Danielle Hammond, MD (@DanielleHammo20) header
Danielle Hammond, MD (@DanielleHammo20) profile picture

Leukemia doc at MD Anderson 🇺🇸 focusing on MDS-CH-VEXAS. Ex-pat 🇨🇦. Believe in the transformative power of compassion and science. Love puns! Views my own.

Houston, TX
Joined November 2015
Danielle Hammond, MD retweeted
#ASH26 #AML #leusm Cladribine with low dose cytarabine plus venetoclax compared with intensive chemotherapy with 7+3 for patients aged ≥ 60 years with newly diagnosed AML onlineprogram.hematology.org…
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Danielle Hammond, MD retweeted
What happens in the bone marrow clonal dynamics during sepsis? We studied by looking at emergency hematopoiesis in the ICU setting 👇@ClevelandClinic @Yale #CHIP @aamdsif @MDSFoundation @olisaogbue
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Danielle Hammond, MD retweeted
Today is MDS World Awareness Day. This year, YOU told us that Understanding Your Treatment Options is what our community wanted to see in the spotlight. Today, we are sharing this resource, created in response to what you told us matters most to you. bit.ly/4zwkKnh
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Danielle Hammond, MD retweeted
🔗 Check the #Leukemia #Insight where we review the current landscape of #CML therapies 💊 & discuss the clinical trials available now at @UTMDAnderson If you have any questions ❓️or are interested by a particular study, feel free to reach out to me. view.e.mdanderson.org/?vawpT… – at Timberwood Park, TX
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Grazie to the San Raffaele Scientific Institute for hosting the 3rd International VEXAS Workshop. Great learning, collaboration and hope. #VEXAS #MDS #DADA2 @bhavishap29 @emmamgroarke @fergutierrezro1 @doctorpemm @UTMDAnderson 🧬 📚 💡
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Back when I was a fellow Dr. Zeev Estrov at MDACC used to say (nearly at every tumor board discussion about an AML case) “it’s all about the monocytes” The man had a point!!!!! It’s all about RAS (at least nowadays 😉) #IYKYK
Read: "RAS Pathway Activation Is a Hallmark of Myeloid Sarcoma," by authors Bettina Nadorp, Audrey Lasry, Sanam Loghavi, Iannis Aifantis, and Ann-Kathrin Eisfeld. aacrjournals.org/bloodcancer… @BettinaNadorp @audrey_lasry @sanamloghavi @iannisaifantis1 @AkEisfeld
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Danielle Hammond, MD retweeted
➡️🧬Check out our case series describing outcomes of adult patients with Li Fraumeni syndrome who developed myeloid neoplasms: ➡️ Some good outcomes, but a lot more to be done. @JournalCancer @AmericanCancer @UTMDAnderson acsjournals.onlinelibrary.wi…
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Danielle Hammond, MD retweeted
A pilot study at @UTMDAnderson is evaluating the safety and tolerability of low-dose sirolimus in adults with RUNX1-FPD. Additional study measures include platelet counts, bleeding symptoms, somatic mutation burden, mTORC1 signaling, cytokine profiles, and bone marrow changes. Participants must have a confirmed RUNX1-FPD diagnosis and a platelet count of at least 50,000/µL. Please share with patients who may be eligible. U.S.-based participants may also qualify for travel and lodging assistance. Learn more: runx1researchprogram.org/xSi…
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Danielle Hammond, MD retweeted
Join us at @UTMDAnderson Booth #110 during #SOHO2026 for a discussion on #VEXAS Syndrome with @danielleHammo20. Learn about this emerging hematologic and inflammatory disorder & connect with experts. 📅 View the full schedule: mdanderson.org/research/depa… @SocietyofHemOnc #HemeOnc
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Danielle Hammond, MD retweeted
Happy to see this out in @jhumimmunity. DADA2 has moved a long way from its first description as an early-onset stroke and vasculitis syndrome. In this review we take stock of where the field stands.
In a new review on DADA2, @IsabelleMeyts et al. cover the full spectrum of disease (vasculitis, bone marrow failure, immunodeficiency), TNF inhibitors, stem cell transplant, & #genetherapy on the horizon, the concept that a single variant can cause disease hubs.la/Q04rF_C20
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Danielle Hammond, MD retweeted
Officially published @jclinicalinvest - Evolution of clonal hematopoiesis during cancer treatment and its impact on outcomes @MoffittNews 🚨 It's not just whether clonal hematopoiesis (CH) is present - it's how it evolves that matters.🚨 jci.org/articles/view/204429
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Danielle Hammond, MD retweeted
Just out!! In @NEJM - Our randomized trial in myeloma (ENDURANCE trial) shows limited duration of lenalidomide maintenance is just as good as indefinite therapy, with less side effects!!! @eaonc @theNCI Implications are HUGE. This is a drug we spends billions on each year: -Less side effects -Less second cancers -Similar overall survival -Less cost @myelomaMD @Myeloma_Doc @SagarLonialMD National NCI funded trial led by @eaonc and joined by @ALLIANCE_org & @SWOG nejm.org/doi/full/10.1056/NE…
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Danielle Hammond, MD retweeted
👉👉👉Delighted to share our brand new paper 📝 just out in @BloodPortfolio ➡️major paper for our #BPDCN field ✅TAG/AZA/VEN clinical trial results for patients with #BPDCN | led by @lane_andy Dr Anthony Stein & @doctorpemm | #CD123 #BPDCN | #endcancer ashpublications.org/blood/ar…
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Danielle Hammond, MD retweeted
An important read on life and enjoying every day.
WARNING: Longer post (but worth reading or bookmarking for later). Your life has seasons. Each one is unique. Characterized by its own distinct desires, struggles, opportunities, and identity. But one reflection I've had recently is just how easy it is to completely disassociate with the present season. To give all your time and energy toward a longing for some nostalgic memory of a prior season or an anticipation for some beautiful state of a future season. You look back at the past and all you see is sunshine. Because it all worked out. You forget (or glaze over) the struggle you endured. You're here today. You made it. You're alive. You're doing fine. You look forward at the future and dream on what could be. You'll have so much more. More freedom. More purpose. More health. More deep connection. More everything. The past is beautiful and the future feels limitless. So, logically, you slowly start to treat everything about the present as the bridge. A dash connecting your past and your future. A gap to be crossed as quickly as possible. Everything you do today is in anticipation of some eventual end state. I'm doing this now, so that I can have that later. Unfortunately, the danger of that dissociation with the present is significant. You may spend your entire life living for a future that has a decidedly mirage-like property. You inch closer, but when it's right in front of you, it disappears and reappears on the horizon. You may spend your entire life skipping through the present, deferring your presence, your joy, and your very humanity to a future that never comes. In a classic French fable, a young boy is gifted with a magic ball of golden thread. He's told that if he simply pulls on the thread, time will leap forward. The catch, of course, is that once it's pulled, it can never be put back. The young boy takes advantage of the newfound powers. Each time he's faced with a boring day at school, a frustrating set of chores, or a scolding from his parents, he pulls the thread, skipping through to the good parts. As an adult, he continues, leaping through mundane struggles in his marriage, the friction of having a newborn, and the boredom at work. He finds himself pulling on the thread more and more, avoiding even the most minor inconveniences of his life. But when he wakes up one day and sees an old man looking back at him in the mirror, he's filled with regret. He realizes in that moment that as he chose to skip through the boredom, struggles, and friction, so too did he miss the real texture of being alive. How often do we all do the same? How easily do we default into this disassociation? Disconnecting from the present in anticipation of some future. A mentor recently asked me this: "Where are you going and why are you in such a rush?" It hit me hard. And to be honest, I haven't stopped replaying those words since he said them. Why are you in such a rush? The world wants you to rush into everything. Rushed decisions. Rushed conversations. Rushed relationships. Rushed timelines. In doing so, you slowly relinquish your agency. You give up your claim on your own life. Surrender authorship to a pen that was never even yours. In a world that wants you to rush, the ultimate act of rebellion is presence. Be in the season you're in. Don't romanticize the past, don't fantasize the future. Be here. Be now. Be in this. All of its texture, depth, and struggle. All of its joy, tension, and pain. Sit with the uncertainty. Become friends with it. Fall in love with it. Because every single thing you do today is something your younger self dreamed of and something your older self will wish they could go back and do. The good old days are happening, right now. And the next time you find yourself skipping through the present, remember these words: Where are you going and why are you in such a rush?
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Danielle Hammond, MD retweeted
🚨 A new study of 1.9 MILLION women with recurrent urinary tract infections found something remarkable. Women prescribed vaginal estrogen had lower rates of: ✅ Sepsis
✅ Hospitalization
✅ Death Let's talk about what this means. 🧵 sciencedirect.com/science/ar…
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Illuminating translational work re: leukemic pneumopathy and how this might be intercepted. 🔥🫁
Excited to share our study on immune interactions in extramedullary (lung) acute myeloid leukemia (AML) out today at @NatImmunol !! Acute respiratory failure frequently occurs in AML due to leukemia infiltration of the lungs. The question is why and what can we do to suppress it. @VarvaraParask in the lab started this work by mapping AML:stromal and AML:immune cell interactions using scRNA-Seq and Visium/Xenium @10xGenomics spatial tools. nature.com/articles/s41590-0…
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Danielle Hammond, MD retweeted
Knowledge is always progressing. Don’t let your ego fool you. You are always knowledge’s inferior.
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Clonal hematopoiesis meets immune regulation. Beautiful work 👌
Our autoimmunity paper is now OA in final form. We found a fascinating landscape of somatic evolution underpinning thyroid autoimmunity, where tens of B cell clones convergently lose immune checkpoints and some acquire 4-6 drivers over years of evolution. nature.com/articles/s41586-0…
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