
Stripe cofounder @collision interviews founders, builders, and leaders over a pint.
The pub
Joined October 2026
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Scott Nolan joined John Collison to discuss @generalmatter’s bet on domestic uranium enrichment, the SpaceX approach to heavy hardware, the structural flaws of cost-plus contracts, and why fuel cost is the real bottleneck for advanced reactors.
00:00:00 Introduction
00:00:41 America’s missing nuclear fuel
00:05:27 Why small reactors need stronger fuel
00:11:42 Can nuclear power the AI buildout?
00:15:25 Why nuclear became so expensive
00:22:24 The startups reinventing nuclear
00:25:31 General Matter’s race to 2030
00:29:44 Stripe Press’ new books
00:30:22 The SpaceX playbook applied to nuclear
00:35:18 Uranium enrichment, explained
00:45:53 How small startups beat stagnant incumbents
@ScottNolan @collision
Cheeky Pint retweeted
You’ve seen the show, now play the (unofficial & unauthorized) game with all the 8-bit Guinness you can drink. Kudos @ambrook for a typically delightful experience!
ambrook.com/experiments/pint
“The thing that people forget is that nuclear is by far the cleanest and safest baseload. It’s actually safer than wind power per terawatt-hour.”
“If you look at all downstream mortality, [wind power is] more dangerous than nuclear. And then, if you look at all downstream CO₂ emissions, nuclear is actually the lowest—lower than wind or solar.”
“The one thing nuclear has not done a good job of in beating everything else is on cost. And so I think that’s actually what it all comes down to.”
@scottnolan @collision
Spotify: open.spotify.com/episode/1gB….
Apple Podcasts: podcasts.apple.com/us/podcas….
YouTube: youtube.com/watch?v=QsL2BIvR….
Substack: cheekypint.substack.com/p/th….
Cheeky Pint retweeted
General Matter CEO @ScottNolan joined me to break down why enriched uranium is the bottleneck for nuclear power. We get into why US nuclear fuel comes from Russia; their enrichment facility in Paducah, Kentucky; applying the SpaceX playbook to heavy industry; and the reasons nuclear became expensive.
00:00:00 Introduction
00:00:41 America’s missing nuclear fuel
00:05:27 Why small reactors need stronger fuel
00:11:42 Can nuclear power the AI buildout?
00:15:25 Why nuclear became so expensive
00:22:24 The startups reinventing nuclear
00:25:31 General Matter’s race to 2030
00:29:44 Stripe Press’ new books
00:30:22 The SpaceX playbook applied to nuclear
00:35:18 Uranium enrichment, explained
00:45:53 How small startups beat stagnant incumbents
Sam Altman on why kids growing up with AI will never be mind-blown by what it can do:
“We had to suffer when I was a kid to make a piece of software that barely did anything. And now you can have a full 3D video game—anything you can think of—in 10 minutes.”
“That reminds me of the early internet. They’re never going to be mind-blown by that, because that’s always what they expect out of the world.”
“Any ideas they can come up with, anything they want to create, anything they think might be useful—the computer’s supposed to make it.”
@sama @collision
Cheeky Pint retweeted
Tomorrow on Cheeky Pint: @ScottNolan of uranium-enrichment startup @generalmatter
Sam Altman on benchmaxxing:
“Maybe there are two things we should really care about models being good at. One is, scientific discovery and doing things that people cannot do. The other is being enjoyable to work with. I don’t think we have great benchmarks for being enjoyable to work with. I’m actually not sure we have great benchmarks for the smartest, scientific scientist either. But, we endeavor not to benchmaxx.”
“I keep thinking that benchmaxxing is over as a phenomenon, and people keep doing it.”
@sama @collision
“People give different numbers for the cost per gigawatt measured in the five-year total cost of ownership right now. Let’s pick $70 billion as a number.”
“I think if that number were 20 instead of 70, we should be much happier and we should still demand to get 10x better performance out of it with smarter models every year.”
@sama @collision
“I bet we could redo Navier-Stokes at 1/100th of the cost a year from when it was done.”
@sama @collision
“People just didn’t think the model was going to do these things. We had this collective experience of watching people’s hardest research problems from their academic careers—the model was just knocking them down, one after another. Across many different fields, it was incredible to watch.”
“I was tremendously excited and happy. But I also had much more sadness and melancholy—a feeling of something ending—than I was expecting.”
@sama @collision
Sam Altman on OpenAI almost abandoning token pricing:
“We almost made what would’ve been a bad call to say we’re not going to price our next model in tokens at all. You’re just going to give it a prompt, and we’re going to give you a price back. It’s going to be like AWS to just do something and we send you a bill. But the customer response on that is so negative.”
“They’re like, ‘I need to know what I’m paying for somehow.’ I asked a few people, ‘Would you rather pay more for the same output, but have it priced in some number of consistent tokens? Even if we inflated the tokens?’ And they’re like, ‘Oh, I’d much rather you inflate the tokens and pay more. Because I know there’s a real thing there.’”
“So I think you are right, people don’t just want us to give them a price, because they feel like over the long term they’re gonna get screwed somehow. In the same way that maybe people would rather pay for CPU hours rather than just getting their thing done, even if it was less expensive.”
@sama @collision
Sam Altman joined John Collison for a pint to discuss the scaling laws of agent teams, proving Navier-Stokes, why hand-written software will soon look quaint, the optics of token pricing, and what computing looks like beyond the keyboard and screen.
00:00:00 Introduction
00:00:12 PHP week
00:02:37 Internet early days
00:07:33 Cyber Blue
00:08:54 Sandboxing
00:15:47 Math
00:23:12 Agent swarms
00:24:48 Stripe Atlas
00:25:17 Compute
00:37:53 Revenue per gigawatt
00:49:27 Token pricing is fake
@sama @collision
Cheeky Pint retweeted
OpenAI’s @sama joined me at the pub (and had his first Guinness) to discuss the PHP exploit, math weekend at OpenAI, agent swarms, and how he thinks AI leads to deflation.

