Є̀ⲁmoռռ ᗰcClⲉⲁռ

I recently presented at the Vibrant Wellness Longevity Summit in Austin, Texas on strategies to extend lifespan, including vitamin D, omega-3, sulforaphane, and HIIT. You can find the full video here. youtube.com/watch?v=JelnAdNF…

Supplementation with cocoa flavanols slowed age-related inflammatory markers by 8.4%. Elevated inflammatory markers such as C-reactive protein (CRP) are strongly tied to cardiovascular disease. Cocoa supplementation has been shown to lower cardiovascular mortality by 27% over 3.6 years. There are also signals of a benefit for blood pressure, atrial fibrillation, and even eye health. This new study of nearly 600 older adults, followed for 2 years, found that daily supplementation with 500 mg of cocoa flavanols lowered high-sensitivity CRP, a key marker of chronic, age-related inflammation ('inflammaging'), by 8.4% per year compared to placebo. The benefits were most pronounced in people with higher inflammation at baseline, in women, and in those with diabetes. Other inflammatory markers (like IL-6 and TNF-α) didn’t change, pointing to a specific effect on CRP. Cocoa flavanols aren’t a magic bullet, but they may help dial down the silent inflammation that builds with age, offering one possible explanation for their cardiovascular benefits.

More exciting results from a pilot study on creatine supplementation for Alzheimer's disease. Participants who took 20 grams per day experienced a ~2 kg increase in handgrip strength and an increase in thigh muscle cross-sectional area after 8 weeks. That's without training. These findings complement those of a prior publication showing higher brain creatine levels and improved cognition in the same participants. Definitely an area of research to keep an eye on!