatüre sokulan bu kavramın temeli şuna dayanır: Bugünün gelişmiş ülkeleri, zamanında kendi endüstrilerini katı korumacı politikalarla büyütmüş, zirveye yerleştikten sonra ise gelişmekte olan ülkelere "serbest piyasa kurallarını" dayatarak aynı yoldan zenginleşmelerini engellemiştir. Kısacası, zirveye ulaştıktan sonra arkandan gelenlerin çıkamaması için bizzat kullandığın o merdiveni tekmelersin.
Bunun şirketler dünyasındaki karşılığı tam olarak bugün yaşananlardır. Regülasyonsuz bir ortamda agresifçe büyüyüp pazar payını konsolide eden bir firma, gücünü sağlama aldıktan sonra aniden sektöre ağır regülasyonlar getirilmesi için lobi yapmaya başlar. Bu lobi faaliyeti genelde "kamu güvenliği", "etik" veya "sistemik riskler" kılıfına sokulur.
Ancak asıl amaç etik değil, bariyerdir. Piyasaya yüksek maliyetli yasal bariyerler örerek, yeni girecek start-up'ların veya açık kaynak (open-source) projelerin rekabet etmesini imkansız hale getirmek isterler.
Bugün yapay zeka devlerinin "bizi acil regüle edin" diye bağırmasının temelinde yatan strateji tam olarak budur.
CMLBTM retweeted
By now, it's amply clear that the big bosses of US frontier AI labs are really, really scared of China.
And, fascinatingly, part of the answer why might be a tiny place in Inner Mongolia that you've probably never heard of: Ulanqab prefecture.
Heard of it? Didn't think so.
Even myself, who's traveled to Inner Mongolia twice, had never heard of it before researching this story.
This is because, at first glance, this place is pretty unremarkable. Check its Wikipedia page (en.wikipedia.org/wiki/Ulanqa…) and you’ll see the only thing it’s famous for is being the birthplace of He Pingping, who briefly held the Guinness record for world’s shortest man.
That’s it, that’s the list!
Otherwise, it's just a sparsely populated - 1.5 million people, minuscule by Chinese standards - stretch of windswept grassland on the Mongolian plateau.
Except there is one number that tells you there is more to this place that meets the eye: this tiny prefecture consumes nearly 1% of all of China's electricity - and that number is growing by double digit numbers every year.
And yes, I did write **consume**, not produce.
In fact, when you divide Ulanqab's electricity consumption by the number of households living there, each household in this remote corner of Inner Mongolia "consumes" about 105,000 kWh in electricity, roughly 10 times the U.S. average. Insane electricity consumption numbers.
So what are the Ulanqabese doing? Are they all running 10 American households' worth of appliances?
Here is another number that might clue you in on the answer: over the past few years, this unremarkable prefecture has quietly signed over half a trillion yuan (and, yes, that’s trillion, with a "T") worth of investment deals from all the major Chinese tech giants.
What is going on, you'll have guessed by now, is the most ambitious data center buildup anywhere on earth - and it's really surprising this hasn't been talked about more because the scale is beyond anything else, and by an immense margin.
Take Elon Musk's so-called "Colossus" datacenter in Memphis, Tennessee which he pitches as "the world’s largest AI supercomputer."
According to their own numbers (x.ai/colossus), Colossus has 200,000 chips, which, let's be clear, is already super impressive.
In datacenter lingo, this converts to roughly 5000-6000 "racks": you know, the fridge-sized cabinets full of blinking lights you see in every movie scene set in a server room.
How many racks are they building in Ulanqab? Over 5 million.
Yes, about one thousand times the scale of "Colossus" 🤯
I tripled-checked the number: it is indeed the official number published by authoritative sources such as "Science and Technology Daily", the official newspaper of China's Ministry of Science and Technology (stdaily.com/web/gdxw/2026-08…).
This is an absurdly large amount of compute.
What we see appearing in this Inner Mongolian steppe may be the closest thing to a world brain humanity has ever built - a place where a large share of the world's thinking will physically happen.
And - as we'll see - what makes this story so fascinating is not just the scale, but why it's getting built in this particular patch of Inner Mongolian grassland which combines a number of characteristics unlike anywhere else.
If you believe, as I do - and as both China and the US obviously do as well - that AI will be the defining technology of the 21st century, this makes Ulanqab one of the single most relevant geopolitical places in the world right now.
The full story - the Chinese government plan Ulanqab is part of, energy prices, chips and the strategic questions this raises - is here: arnaudbertrand.substack.com/…
CMLBTM retweeted
卧槽，美国人真有意思
在洛杉矶的 All-In Summit 大会上
黄仁勋的手机突然响了
是特朗普打来的
黄仁勋接起电话
给切成了免提....
特朗普当着几千人说，AI 危险论和反对建数据中心都是"骗局"，黄仁勋在旁边一直附和...
黄仁勋上手忙脚乱找免提，特朗普调侃："Jensen 造得出十年没人能抄的芯片，却不会开免提。"
哈哈哈哈
然后特朗普一顿疯狂输出：
- 反对建数据中心的声音是"阴谋"，最高兴的是中国
- 数据中心能让老百姓富、各州富，是"未来二十几年的石油"，比互联网还大
- 反对的人正中别人下怀，可能是搞政治的，也可能是中国
- 黄仁勋："您说得对，我们不会让它得逞。"
特朗普说：“机器人不会接管世界。AI 也不会。这整件事是个骗局。”
还顺带提了自己叔叔在 MIT 当了 40 多年教授，自称"有遗传，懂 AI"。
他随后画风一转说：要"稍微小心、稳妥地做"，但不会因此叫停整个产业。有句口头禅是"谁赢了 AI，谁就赢了"。
结束，他夸黄仁勋和 David Sacks 干得好。最后又说美国有 20 万亿美元投资正在进来，拜登那会儿连 1 万亿都不到。
黄仁勋全程附和，回应说：
"您说得对，我们不会让那种事发生。我们会确保美国在 AI 竞赛中，每个行业、每家公司、每个州、每个人都赢。"
